Risk assessment for aflatoxin: I. Metabolism of aflatoxin B1 by different species (Q38033337)

27 August 2017

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title

Risk assessment for aflatoxin: I. Metabolism of aflatoxin B1 by different species (English)

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27 August 2017

Gorelick NJ

1

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27 August 2017

1 December 1990

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27 August 2017

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27 August 2017

10

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27 August 2017

539-559

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27 August 2017

4

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The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

27 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Mutagenic activation of aflatoxin B1 by P-450 HFLa in human fetal livers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Isolation and characterization of human fetal liver cytochrome P450HLp2: a third member of the P450III gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Measurement of urinary 6-?-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Nifedipine: variability in its kinetics and metabolism in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Isolation of a new human fetal liver cytochrome P450 cDNA clone: evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Purification and properties of cytochrome P-450 from homogenates of human fetal livers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Molecular genetics of the P-450 superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Immunochemical evidence for multiple steroid-inducible hepatic cytochromes P-450 in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Hepatic microsomal mixed function oxygenase: enzyme multiplicity for the metabolism of carcinogens to DNA-binding metabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Mutagenic activation of aflatoxin B1 by several forms of purified cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Cytochrome P-450-mediated activation of procarcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/pSK1002.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Genotoxic and mutagenic activation of aflatoxin B1 by constitutive forms of cytochrome P-450 in rat liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Purification and characterization of a form of cytochrome P-450 with high specificity for aflatoxin B1 from 3-methylcholanthrene-treated hamster liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Complete cDNA sequence of a major 3-methylcholanthrene-inducible cytochrome P-450 isozyme (P-450AFB) of Syrian hamsters with high activity toward aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Aflatoxin B1-specific cytochrome P-450 isozyme (P-450-AFB) inducible by 3-methylcholanthrene in golden hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Mutagenicity of aflatoxin B1, activated by S-9 fractions of human, rat; mouse, rabbit, and monkey liver, towards s. typhimurium TA 98

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The requirement for glutathione S-transferase in the conjugation of activated aflatoxin B1 during aflatoxin hepatocarcinogenesis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Effects of single-dose and repeated-dose pretreatment with 2(3)-tert-butyl-4-hydroxyanisole (BHA) on the hepatobiliary disposition and covalent binding to DNA of aflatoxin B1 in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Comparative effects of butylated hydroxyanisole on hepatic in vivo DNA binding and in vitro biotransformation of aflatoxin B1 in the rat and mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Effects of modulation of hepatic glutathione on biotransformation and covalent binding of aflatoxin B1 to DNA in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Conjugation of model substrates or microsomally-activated aflatoxin B1 with reduced glutathione, catalysed by cytosolic glutathione-S-transferases in livers of rats, mice and guinea pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The metabolism of aflatoxin B1 by human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Metabolic basis of the species difference to aflatoxin B1 induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Characterization of water-soluble glucuronide and sulphate conjugates of aflatoxin B1. 1. Urinary excretion in monkey, rat and mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Excretion and metabolism of orally administered aflatoxin B1 by rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Carcinogenicity of synthetic aflatoxin M1 in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Effects of phenobarbital pretreatment on the metabolism and toxicokinetics of aflatoxin B1 in the rhesus monkey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Cell and species differences in metabolic activation of chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Effect of caloric restriction on aflatoxin B1-DNA adduct formation and associated factors in Fischer 344 rats: preliminary findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Modification by beet and cabbage diets of aflatoxin B1-induced rat plasma α-foetoprotein elevation, hepatic tumorigenesis, and mutagenicity of urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The effects of dietary cabbage on xenobiotic-metabolizing enzymes and the binding of aflatoxin B1 to hepatic DNA in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Modifying role of dietary factors on the mutagenicity of aflatoxin B1: in vitro effect of plant flavonoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Partial purification and properties of cytochrome P450 from homogenates of human fetal livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Aflatoxin M1 in Human Urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Interactions of aflatoxin B1 and alkylating agents with DNA: structural and functional studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Significance of cytochrome P-450 (P-450 HFLa) of human fetal livers in the steroid and drug oxidations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Multiplicity of steroid-inducible cytochromes P-450 in rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Evidence for functional and structural multiplicity of pregnenolone-16 alpha-carbonitrile-inducible cytochrome P-450 isozymes in rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Regulation of cytochrome P-450p by phenobarbital and phenobarbital-like inducers in adult rat hepatocytes in primary monolayer culture and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Characterization of a phenobarbital-inducible dog liver cytochrome P450 structurally related to rat and human enzymes of the P450IIIA (steroid-inducible) gene subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

A comparison of the effects of pretreatment with phenobarbitone and 3-methylcholanthrene on the metabolism of aflatoxin B1 by rat liver microsomes and isolated hepatocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Purification and characterization of a hepatic mitochondrial cytochrome P-450 active in aflatoxin B1 metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Sex differences in cytochrome P-450 isozyme composition and activity in kidney microsomes of mature rainbow trout

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Reduction III binding of [14C] aflatoxin B1 to rat liver macromolecules by phenobarbitone pretreatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The major metabolite of aflatoxin B1 in the rat is a glutathione conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The inhibitory effects of ethoxyquin on the carcinogenic action of aflatoxin B1 in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Urinary excretion of thiol conjugates of aflatoxin B1 in rats and hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Effect of purified rat and hamster hepatic glutathione S-transferases on the microsome mediated binding of aflatoxin B1 to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The comparative metabolism and toxicokinetics of aflatoxin B1 in the monkey, rat, and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Human aflatoxin B1 metabolism: an investigation of the importance of aflatoxin Q1 as a metabolite of hepatic post-mitochondrial fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Comparison of metabolic activation of carcinogens in human, rat, and hamster hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

The effect of protein deficiency on the in vivo binding of aflatoxin B1 to rat liver macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Modulation by some natural carotenoids of DNA adduct formation by aflatoxin B1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

Immunochemical similarity of P-450 HFLa, a form of cytochrome P-450 in human fetal livers, to a form of rat liver cytochrome P-450 inducible by macrolide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1539-6924.1990.TB00538.X

10.1111/J.1539-6924.1990.TB00538.X

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference

PubMed ID

2287782