The pain of social disconnection: examining the shared neural underpinnings of physical and social pain (Q38007044)

26 August 2017

title

The pain of social disconnection: examining the shared neural underpinnings of physical and social pain (English)

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26 August 2017

1

Naomi I Eisenberger

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26 August 2017

language of work or name

English

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publication date

3 May 2012

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Nature Reviews Neuroscience

26 August 2017

published in

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26 August 2017

volume

13

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26 August 2017

issue

6

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26 August 2017

page(s)

421-434

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Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells

26 August 2017

cites work

1 reference

Allelic inactivation regulates olfactory receptor gene expression

21 January 2018

1 reference

Monoallelic expression and asynchronous replication of p120 catenin in mouse and human cells

21 January 2018

1 reference

Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells.

21 January 2018

1 reference

Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues

21 January 2018

1 reference

Variable patterns of axonal projections of sensory neurons in the mouse vomeronasal system

21 January 2018

1 reference

Widespread monoallelic expression on human autosomes

21 January 2018

1 reference

Autosomal monoallelic expression in the mouse

21 January 2018

1 reference

Allele-specific replication timing of imprinted gene regions

21 January 2018

1 reference

Asynchronous replication of imprinted genes is established in the gametes and maintained during development

21 January 2018

1 reference

An epigenetic signature for monoallelic olfactory receptor expression

21 January 2018

1 reference

Mice cloned from olfactory sensory neurons

21 January 2018

1 reference

Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons

21 January 2018

1 reference

Interchromosomal interactions and olfactory receptor choice

21 January 2018

1 reference

Genomic analysis of the olfactory receptor region of the mouse and human T-cell receptor alpha/delta loci

21 January 2018

1 reference

Negative Feedback Regulation Ensures the One Receptor-One Olfactory Neuron Rule in Mouse

21 January 2018

1 reference

Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis.

21 January 2018

1 reference

Identification of probabilistic transcriptional switches in the Ly49 gene cluster: a eukaryotic mechanism for selective gene activation

21 January 2018

1 reference

Mice with a "monoclonal nose": perturbations in an olfactory map impair odor discrimination

21 January 2018

1 reference

A feedback mechanism regulates monoallelic odorant receptor expression

21 January 2018

1 reference

Prominent roles for odorant receptor coding sequences in allelic exclusion

21 January 2018

1 reference

Gene switching and the stability of odorant receptor gene choice

21 January 2018

1 reference

Olfactory axons: a remarkable convergence

21 January 2018

1 reference

Early expression of odorant receptors distorts the olfactory circuitry

21 January 2018

1 reference

21 January 2018

1 reference

The evolution of gene duplications: classifying and distinguishing between models

21 January 2018

1 reference

Allelic divergence precedes and promotes gene duplication.

21 January 2018

1 reference

Genomic imprinting: parental influence on the genome

21 January 2018

1 reference

Genome-wide allele-specific analysis: insights into regulatory variation

21 January 2018

1 reference

Extensive sequence-influenced DNA methylation polymorphism in the human genome

21 January 2018

1 reference

Allelic skewing of DNA methylation is widespread across the genome

21 January 2018

1 reference

Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression

21 January 2018

1 reference

Biallelic germline transcription at the kappa immunoglobulin locus

21 January 2018

1 reference

Biallelic, ubiquitous transcription from the distal germline Ig{kappa} locus promoter during B cell development

21 January 2018

1 reference

A reappraisal of evidence for probabilistic models of allelic exclusion

21 January 2018

1 reference

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

21 January 2018

1 reference

Maintenance of MHC polymorphism

21 January 2018

1 reference

An abundance of X-linked genes expressed in spermatogonia

21 January 2018

1 reference

Asynchronous replication and allelic exclusion in the immune system

21 January 2018

1 reference

Monoallelic expression of the interleukin-2 locus

21 January 2018

1 reference

Allele-specific expression patterns of interleukin-2 and Pax-5 revealed by a sensitive single-cell RT-PCR analysis

31 March 2020

1 reference

Regulation of IL-4 expression by activation of individual alleles

31 March 2020

1 reference

Coordination of the random asynchronous replication of autosomal loci

31 March 2020

1 reference

Local and cis effects of the H element on expression of odorant receptor genes in mouse

