Generation of natural killer cells from hematopoietic stem cells in vitro for immunotherapy (Q38019320)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Generation of natural killer cells from hematopoietic stem cells in vitro for immunotherapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

2

1 reference

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5 February 2020

Aurore Saudemont

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1

Martha Luevano

1 reference

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5 February 2020

publication date

18 June 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Immunology

5 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

4

1 reference

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5 February 2020

page(s)

310-320

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cmi.2012.17

5 February 2020

exact match

0 references

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6 September 2017

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6 September 2017

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6 September 2017

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Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells

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6 September 2017

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Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity

6 September 2017

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IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

6 September 2017

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A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Human natural killer cell development

6 September 2017

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Cancer regression in patients after transfer of genetically engineered lymphocytes

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

6 September 2017

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Differentiation plasticity of hematopoietic cells

6 September 2017

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NK cells, MHC class I molecules and the missing self

6 September 2017

1 reference

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Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation

6 September 2017

1 reference

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Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

6 September 2017

1 reference

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The biology of human natural killer-cell subsets

6 September 2017

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High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

6 September 2017

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Association of a syndrome resembling Wegener's granulomatosis with low surface expression of HLA class-I molecules

6 September 2017

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Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

6 September 2017

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6 September 2017

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Generation of lytic natural killer 1.1+, Ly-49- cells from multipotential murine bone marrow progenitors in a stroma-free culture: definition of cytokine requirements and developmental intermediates

6 September 2017

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Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12.

6 September 2017

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Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes

6 September 2017

1 reference

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Expression of a functional c-kit receptor on a subset of natural killer cells

6 September 2017

1 reference

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„Natural” killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell

6 September 2017

1 reference

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Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells

6 September 2017

1 reference

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Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic acid allogeneic tumors. I. Distribution of reactivity and specificity

6 September 2017

1 reference

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IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a phase I clinical study.

6 September 2017

1 reference

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Good manufacturing practice-compliant cell sorting and large-scale expansion of single KIR-positive alloreactive human natural killer cells for multiple infusions to leukemia patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Characterization of functional surface structures on human natural killer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

The Notch ligands Jagged2, Delta1, and Delta4 induce differentiation and expansion of functional human NK cells from CD34+ cord blood hematopoietic progenitor cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Infusion of the allogeneic cell line NK-92 in patients with advanced renal cell cancer or melanoma: a phase I trial

14 September 2017

1 reference

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Human NK cell education by inhibitory receptors for MHC class I.

14 September 2017

1 reference

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Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Autologous natural killer cell therapy for human recurrent malignant glioma.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Suppression of natural killer cell activity with radioactive strontium: effector cells are marrow dependent

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2/L3/S2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Stable transduction of the interleukin-2 gene into human natural killer cell lines and their phenotypic and functional characterization in vitro and in vivo.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

In vitro maintenance of highly purified, transplantable hematopoietic stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Generation of human natural killer cells from peripheral blood CD34+ cells mobilized by granulocyte colony-stimulating factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Interleukin 15 induction of lymphokine-activated killer cell function against autologous tumor cells in melanoma patient lymphocytes by a CD18-dependent, perforin-related mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Human natural killer cell expansion is regulated by thrombospondin-mediated activation of transforming growth factor-beta 1 and independent accessory cell-derived contact and soluble factors.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Generation of allospecific natural killer cells by stimulation across a polymorphism of HLA-C.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Natural killer cell proliferation is dependent on human serum and markedly increased utilizing an enriched supplemented basal medium

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Natural killer (NK)-resistant human lung cancer cells are lysed by recombinant interleukin-2-activated NK cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Identification of a ligand for the c-kit proto-oncogene

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

„Natural”︁ killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Different NK cell developmental events require different levels of IL-15 trans-presentation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

CD56brightCD16+ NK cells: a functional intermediate stage of NK cell differentiation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Generation of natural killer cells from serum-free, expanded human umbilical cord blood CD34+ cells.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Effect of IL-21 on NK cells derived from different umbilical cord blood populations

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

Licensing of natural killer cells by host major histocompatibility complex class I molecules

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012863

A human CD34(+) subset resides in lymph nodes and differentiates into CD56bright natural killer cells

31 August 2018

1 reference

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IL-2 activated NK cell immunotherapy of three children after haploidentical stem cell transplantation

31 August 2018

1 reference

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Expansion of cytotoxic effectors with lytic activity against autologous blasts from acute myeloid leukaemia patients in complete haematological remission

31 August 2018

1 reference

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Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset

31 August 2018

1 reference

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The receptor tyrosine kinase c-kit provides a critical signal for survival, expansion, and maturation of mouse natural killer cells.

