Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials (Q38025153)

27 August 2017

Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials (English)

1 reference

27 August 2017

1 reference

Pamela Maffioli

2

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Giuseppe Derosa

object named as

Giuseppe Derosa

series ordinal

1

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Arrigo F. Cicero

series ordinal

3

object named as

Arrigo F G Cicero

1 reference

PubMed ID

22780092

27 August 2017

language of work or name

English

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publication date

1 August 2012

1 reference

Expert Opinion on Biological Therapy

27 August 2017

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27 August 2017

12

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27 August 2017

8

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27 August 2017

1113-1124

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IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030

27 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

An update on regional variation in cardiovascular mortality within Europe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Standards of medical care in diabetes--2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Meta-analysis of the effect of herbal supplement on glycemic control in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Insulin sensitizing and insulinotropic action of berberine from Cortidis rhizoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Effects of berberine on glucose metabolism in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine promotes glucagon-like peptide-1 (7-36) amide secretion in streptozotocin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Targeting metabolic syndrome: candidate natural agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine acutely inhibits insulin secretion from beta-cells through 3',5'-cyclic adenosine 5'-monophosphate signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine-induced activation of 5'-adenosine monophosphate-activated protein kinase and glucose transport in rat skeletal muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine ameliorates hyperglycemia in alloxan-induced diabetic C57BL/6 mice through activation of Akt signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Traditional chinese medicine in treatment of metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine reverses free-fatty-acid-induced insulin resistance in 3T3-L1 adipocytes through targeting IKKbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine activates GLUT1-mediated glucose uptake in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine improves glucose metabolism through induction of glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine stimulates glucose transport through a mechanism distinct from insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Chronic effects of berberine on blood, liver glucolipid metabolism and liver PPARs expression in diabetic hyperlipidemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine inhibits 3T3-L1 adipocyte differentiation through the PPARgamma pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Effects and action mechanisms of berberine and Rhizoma coptidis on gut microbes and obesity in high-fat diet-fed C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine reduces fibronectin and collagen accumulation in rat glomerular mesangial cells cultured under high glucose condition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Extracellular signal-regulated kinase-dependent stabilization of hepatic low-density lipoprotein receptor mRNA by herbal medicine berberine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine-induced LDLR up-regulation involves JNK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine decreases PCSK9 expression in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Mechanism of the aortic relaxation induced by low concentrations of berberine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Vasorelaxant and antiproliferative effects of berberine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Effects of berberine on angiotensin-converting enzyme and NO/cGMP system in vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Mechanism of vasodilatory effect of berberine in rat mesenteric artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Roles of nitric oxide in protective effect of berberine in ethanol-induced gastric ulcer mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Effect of berberine on catecholamine levels in rats with experimental cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Inhibitory effects of berberine on ATP-sensitive K+ channels in cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Anti-cancer natural products isolated from chinese medicinal herbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Hepatobiliary excretion of berberine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine ameliorates renal injury in diabetic C57BL/6 mice: Involvement of suppression of SphK-S1P signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Efficacy of berberine in patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

A nutraceutical combination improves insulin sensitivity in patients with metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Combination of simvastatin with berberine improves the lipid-lowering efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine-induced mobilization of circulating endothelial progenitor cells improves human small artery elasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine-induced decline in circulating CD31+/CD42- microparticles is associated with improvement of endothelial function in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Effect of berberine on arachidonic acid metabolism in rabbit platelets and endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine, a natural lipid-lowering drug, exerts prothrombotic effects on vascular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Inhibitory effect of berberine on tert-butyl hydroperoxide-induced oxidative damage in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2012.704014

10.1517/14712598.2012.704014

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

22780092