Methodologies used to identify and characterize interactions among antiepileptic drugs (Q38018676)

27 August 2017

title

Methodologies used to identify and characterize interactions among antiepileptic drugs (English)

1 reference

Cecilie Johannessen Landmark

27 August 2017

author

series ordinal

1

object named as

Cecilie Johannessen Landmark

1 reference

27 August 2017

Philip N Patsalos

2

1 reference

27 August 2017

language of work or name

English

0 references

publication date

1 May 2012

1 reference

Expert Review of Clinical Pharmacology

27 August 2017

published in

1 reference

27 August 2017

volume

5

1 reference

27 August 2017

issue

3

1 reference

27 August 2017

page(s)

281-292

1 reference

Clinical use of antiepileptic drugs at a referral centre for epilepsy.

27 August 2017

cites work

1 reference

Prescription patterns of antiepileptic drugs in patients with epilepsy in a nation-wide population.

21 January 2018

1 reference

Trends in utilization of antiepileptic drugs in Denmark

21 January 2018

1 reference

Antiepileptic drug use in community-dwelling and institutionalized elderly: a nationwide study of over 1,300,000 older people

21 January 2018

1 reference

Combining antiepileptic drugs--rational polytherapy?

21 January 2018

1 reference

Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed

21 January 2018

1 reference

Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments?

21 January 2018

1 reference

Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam

21 January 2018

1 reference

Levetiracetam and felbamate interact both pharmacodynamically and pharmacokinetically: an isobolographic analysis in the mouse maximal electroshock model

21 January 2018

1 reference

Pharmacodynamic and pharmacokinetic characterization of interactions between levetiracetam and numerous antiepileptic drugs in the mouse maximal electroshock seizure model: an isobolographic analysis

21 January 2018

1 reference

Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy

21 January 2018

1 reference

Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model.

21 January 2018

1 reference

Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis.

21 January 2018

1 reference

Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model

21 January 2018

1 reference

The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction.

21 January 2018

1 reference

Disabling tremor after lamotrigine with sodium valproate

21 January 2018

1 reference

Clinically relevant drug interactions with antiepileptic drugs

21 January 2018

1 reference

Carbamazepine toxicity with lamotrigine: pharmacokinetic or pharmacodynamic interaction?

21 January 2018

1 reference

A pooled analysis of lacosamide clinical trial data grouped by mechanism of action of concomitant antiepileptic drugs

21 January 2018

1 reference

Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs

21 January 2018

1 reference

Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs

21 January 2018

1 reference

Drug interactions involving the new second- and third-generation antiepileptic drugs

21 January 2018

1 reference

UDP-glucuronosyltransferases and clinical drug-drug interactions

21 January 2018

1 reference

Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring

21 January 2018

1 reference

Impact of CYP2C19 polymorphisms on the efficacy of clobazam therapy

21 January 2018

1 reference

Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs

21 January 2018

1 reference

The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy

21 January 2018

1 reference

Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects

21 January 2018

1 reference

Exploring the possible interaction between anti-epilepsy drugs and multidrug efflux pumps; in vitro observations

21 January 2018

1 reference

Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs

21 January 2018

1 reference

ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy

21 January 2018

1 reference

Several major antiepileptic drugs are substrates for human P-glycoprotein

21 January 2018

1 reference

Prediction of drug-drug interactions of zonisamide metabolism in humans from in vitro data

21 January 2018

1 reference

Topiramate and phenytoin pharmacokinetics during repetitive monotherapy and combination therapy to epileptic patients

21 January 2018

1 reference

Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction.

21 January 2018

1 reference

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans

21 January 2018

1 reference

In vitro and in vivo drug interactions involving human CYP3A.

21 January 2018

1 reference

Prediction of in vivo drug-drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

21 January 2018

1 reference

Prediction of in vivo drug-drug interactions from in vitro data : factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6 and CYP3A4.

21 January 2018

1 reference

Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction

21 January 2018

1 reference

Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytes

21 January 2018

1 reference

Comparative use of isolated hepatocytes and hepatic microsomes for cytochrome P450 inhibition studies: transporter-enzyme interplay.

21 January 2018

1 reference

Comparison of serum, cerebrospinal fluid and brain extracellular fluid pharmacokinetics of lamotrigine

21 January 2018

1 reference

A useful tool for drug interaction evaluation: the University of Washington Metabolism and Transport Drug Interaction Database

21 January 2018

1 reference

Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects

21 January 2018

1 reference

Pharmacokinetic interaction study between eslicarbazepine acetate and lamotrigine in healthy subjects

21 January 2018

1 reference

Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy

21 January 2018

1 reference

Lamotrigine plasma levels reduced by oral contraceptives

21 January 2018

1 reference

Oral contraceptives reduce lamotrigine plasma levels

21 January 2018

1 reference

Ethinyl estradiol, not progestogens, reduces lamotrigine serum concentrations.

21 January 2018

1 reference

Effects of antiepileptic comedication on levetiracetam pharmacokinetics: a pooled analysis of data from randomized adjunctive therapy trials

21 January 2018

1 reference

Rufinamide: clinical pharmacokinetics and concentration-response relationships in patients with epilepsy

21 January 2018

1 reference

Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: a randomized placebo-controlled trial

21 January 2018

1 reference

Population pharmacokinetics of levetiracetam and dosing recommendation in children with epilepsy.

21 January 2018

1 reference

Adjunctive lacosamide for partial-onset seizures: Efficacy and safety results from a randomized controlled trial

21 January 2018

1 reference

Therapeutic drug monitoring of the newer antiepileptic drugs

21 January 2018

1 reference

Trends and changes in the clinical use of lamotrigine.

21 January 2018

1 reference

Serum concentrations of topiramate in patients with epilepsy: influence of dose, age, and comedication

21 January 2018

1 reference

Serum concentrations of Levetiracetam in epileptic patients: the influence of dose and co-medication

21 January 2018

1 reference

Serum concentrations of pregabalin in patients with epilepsy: the influence of dose, age, and comedication

21 January 2018

1 reference

Antiepileptic drugs in epilepsy and other disorders--a population-based study of prescriptions

21 January 2018

1 reference

Antiepileptic drug utilization in children from 1997-2005--a study from the Netherlands

21 January 2018

1 reference

Changing trends in antiepileptic drug prescribing in girls of child-bearing potential.

21 January 2018

1 reference

Comparison of antiepileptic drug prescribing in children in three European countries

21 January 2018

1 reference

Effect of antiepileptic drug comedication on lamotrigine clearance

21 January 2018

1 reference

The effect of age and comedication on lamotrigine clearance, tolerability, and efficacy

21 January 2018

1 reference

Pharmacokinetics and metabolism of 14C-brivaracetam, a novel SV2A ligand, in healthy subjects

21 January 2018

1 reference

Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X).

21 January 2018

1 reference

Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V).

21 January 2018

1 reference

In Situ Metabolism of Levetiracetam in Blood of Patients with Epilepsy

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ECP.12.10

1 reference

27 August 2017

1 reference