31 August 2018

1 reference

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Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay

31 August 2018

1 reference

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Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation.

31 August 2018

1 reference

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Flt3 ligand promotes the generation of a distinct CD34(+) human natural killer cell progenitor that responds to interleukin-15.

31 August 2018

1 reference

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Immunotherapy with interleukin-2 (IL2) and lymphokine-activated natural killer cells: improvement of clinical responses in metastatic renal cell carcinoma patients previously treated with IL2.

31 August 2018

1 reference

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Differentiation of natural killer (NK) cells from human primitive marrow progenitors in a stroma-based long-term culture system: identification of a CD34+7+ NK progenitor.

31 August 2018

1 reference

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Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCMI.2012.17

A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCMI.2012.17

Adoptive transfer of gene-modified primary NK cells can specifically inhibit tumor progression in vivo

21 January 2018

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12 December 2020

Ex-vivo expansion of NK cells: what is the priority--high yield or high purity?

1 reference

12 December 2020

Interleukin-15-induced maturation of human natural killer cells from early thymic precursors: selective expression of CD94/NKG2-A as the only HLA class I-specific inhibitory receptor

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12 December 2020

An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation

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12 December 2020

Cryopreservation of human lymphocytes for assessment of lymphocyte subsets and natural killer cytotoxicity

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12 December 2020

In vitro and in vivo evidence for the long-term multilineage (myeloid, B, NK, and T) reconstitution capacity of ex vivo expanded human CD34(+) cord blood cells

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12 December 2020

Human NK cell development in NOD/SCID mice receiving grafts of cord blood CD34+ cells

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12 December 2020

Posttransplant adoptive immunotherapy with activated natural killer cells in patients with metastatic breast cancer

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12 December 2020

Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor

1 reference

12 December 2020

Anti-myeloma activity of endogenous and adoptively transferred activated natural killer cells in experimental multiple myeloma model

1 reference

12 December 2020

Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity

1 reference

12 December 2020

Ex vivo expansion of natural killer cells: a question of function

1 reference

12 December 2020

Purified donor NK-lymphocyte infusion to consolidate engraftment after haploidentical stem cell transplantation

1 reference

12 December 2020

Human natural killer cells: a convenient purification procedure and the influence of cryopreservation on cytotoxic activity

1 reference

12 December 2020

Natural killer cell differentiation: insights from knockout and transgenic mouse models and in vitro systems

1 reference

12 December 2020

Autologous peripheral blood stem cell transplantation and adoptive immunotherapy with activated natural killer cells in the immediate posttransplant period

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12 December 2020

Lymphokine requirement for the generation of natural killer cells from CD34+ hematopoietic progenitor cells

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12 December 2020

Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2

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12 December 2020

Natural killer cells: definition of a cell type rather than a function

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12 December 2020

Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells

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12 December 2020

Efficacy of large doses of IL-2-activated human leukocyte antigen haploidentical peripheral blood stem cells on refractory metastatic renal cell carcinoma

1 reference

12 December 2020

Posttraumatic splenectomy does not influence human peripheral blood mononuclear cell subsets

1 reference

12 December 2020

Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components

1 reference

12 December 2020

Antitumor effect of large doses IL-2-activated HLA haploidentical peripheral blood stem cells on refractory metastatic solid tumor treatment

1 reference

12 December 2020

Prevention of graft versus host disease by inactivation of host antigen-presenting cells

1 reference

12 December 2020

Phenotypic and functional evaluation of natural killer cells in thymectomized children

1 reference

12 December 2020

Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood

1 reference

12 December 2020

Expansion of NK cells from cord blood with antileukemic activity using GMP-compliant substances without feeder cells

1 reference

12 December 2020

In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells

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12 December 2020

Identifiers

DOI

10.1038/CMI.2012.17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22705914%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference