Novel methodologies in metabolic profiling with a focus on molecular diagnostic applications (Q38019000)

27 August 2017

Novel methodologies in metabolic profiling with a focus on molecular diagnostic applications (English)

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27 August 2017

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1

Tuulia Hyötyläinen

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27 August 2017

1 June 2012

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

27 August 2017

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27 August 2017

12

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27 August 2017

5

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27 August 2017

527-538

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Liquid chromatography-mass spectrometry based global metabolite profiling: a review.

27 August 2017

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Lactate in solid malignant tumors: potential basis of a metabolic classification in clinical oncology

21 January 2018

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Metabolomics: moving to the clinic

21 January 2018

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Rationale for biomarkers and surrogate end points in mechanism-driven oncology drug development

21 January 2018

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Urinary metabolite quantification employing 2D NMR spectroscopy.

21 January 2018

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Matrix-assisted laser desorption/ionisation mass spectrometry imaging of lipids in rat brain tissue with integrated unsupervised and supervised multivariant statistical analysis

21 January 2018

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Spatial distribution of glycerophospholipids in the ocular lens

21 January 2018

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Rapid, direct analysis of cholesterol by charge labeling in reactive desorption electrospray ionization

21 January 2018

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In vivo solid-phase microextraction in metabolomics: opportunities for the direct investigation of biological systems

21 January 2018

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Mass spectrometry-based metabolomics

21 January 2018

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Advances in mass spectrometry applied to pharmaceutical metabolomics.

21 January 2018

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Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses

21 January 2018

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Metabolomic study of insomnia and intervention effects of Suanzaoren decoction using ultra-performance liquid-chromatography/electrospray-ionization synapt high-definition mass spectrometry

21 January 2018

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Application of comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry method to identify potential biomarkers of perinatal asphyxia in a non-human primate model

21 January 2018

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Data analysis tool for comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry

21 January 2018

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Metabolome in progression to Alzheimer's disease

21 January 2018

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Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread

21 January 2018

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Imaging mass spectrometry: hype or hope?

21 January 2018

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MALDI imaging mass spectrometry: molecular snapshots of biochemical systems

21 January 2018

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Desorption electrospray ionization mass spectrometry: Imaging drugs and metabolites in tissues

21 January 2018

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Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models

21 January 2018

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Tissue imaging at atmospheric pressure using desorption electrospray ionization (DESI) mass spectrometry

21 January 2018

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Cellular imaging with secondary ion mass spectrometry

21 January 2018

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Protein and peptides in pictures: imaging with MALDI mass spectrometry

21 January 2018

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Metabolic phenotyping for monitoring surgical patients

21 January 2018

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NMR techniques in biomedical and pharmaceutical analysis

21 January 2018

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Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts

21 January 2018

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Towards automatic metabolomic profiling of high-resolution one-dimensional proton NMR spectra.

21 January 2018

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Metabolomic analysis using optimized NMR and statistical methods

21 January 2018

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Chip-NMR biosensor for detection and molecular analysis of cells

21 January 2018

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FiehnLib: Mass Spectral and Retention Index Libraries for Metabolomics Based on Quadrupole and Time-of-Flight Gas Chromatography/Mass Spectrometry

21 January 2018

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GMD@CSB.DB: the Golm Metabolome Database

21 January 2018

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Decision tree supported substructure prediction of metabolites from GC-MS profiles

21 January 2018

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Applying in-silico retention index and mass spectra matching for identification of unknown metabolites in accurate mass GC-TOF mass spectrometry

21 January 2018

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METLIN: a metabolite mass spectral database

21 January 2018

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MassBank: a public repository for sharing mass spectral data for life sciences

21 January 2018

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In silico fragmentation for computer assisted identification of metabolite mass spectra

21 January 2018

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Computational mass spectrometry for metabolomics: identification of metabolites and small molecules

21 January 2018

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Matching structures to mass spectra using fragmentation patterns: are the results as good as they look?

21 January 2018

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Data processing for mass spectrometry-based metabolomics

21 January 2018

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MZmine 2: modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

21 January 2018

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Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements

21 January 2018

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A comprehensive urinary metabolomic approach for identifying kidney cancerr

21 January 2018

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Metabolomic analysis and visualization engine for LC-MS data

21 January 2018

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21 January 2018

Data mining in genomics

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Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation

21 January 2018

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Pathway Activity Profiling (PAPi): from the metabolite profile to the metabolic pathway activity.

21 January 2018

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MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data

21 January 2018

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Global reconstruction of the human metabolic network based on genomic and bibliomic data

21 January 2018

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Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism

21 January 2018

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Use of constraint-based modeling for the prediction and validation of antimicrobial targets

21 January 2018

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Predicting metabolic biomarkers of human inborn errors of metabolism

21 January 2018

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Inborn errors of metabolism: the flux from Mendelian to complex diseases.

21 January 2018

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Amyloid-beta(1-42), total tau, and phosphorylated tau as cerebrospinal fluid biomarkers for the diagnosis of Alzheimer disease.

21 January 2018

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Biomarkers of Alzheimer disease in plasma

21 January 2018

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Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study.

21 January 2018

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Plasma Abeta in Alzheimer's disease--up or down?

21 January 2018

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Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease.

21 January 2018

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Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer

21 January 2018

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MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status

21 January 2018

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Molecular causes of the aberrant choline phospholipid metabolism in breast cancer

21 January 2018

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Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression

21 January 2018

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An HR-MAS MR metabolomics study on breast tissues obtained with core needle biopsy

21 January 2018

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Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: application to the detection of breast cancer

21 January 2018

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The role of liquid chromatography-tandem mass spectrometry in the clinical laboratory

21 January 2018

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HMDB: the Human Metabolome Database

21 January 2018

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Liquid Chromatography-Mass Spectrometry (LC-MS)-Based Lipidomics for Studies of Body Fluids and Tissues

21 January 2018

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MPEA—metabolite pathway enrichment analysis

21 January 2018

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Characterization of Isotopic Abundance Measurements in High Resolution FT-ICR and Orbitrap Mass Spectra for Improved Confidence of Metabolite Identification

21 January 2018

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Metabolomic NMR Fingerprinting to Identify and Predict Survival of Patients with Metastatic Colorectal Cancer

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERM.12.33

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27 August 2017

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PubMed ID

22702368