31 March 2020

1 reference

Olfactory neurons are interdependent in maintaining axonal projections

31 March 2020

1 reference

YAC transgene-mediated olfactory receptor gene choice

31 March 2020

1 reference

Tissue and zonal-specific expression of an olfactory receptor transgene

31 March 2020

1 reference

Mutually exclusive expression of odorant receptor transgenes

31 March 2020

1 reference

Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation

31 March 2020

1 reference

The biology of social attachments: opiates alleviate separation distress

31 March 2020

1 reference

12 December 2020

Combinations of biomarkers predictive of later life mortality

1 reference

12 December 2020

The effect of cingulate lesions on social behaviour and emotion

1 reference

12 December 2020

Black sheep get the blues: a psychobiological model of social rejection and depression

1 reference

12 December 2020

Enhanced neural responses to rule violation in children with autism: a comparison to social exclusion

1 reference

12 December 2020

Deficit in attachment behavior in mice lacking the mu-opioid receptor gene

1 reference

12 December 2020

Social support and recovery from surgery

1 reference

12 December 2020

Social, blood/injury, and agoraphobic fears in patients with physically unexplained chronic pain: are they clinically significant?

1 reference

12 December 2020

Human fronto-mesolimbic networks guide decisions about charitable donation

1 reference

12 December 2020

Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis

1 reference

12 December 2020

The cortical representation of pain

1 reference

12 December 2020

Empathy for the social suffering of friends and strangers recruits distinct patterns of brain activation

1 reference

12 December 2020

The affective component of pain in rodents: direct evidence for a contribution of the anterior cingulate cortex

1 reference

12 December 2020

Acetaminophen reduces social pain: behavioral and neural evidence

1 reference

12 December 2020

Exploring the opioid system by gene knockout

1 reference

12 December 2020

Social ties and health: the benefits of social integration

1 reference

12 December 2020

The phenomenology of error processing: the dorsal ACC response to stop-signal errors tracks reports of negative affect.

1 reference

12 December 2020

Embodied grief: bereaved parents' narratives of their suffering body

1 reference

12 December 2020

Does Rejection Hurt? An fMRI Study of Social Exclusion

1 reference

12 December 2020

Functional magnetic resonance imaging responses relate to differences in real-world social experience

1 reference

12 December 2020

Study of psychological content in the communications of suicidal individuals

1 reference

12 December 2020

Psychological pain: a review of evidence

1 reference

12 December 2020

Craving love? Enduring grief activates brain's reward center

1 reference

12 December 2020

Anterior cingulate cortex responds differentially to expectancy violation and social rejection

1 reference

12 December 2020

Measuring symptoms of grief and bereavement

1 reference

12 December 2020

Opiate modulation of separation-induced distress in non-human primates

1 reference

12 December 2020

Conflict monitoring and anterior cingulate cortex: an update

1 reference

12 December 2020

State-dependent opioid control of pain

1 reference

12 December 2020

An experimental study of shared sensitivity to physical pain and social rejection

1 reference

12 December 2020

Dissociable brain mechanisms for processing social exclusion and rule violation

1 reference

12 December 2020

Why does social exclusion hurt? The relationship between social and physical pain

1 reference

12 December 2020

Opioid receptor function in social attachment in young domestic fowl

1 reference

12 December 2020

Pain affect encoded in human anterior cingulate but not somatosensory cortex.

1 reference

12 December 2020

Contributions of anterior cingulate cortex to behaviour

1 reference

12 December 2020

Understanding genetic risk for aggression: clues from the brain's response to social exclusion

1 reference

12 December 2020

Neural mechanisms of autonomic, affective, and cognitive integration

1 reference

12 December 2020

An FMRI investigation of attributing negative social treatment to racial discrimination.

1 reference

12 December 2020

Human brain mechanisms of pain perception and regulation in health and disease.

1 reference

12 December 2020

Emotional processing in anterior cingulate and medial prefrontal cortex

1 reference

12 December 2020

Brain mediators of cardiovascular responses to social threat, part II: Prefrontal-subcortical pathways and relationship with anxiety

1 reference

12 December 2020

How do we perceive the pain of others? A window into the neural processes involved in empathy

1 reference

12 December 2020

I feel your pain: emotional closeness modulates neural responses to empathically experienced rejection.

1 reference

12 December 2020

Social-evaluative threat and proinflammatory cytokine regulation: an experimental laboratory investigation

1 reference

12 December 2020

Tension-type headache as the unique pain experience of a patient with congenital insensitivity to pain.

1 reference

12 December 2020

Reversible pain and tactile deficits associated with a cerebral tumor compressing the posterior insula and parietal operculum

1 reference

12 December 2020

Cognitive and emotional influences in anterior cingulate cortex

1 reference

12 December 2020

Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence

1 reference

12 December 2020

The function of the median cerebral cortex in maternal behavior of rats.

1 reference

12 December 2020

Region-specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis

1 reference

12 December 2020

Organization of Endogenous Opiate and Nonopiate Pain Control Systems

1 reference

12 December 2020

Development of ACC-amygdala activations in processing unattended fear.

1 reference

12 December 2020

The unpleasantness of tonic pain is encoded by the insular cortex

1 reference

12 December 2020

Maternal behavior of mice with cingulate cortical, amygdala, or septal lesions

1 reference

12 December 2020

Functional imaging of an illusion of pain

1 reference

12 December 2020

An fMRI investigation of responses to peer rejection in adolescents with autism spectrum disorders

1 reference

12 December 2020

When your gain is my pain and your pain is my gain: neural correlates of envy and schadenfreude

1 reference

12 December 2020

Functional Neuroanatomy of Grief: An fMRI Study

1 reference

12 December 2020

Congenital insensitivity to pain: an update

1 reference

12 December 2020

The need to belong: desire for interpersonal attachments as a fundamental human motivation

1 reference

12 December 2020

Pain "relief" by frontal cingulumotomy

1 reference

12 December 2020

Effects of morphine and naloxone on separation distress and approach attachment: Evidence for opiate mediation of social affect

1 reference

12 December 2020

In-group and out-group membership mediates anterior cingulate activation to social exclusion

1 reference

12 December 2020

Anterior cingulectomy in man

1 reference

12 December 2020

Loneliness matters: a theoretical and empirical review of consequences and mechanisms

1 reference

12 December 2020

Decreased ventral anterior cingulate cortex activity is associated with reduced social pain during emotional support.

1 reference

12 December 2020

Early attachment-figure separation and increased risk for later depression: potential mediation by proinflammatory processes.

1 reference

12 December 2020

Social regulation of gene expression in human leukocytes

1 reference

12 December 2020

High opiate receptor binding potential in the human lateral pain system

1 reference

12 December 2020

The Triune Brain in Evolution. Role in Paleocerebral Functions. Paul D. MacLean. Plenum, New York, 1990. xxiv, 672 pp., illus. $75.

1 reference

12 December 2020

Pain sensitivity alterations as a function of lesion location in the parasylvian cortex

1 reference

12 December 2020

The pain of being sick: implications of immune-to-brain communication for understanding pain

1 reference

12 December 2020

Does low self-esteem enhance social pain? The relationship between trait self-esteem and anterior cingulate cortex activation induced by ostracism

1 reference

12 December 2020

Neural pathways link social support to attenuated neuroendocrine stress responses

1 reference

12 December 2020

Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy

1 reference

12 December 2020

Neural dynamics of rejection sensitivity

1 reference

12 December 2020

Brain mediators of cardiovascular responses to social threat: part I: Reciprocal dorsal and ventral sub-regions of the medial prefrontal cortex and heart-rate reactivity

1 reference

12 December 2020

Viewing pictures of a romantic partner reduces experimental pain: involvement of neural reward systems

1 reference

12 December 2020

Effects of cingulate cortical lesions on avoidance learning and training-induced unit activity in rabbits

1 reference

12 December 2020

Asymbolia for pain: A sensory-limbic disconnection syndrome

1 reference

12 December 2020

Why rejection hurts: a common neural alarm system for physical and social pain

1 reference

12 December 2020

Opiate antagonists stimulate affiliative behaviour in monkeys

1 reference

12 December 2020

A picture's worth: partner photographs reduce experimentally induced pain

1 reference

12 December 2020

Pain affect without pain sensation in a patient with a postcentral lesion.

1 reference

12 December 2020

Impact of shock on pain reactivity: II. Evidence for enhanced pain.

1 reference

12 December 2020

Cytokine-associated emotional and cognitive disturbances in humans

1 reference

12 December 2020

Role of midline frontolimbic cortex in production of the isolation call of squirrel monkeys

1 reference

12 December 2020

Treatment of psychiatric illness by stereotactic cingulotomy

1 reference

12 December 2020

The integration of negative affect, pain and cognitive control in the cingulate cortex

1 reference

12 December 2020

Attachment figures activate a safety signal-related neural region and reduce pain experience

1 reference

12 December 2020

In vivo distribution of opioid receptors in man in relation to the cortical projections of the medial and lateral pain systems measured with positron emission tomography

1 reference

12 December 2020

Personality changes after operations on the cingulate gyrus in man

1 reference

12 December 2020

Failure hurts: the effects of stress due to difficult tasks and failure feedback on pain report

1 reference

12 December 2020

Attachment theory: a model for health care utilization and somatization

1 reference

12 December 2020

An fMRI investigation of empathy for 'social pain' and subsequent prosocial behavior.

