Inactivated virus vaccines from chemistry to prophylaxis: merits, risks and challenges (Q38032879)

27 August 2017

Inactivated virus vaccines from chemistry to prophylaxis: merits, risks and challenges (English)

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27 August 2017

4

Hans J Nauwynck

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27 August 2017

Iris Delrue

1

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PubMed ID

22873127

27 August 2017

Dieter Verzele

series ordinal

2

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PubMed ID

22873127

27 August 2017

Annemieke Madder

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3

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27 August 2017

1 June 2012

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Expert Review of Vaccines

27 August 2017

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27 August 2017

11

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27 August 2017

695-719

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27 August 2017

6

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Integrity of GH-loop of foot-and-mouth disease virus during virus inactivation: detection by epitope specific antibodies

27 August 2017

1 reference

Delipidation of a hepadnavirus: Viral inactivation and vaccine development.

21 January 2018

1 reference

Immune response of chimpanzees after immunization with the inactivated whole immunodeficiency virus (HIV-1), three different adjuvants and challenge

21 January 2018

1 reference

The preclinical testing of a formaldehyde inactivated Ross River virus vaccine designed for use in humans

21 January 2018

1 reference

An inactivated West Nile virus vaccine for domestic geese-efficacy study and a summary of 4 years of field application

21 January 2018

1 reference

Development of a purified, inactivated, dengue-2 virus vaccine prototype in Vero cells: immunogenicity and protection in mice and rhesus monkeys

21 January 2018

1 reference

Efficacy of an inactivated vaccine for equine herpesvirus type 1 in a novel hamster model

21 January 2018

1 reference

Inactivated Hantaan virus vaccine derived from suspension culture of Vero cells

21 January 2018

1 reference

Characterization of an avian influenza virus H5N1 Egyptian isolate.

21 January 2018

1 reference

Intranasal immunization with inactivated tick-borne encephalitis virus and the antigenic peptide 89-119 protects mice against intraperitoneal challenge.

21 January 2018

1 reference

Immunogenicity and protective efficacy in mice of a formaldehyde-inactivated Indian strain of Japanese encephalitis virus grown in Vero cells

21 January 2018

1 reference

Identification of formaldehyde-induced modifications in proteins: reactions with model peptides

21 January 2018

1 reference

Review of the genotoxicity of formaldehyde

21 January 2018

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Aldehyde-induced protein-DNA crosslinks disrupt specific stages of SV40 DNA replication.

21 January 2018

1 reference

Structure and immunogenicity of experimental foot-and-mouth disease and poliomyelitis vaccines

21 January 2018

1 reference

Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV.

21 January 2018

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A double-inactivated whole virus candidate SARS coronavirus vaccine stimulates neutralising and protective antibody responses

21 January 2018

1 reference

Intranasal immunization with inactivated SARS-CoV (SARS-associated coronavirus) induced local and serum antibodies in mice.

21 January 2018

1 reference

Immunopathogenesis of vaccine-enhanced RSV disease.

21 January 2018

1 reference

Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodeficiency virus in a male urethral challenge model

21 January 2018

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Vaccine-induced enhancement of viral infections.

21 January 2018

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21 January 2018

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Formalin-inactivated bovine RSV vaccine enhances a Th2 mediated immune response in infected cattle.

21 January 2018

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Effect of virus-specific antibodies on attachment, internalization and infection of porcine reproductive and respiratory syndrome virus in primary macrophages

21 January 2018

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Assessing the functionality of viral entry-associated domains of porcine reproductive and respiratory syndrome virus during inactivation procedures, a potential tool to optimize inactivated vaccines

21 January 2018

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Sites of reaction of glutaraldehyde and acetaldehyde with nucleosides

21 January 2018

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Mechanism of Crosslinking of Proteins by Glutaraldehyde II. Reaction with Monomeric and Polymeric Collagen

21 January 2018

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Glutaraldehyde as a protein cross-linking reagent

21 January 2018

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Vaccination with glutaraldehyde-fixed bovine respiratory syncytial virus (BRSV)-infected cells stimulates a better immune response in lambs than vaccination with heat-inactivated cell-free BRSV.

21 January 2018

1 reference

Fluorescence spectroscopy monitoring of the conformational restraint of formaldehyde- and glutaraldehyde-treated infectious bursal disease virus proteins

21 January 2018

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The cotton rat model of respiratory viral infections

21 January 2018

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Sites, Mechanism of Action and Lack of Reversibility of Primate Lentivirus Inactivation by Preferential Covalent Modification of Virion Internal Proteins

21 January 2018

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Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages

21 January 2018

1 reference

Evaluation of the safety, immunogenicity, and protective efficacy of whole inactivated simian immunodeficiency virus (SIV) vaccines with conformationally and functionally intact envelope glycoproteins

21 January 2018

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Tonsillar application of AT-2 SIV affords partial protection against rectal challenge with SIVmac239.

