Epigenetic-dependent regulation of drug transport and metabolism: an update (Q38042440)

27 August 2017

Epigenetic-dependent regulation of drug transport and metabolism: an update (English)

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27 August 2017

Magnus Ingelman-Sundberg

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3

object named as

Magnus Ingelman-Sundberg

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Marina Kacevska

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1

object named as

Marina Kacevska

1 reference

27 August 2017

Maxim Ivanov

2

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27 August 2017

1 September 2012

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27 August 2017

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27 August 2017

13

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27 August 2017

12

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27 August 2017

1373-1385

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Chromatin modifications and their function

27 August 2017

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

CpG islands and the regulation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

An evaluation of new criteria for CpG islands in the human genome as gene markers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

5-Hydroxymethylcytosine, the sixth base of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Distribution of 5-hydroxymethylcytosine in different human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

The ENCODE (ENCyclopedia Of DNA Elements) Project

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Non-coding RNAs in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Interplay between microRNAs and the epigenetic machinery: an intricate network

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

No-nonsense functions for long noncoding RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Cooperation between complexes that regulate chromatin structure and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

RNA-protein interactions in human health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Evolutionary diversity and developmental regulation of X-chromosome inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Long noncoding RNA as modular scaffold of histone modification complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Non-coding RNAs, epigenetic memory and the passage of information to progeny

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Modular regulatory principles of large non-coding RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

RNA traffic control of chromatin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Perspectives on epigenetics and its relevance to adverse drug reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

In utero tobacco exposure epigenetically modifies placental CYP1A1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Cytochrome P450 2E1 in the substantia nigra: relevance for dopaminergic neurotransmission and free radical production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

P450 enzymes and Parkinson's disease: the story so far.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Histone deacetylase 1 is required for Carbamazepine-induced CYP3A4 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

In silico identification of microRNAs predicted to regulate the drug metabolizing cytochrome P450 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Toxicological implications of modulation of gene expression by microRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNAs from biology to future pharmacotherapy: regulation of cytochrome P450s and nuclear receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA pharmacogenomics: post-transcriptional regulation of drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

The non-coding Air RNA is required for silencing autosomal imprinted genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Epigenetic and copy number variation analysis in retinoblastoma by MS-MLPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

GSTP1 hypermethylation is associated with reduced protein expression, aggressive disease and prognosis in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Multigene methylation analysis for detection and staging of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Reduction of GSTP1 expression by DNA methylation correlates with clinicopathological features in pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Role of glutathione-S-transferase P1 hypermethylation in molecular detection of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Expression of genes for redox-dependent glutathione S-transferase isoforms GSTP1-1 and GSTA4-4 in tumor cell during the development doxorubicin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Glutathione peroxidases in different stages of carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

p53-induced gene 3 mediates cell death induced by glutathione peroxidase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Hypermethylation and loss of expression of glutathione peroxidase-3 in Barrett's tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

DNA methylation-related vitamin D receptor insensitivity in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Mechanisms of chemotherapeutic drug resistance in cancer therapy--a quick review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MDR1, chemotherapy and chromatin remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

DNA-methylation profiling distinguishes malignant melanomas from benign nevi

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Methylation of the human pendrin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Pharmacogenetics and pharmacoepigenetics of gemcitabine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Epigenetic differences in normal colon mucosa of cancer patients suggest altered dietary metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Aberrant methylation of RARbeta2 and APC genes in voided urine as molecular markers for early detection of bilharzial and nonbilharzial bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA regulates the expression of human cytochrome P450 1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Human CYP2E1 is regulated by miR-378.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MiR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNAs play a role in the development of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

MicroRNA-92b regulates expression of the oligopeptide transporter PepT1 in intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.119

21 January 2018

Identifiers

DOI

10.2217/PGS.12.119

1 reference

27 August 2017

1 reference

PubMed ID

22966887