1 reference

12 December 2020

How do you feel? Interoception: the sense of the physiological condition of the body

1 reference

12 December 2020

Species-typical behavior of hamsters deprived from birth of the neocortex

1 reference

12 December 2020

Reward, addiction, and emotion regulation systems associated with rejection in love

1 reference

12 December 2020

Social exclusion and punishment of excluders: neural correlates and developmental trajectories.

1 reference

12 December 2020

A psychophysical analysis of morphine analgesia

1 reference

12 December 2020

Developmental influences on the neural bases of responses to social rejection: implications of social neuroscience for education.

1 reference

12 December 2020

When hurt will not heal: exploring the capacity to relive social and physical pain.

1 reference

12 December 2020

Pain demands attention: a cognitive-affective model of the interruptive function of pain

1 reference

12 December 2020

The neural sociometer: brain mechanisms underlying state self-esteem

1 reference

12 December 2020

Meta-analytic evidence for common and distinct neural networks associated with directly experienced pain and empathy for pain

1 reference

12 December 2020

Mapping the road from childhood trauma to adult somatization: the role of attachment

1 reference

12 December 2020

Pain during depression and relationship to rejection sensitivity

1 reference

12 December 2020

Social exclusion and pain sensitivity: why exclusion sometimes hurts and sometimes numbs

1 reference

12 December 2020

Psychological and neural mechanisms of the affective dimension of pain

1 reference

12 December 2020

Variation in the mu-opioid receptor gene (OPRM1) is associated with dispositional and neural sensitivity to social rejection

1 reference

12 December 2020

Morphine reduces social cohesion in rats.

1 reference

12 December 2020

Fear and anxiety: divergent effects on human pain thresholds.

1 reference

12 December 2020

Neural correlates of social exclusion during adolescence: understanding the distress of peer rejection

1 reference

12 December 2020

Neural activation underlying acute grief in women after the loss of an unborn child

1 reference

12 December 2020

Pain perception: is there a role for primary somatosensory cortex?

1 reference

12 December 2020

Cancer pain and psychosocial factors: a critical review of the literature

1 reference

12 December 2020

Time spent with friends in adolescence relates to less neural sensitivity to later peer rejection

1 reference

12 December 2020

Reciprocal regulation of the neural and innate immune systems

1 reference

12 December 2020

Alone but feeling no pain: Effects of social exclusion on physical pain tolerance and pain threshold, affective forecasting, and interpersonal empathy

1 reference

12 December 2020

Neurophysiology and functional neuroanatomy of pain perception

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12 December 2020

Cortical representation of the sensory dimension of pain.

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12 December 2020

Neural sensitivity to social rejection is associated with inflammatory responses to social stress

1 reference

12 December 2020

Social rejection shares somatosensory representations with physical pain

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12 December 2020

The neural bases of social pain: evidence for shared representations with physical pain

1 reference

12 December 2020

Differential brain responses to social exclusion by one's own versus opposite-gender peers

1 reference

12 December 2020

Inflammation and social experience: an inflammatory challenge induces feelings of social disconnection in addition to depressed mood

1 reference

12 December 2020

Suicidality in chronic pain: a review of the prevalence, risk factors and psychological links

1 reference

12 December 2020

Attention to pain localization and unpleasantness discriminates the functions of the medial and lateral pain systems.

1 reference

12 December 2020

Neural correlates of giving support to a loved one.

1 reference

12 December 2020

Dissociation, childhood interpersonal trauma, and family functioning in patients with somatization disorder.

1 reference

12 December 2020

Somatosensation in social perception

1 reference

12 December 2020

Cutting edge: Sympathetic nervous system increases proinflammatory cytokines and exacerbates influenza A virus pathogenesis

1 reference

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The face of rejection: rejection sensitivity moderates dorsal anterior cingulate activity to disapproving facial expressions

1 reference

12 December 2020

An fMRI study of cytokine-induced depressed mood and social pain: the role of sex differences

1 reference

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Does failure hurt? The effects of failure feedback on pain report, pain tolerance and pain avoidance

1 reference

12 December 2020

Ideational components of anxiety neurosis.

1 reference

12 December 2020

Do neural responses to rejection depend on attachment style? An fMRI study

1 reference

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Identifiers

DOI

10.1038/NRG3239

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Dimensions Publication ID

26 August 2017

1031942051

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