The emerging challenge in diabetes: the "metabolic memory". (Q38011508)

27 August 2017

The emerging challenge in diabetes: the "metabolic memory". (English)

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27 August 2017

1

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27 August 2017

16 May 2012

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27 August 2017

Vascular Pharmacology

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27 August 2017

57

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27 August 2017

133-138

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27 August 2017

5-6

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Glycated and oxidized protein degradation products are indicators of fasting and postprandial hyperglycemia in diabetes

27 August 2017

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Oxidative stress and gene regulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Alpha-oxoaldehyde metabolism and diabetic complications

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Biochemistry and molecular cell biology of diabetic complications

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

New Insights on Oxidative Stress and Diabetic Complications May Lead to a “Causal” Antioxidant Therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Postprandial hyperglycemia and diabetes complications: is it time to treat?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

'Glycaemic variability': a new therapeutic challenge in diabetes and the critical care setting

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Postprandial glucose regulation and diabetic complications

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Effect of postprandial hypertriglyceridemia and hyperglycemia on circulating adhesion molecules and oxidative stress generation and the possible role of simvastatin treatment

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Effect of atorvastatin and irbesartan, alone and in combination, on postprandial endothelial dysfunction, oxidative stress, and inflammation in type 2 diabetic patients

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Simultaneous Control of Hyperglycemia and Oxidative Stress Normalizes Endothelial Function in Type 1 Diabetes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Telmisartan Shows an Equivalent Effect of Vitamin C in Further Improving Endothelial Dysfunction After Glycemia Normalization in Type 1 Diabetes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Long-term glycemic control influences the long-lasting effect of hyperglycemia on endothelial function in type 1 diabetes.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Effect of acute hyperglycaemia, long-term glycaemic control and insulin on endothelial dysfunction and inflammation in Type 1 diabetic patients with different characteristics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Endothelium-dependent and independent vasodilation studies at normoglycaemia in type I diabetes mellitus with and without microalbuminuria.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Endothelial dysfunction: a comprehensive appraisal

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Oxidants, oxidative stress and the biology of ageing

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Effect of a multifactorial intervention on mortality in type 2 diabetes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complicat

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

The human mitochondrial proteome: oxidative stress, protein modifications and oxidative phosphorylation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Vascular effects of acute hyperglycemia in humans are reversed by L-arginine. Evidence for reduced availability of nitric oxide during hyperglycemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Long-term follow-up after tight control of blood pressure in type 2 diabetes.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Endothelium-dependent vasodilatation, plasma markers of endothelial function, and adrenergic vasoconstrictor responses in type 1 diabetes under near-normoglycemic conditions

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Effect of methylglyoxal on human leukaemia 60 cell growth: Modification of DNA, G1 growth arrest and induction of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

High serum levels of advanced glycation end products predict increased coronary heart disease mortality in nondiabetic women but not in nondiabetic men: a population-based 18-year follow-up study

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kappaB) in the retina.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Reversal of hyperglycemia and diabetic nephropathy: effect of reinstitution of good metabolic control on oxidative stress in the kidney of diabetic rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Importance of measuring products of non-enzymatic glycation of proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Acute hyperglycemia induces a global downregulation of gene expression in adipose tissue and skeletal muscle of healthy subjects.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Regulation of gene expression by glucose

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: biochemical mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT S

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Pretreatment with intravenous ascorbic acid preserves endothelial function during acute hyperglycaemia (R1).

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Identification of N2-(1-carboxyethyl)guanine (CEG) as a guanine advanced glycosylation end product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Progression of carotid artery intima-media thickness during 12 years in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Evidence that pioglitazone, metformin and pentoxifylline are inhibitors of glycation.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

The role of AMP-activated protein kinase in mitochondrial biogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Defining the relationship between plasma glucose and HbA(1c): analysis of glucose profiles and HbA(1c) in the Diabetes Control and Complications Trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Overexpression of fibronectin induced by diabetes or high glucose: phenomenon with a memory

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor kappaB in PBMCs

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Partial depletion of mitochondrial DNA from human skin fibroblasts induces a gene expression profile reminiscent of photoaged skin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Targeting antioxidants to mitochondria: a new therapeutic direction

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Impaired vascular function during short-term poor glycaemic control in Type 1 diabetic patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Enzymatic deglycation of proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

Mitochondrial ROS-induced ROS release: an update and review

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2012.05.005

10.1016/J.VPH.2012.05.005

7 January 2021

Identifiers

DOI

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27 August 2017

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PubMed ID

22609133