Coordination between RAB GTPase and phosphoinositide regulation and functions (Q38020744)

27 August 2017

Coordination between RAB GTPase and phosphoinositide regulation and functions (English)

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27 August 2017

Steve Jean

1

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27 August 2017

Amy A Kiger

series ordinal

2

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27 August 2017

language of work or name

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22 June 2012

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Nature Reviews Molecular Cell Biology

27 August 2017

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27 August 2017

13

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27 August 2017

463-470

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27 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/nrm3379

27 August 2017

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cites work

Function and dysfunction of the PI system in membrane trafficking.

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Phosphoinositides in cell regulation and membrane dynamics

31 March 2020

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Role of Rab GTPases in membrane traffic and cell physiology

31 March 2020

1 reference

Mammalian phosphoinositide kinases and phosphatases

31 March 2020

1 reference

Membrane recognition by phospholipid-binding domains

31 March 2020

1 reference

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

31 March 2020

1 reference

Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11

31 March 2020

1 reference

31 March 2020

1 reference

The regulation and function of Class III PI3Ks: novel roles for Vps34.

31 March 2020

1 reference

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

31 March 2020

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Rab conversion as a mechanism of progression from early to late endosomes

31 March 2020

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An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

31 March 2020

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A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway

31 March 2020

1 reference

Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast

31 March 2020

1 reference

The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7.

31 March 2020

1 reference

A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function

31 March 2020

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Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase

31 March 2020

1 reference

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse

31 March 2020

1 reference

Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase

31 March 2020

1 reference

The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling

31 March 2020

1 reference

Myotubularin lipid phosphatase binds the hVPS15/hVPS34 lipid kinase complex on endosomes

31 March 2020

1 reference

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

31 March 2020

1 reference

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

31 March 2020

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Human VPS34 and p150 are Rab7 Interacting Partners

31 March 2020

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Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases

31 March 2020

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Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation

31 March 2020

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Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p

31 March 2020

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Requirement of phosphatidylinositol-4,5-bisphosphate for HERC1-mediated guanine nucleotide release from ARF proteins

31 March 2020

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Role of protein-phospholipid interactions in the activation of ARF1 by the guanine nucleotide exchange factor Arno

31 March 2020

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Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis

31 March 2020

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Coincidence detection in phosphoinositide signaling.

31 March 2020

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The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function

31 March 2020

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FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

31 March 2020

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Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

31 March 2020

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The p85alpha subunit of phosphatidylinositol 3'-kinase binds to and stimulates the GTPase activity of Rab proteins

31 March 2020

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Disrupted RabGAP function of the p85 subunit of phosphatidylinositol 3-kinase results in cell transformation.

31 March 2020

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Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

31 March 2020

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Endosomal sorting and signalling: an emerging role for sorting nexins.

31 March 2020

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Characterization of Rab21-positive tubular endosomes induced by PI3K inhibitors.

31 March 2020

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The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes

31 March 2020

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A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

31 March 2020

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The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling

31 March 2020

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TRAPP complexes in membrane traffic: convergence through a common Rab.

31 March 2020

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Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes.

31 March 2020

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Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.

31 March 2020

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A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositides

31 March 2020

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Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis

31 March 2020

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Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

31 March 2020

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Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function

31 March 2020

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Phosphatidylinositol 3,4,5-trisphosphate localization in recycling endosomes is necessary for AP-1B-dependent sorting in polarized epithelial cells

31 March 2020

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Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells

31 March 2020

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Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

31 March 2020

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Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D.

31 March 2020

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Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae

31 March 2020

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The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor

31 March 2020

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PtdIns(4,5)P2 functions at the cleavage furrow during cytokinesis

31 March 2020

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PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

31 March 2020

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Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22722608

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myotubularin phosphoinositide phosphatases: cellular functions and disease pathophysiology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22722608

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22722608

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRM3379

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Dimensions Publication ID

27 August 2017

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