21 January 2018

1 reference

Inactivation of DNA by beta-propiolactone

21 January 2018

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Reactions of beta-propiolactone with nucleobase analogues, nucleosides, and peptides: implications for the inactivation of viruses

21 January 2018

1 reference

Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface

21 January 2018

1 reference

Influenza virus inactivation for studies of antigenicity and phenotypic neuraminidase inhibitor resistance profiling

21 January 2018

1 reference

An inactivated cell-culture vaccine against yellow fever

21 January 2018

1 reference

Immunogenicity and protective efficacy in mice and hamsters of a β-propiolactone inactivated whole virus SARS-CoV vaccine

21 January 2018

1 reference

A single immunization with CoVaccine HT-adjuvanted H5N1 influenza virus vaccine induces protective cellular and humoral immune responses in ferrets

21 January 2018

1 reference

A new Vero cell rabies vaccine: results of a comparative trial with human diploid cell rabies vaccine in children

21 January 2018

1 reference

Inactivated infectious haematopoietic necrosis virus (IHNV) vaccines

21 January 2018

1 reference

Binary ethylenimine as an inactivant for foot-and-mouth disease virus and its application for vaccine production

21 January 2018

1 reference

Inactivation of viral antigens for vaccine preparation with particular reference to the application of binary ethylenimine

21 January 2018

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Viral capsid mobility: a dynamic conduit for inactivation.

21 January 2018

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Biologically relevant chemical reactions of N7-alkylguanine residues in DNA.

21 January 2018

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A candidate Ross River virus vaccine: preclinical evaluation

21 January 2018

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An experimental chemically inactivated HIV-1 vaccine induces antibodies that neutralize homologous and heterologous viruses

21 January 2018

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Production and characterization of monoclonal antibodies against binary ethylenimine inactivated Nipah virus

21 January 2018

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Development of an experimental inactivated PRRSV vaccine that induces virus-neutralizing antibodies

21 January 2018

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Inactivation of 12 viruses by heating steps applied during manufacture of a hepatitis B vaccine.

21 January 2018

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Virus inactivation of plasma-derived proteins by pasteurization in the presence of guanidine hydrochloride

21 January 2018

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Thermal Inactivation of Semliki Forest Virus

21 January 2018

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Differences between the thermal inactivation of picornaviruses at "high" and "low" temperatures.

21 January 2018

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Thermal Inactivation Studies of a Coronavirus, Transmissible Gastroenteritis Virus

21 January 2018

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Induction of humoral immune responses following vaccination with envelope-containing, formaldehyde-treated, thermally inactivated human immunodeficiency virus type 1.

21 January 2018

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UV-induced DNA damage and repair: a review

21 January 2018

1 reference

Gene and transcription unit mapping by radiation effects

21 January 2018

1 reference

Exposure of rabbits to ultraviolet light-inactivated rabbit haemorrhagic disease virus (RHDV) and subsequent challenge with virulent virus

21 January 2018

1 reference

Ultraviolet-light-inactivated Cas-Br-M murine leukemia virus induces a protective CD8+ cytotoxic T lymphocyte response in newborn mice

21 January 2018

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Effective use of gamma irradiation for pathogen inactivation of monoclonal antibody preparations

21 January 2018

1 reference

Inactivated Lassa virus elicits a non protective immune response in rhesus monkeys

21 January 2018

1 reference

Standardization of an Inactivated H7N1 Avian Influenza Vaccine and Efficacy Against A/Chicken/Italy/13474/99 High-Pathogenicity Virus Infection

21 January 2018

1 reference

Enhanced binding of antibodies to neutralization epitopes following thermal and chemical inactivation of human immunodeficiency virus type 1.

21 January 2018

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Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein

21 January 2018

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Neutralizing ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against it

21 January 2018

1 reference

Molecular mass and volume in radiation target theory

21 January 2018

1 reference

Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment

21 January 2018

1 reference

Kinetics of RNA Degradation by Specific Base Catalysis of Transesterification Involving the 2‘-Hydroxyl Group

21 January 2018

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Biochemical identification of viruses causing the 1981 outbreaks of foot and mouth disease in the UK

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERV.12.38

1 reference

27 August 2017

1 reference

PubMed ID

22873127