MicroRNAs, transforming growth factor beta-1, and tissue fibrosis. (Q38050081)

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10 March 2020

title

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis (English)

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10 March 2020

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2

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10 March 2020

Donald J Fraser

series ordinal

3

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10 March 2020

author name string

Timothy Bowen

series ordinal

1

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10 March 2020

publication date

29 November 2012

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10 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23042530%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

229

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10 March 2020

issue

2

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10 March 2020

page(s)

274-285

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Initial impact of the sequencing of the human genome

10 March 2020

cites work

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

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Gene regulation by transcription factors and microRNAs

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Most mammalian mRNAs are conserved targets of microRNAs

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Transcription factors are targeted by differentially expressed miRNAs in primates

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Natural antisense mRNAs to hyaluronan synthase 2 inhibit hyaluronan biosynthesis and cell proliferation

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The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell

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The extracellular matrix: an active or passive player in fibrosis?

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Fibroblasts and myofibroblasts in renal fibrosis

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MicroRNA evolution by arm switching

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The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay

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Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish

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miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay

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Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells

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Cytoplasmic ribonucleoprotein (RNP) bodies and their relationship to GW/P bodies

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GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation

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P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

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Formation of GW bodies is a consequence of microRNA genesis

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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

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Role of transforming growth factor-beta superfamily signaling pathways in human disease

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

21 January 2018

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Smad transcription factors

21 January 2018

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Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells

21 January 2018

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Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-beta 1 synthesis via an autocrine PDGF loop

21 January 2018

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Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor

21 January 2018

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ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells.

21 January 2018

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Y-box protein-1 controls transforming growth factor-beta1 translation in proximal tubular cells

21 January 2018

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A conserved stem loop motif in the 5'untranslated region regulates transforming growth factor-β(1) translation

21 January 2018

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Post-transcriptional regulation of Transforming Growth Factor Beta-1 by microRNA-744

21 January 2018

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Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD

21 January 2018

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The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

21 January 2018

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The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

21 January 2018

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

21 January 2018

1 reference

MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: a novel role of miR-382.

21 January 2018

1 reference

Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation

21 January 2018

1 reference

SMAD proteins control DROSHA-mediated microRNA maturation

21 January 2018

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Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

21 January 2018

1 reference

The basics of epithelial-mesenchymal transition

21 January 2018

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Epithelial-mesenchymal transition and its implications for fibrosis

21 January 2018

1 reference

E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta

21 January 2018

1 reference

Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy

21 January 2018

1 reference

p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

21 January 2018

1 reference

Micro-RNA-21 regulates TGF-β-induced myofibroblast differentiation by targeting PDCD4 in tumor-stroma interaction

21 January 2018

1 reference

miR-29 is a major regulator of genes associated with pulmonary fibrosis.

21 January 2018

1 reference

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis

21 January 2018

1 reference

Roles of microRNA-29a in the antifibrotic effect of farnesoid X receptor in hepatic stellate cells

21 January 2018

1 reference

MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis

21 January 2018

1 reference

Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132

21 January 2018

1 reference

Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations.

21 January 2018

1 reference

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

21 January 2018

1 reference

A mammalian microRNA expression atlas based on small RNA library sequencing

21 January 2018

1 reference

MicroRNA-155 is induced during the macrophage inflammatory response

21 January 2018

1 reference

miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate

21 January 2018

1 reference

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway.

21 January 2018

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A microRNA signature of hypoxia

21 January 2018

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Role of microRNAs in kidney homeostasis and disease

21 January 2018

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MicroRNAs and the glomerulus

21 January 2018

1 reference

Translational study of microRNAs and its application in kidney disease and hypertension research

21 January 2018

1 reference

The long and short of microRNAs in the kidney

21 January 2018

1 reference

Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease

21 January 2018

1 reference

Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis

21 January 2018

1 reference

Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury

21 January 2018

1 reference

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy

21 January 2018

1 reference

The microRNA-processing enzyme dicer maintains juxtaglomerular cells

21 January 2018

1 reference

Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury.

21 January 2018

1 reference

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney

21 January 2018

1 reference

The pro-apoptotic protein Bim is a microRNA target in kidney progenitors

21 January 2018

1 reference

MicroRNA-target pairs in the rat kidney identified by microRNA microarray, proteomic, and bioinformatic analysis

21 January 2018

1 reference

miR-200a Prevents renal fibrogenesis through repression of TGF-β2 expression

21 January 2018

1 reference

miR-200b precursor can ameliorate renal tubulointerstitial fibrosis

21 January 2018

1 reference

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

21 January 2018

1 reference

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

21 January 2018

1 reference

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

21 January 2018

1 reference

Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy

21 January 2018

1 reference

Pleiotropy of microRNA-192 in the kidney.

21 January 2018

1 reference

Regulation of WNK1 Expression by miR-192 and Aldosterone

21 January 2018

1 reference

Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity

21 January 2018

1 reference

MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways

21 January 2018

1 reference

Identification of a microRNA signature in renal fibrosis: role of miR-21.

21 January 2018

1 reference

miR-21 and miR-214 are consistently modulated during renal injury in rodent models

21 January 2018

1 reference

MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes

21 January 2018

1 reference

MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice

21 January 2018

1 reference

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

21 January 2018

1 reference

Renal medullary microRNAs in Dahl salt-sensitive rats: miR-29b regulates several collagens and related genes

21 January 2018

1 reference

TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29

21 January 2018

1 reference

MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy

21 January 2018

1 reference

Conditional dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling

21 January 2018

1 reference

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

21 January 2018

1 reference

MicroRNAs play an essential role in the development of cardiac hypertrophy

21 January 2018

1 reference

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

21 January 2018

1 reference

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

21 January 2018

1 reference

miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling

21 January 2018

1 reference

MiR-133a regulates collagen 1A1: potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension

21 January 2018

1 reference

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

21 January 2018

1 reference

MicroRNA-24 regulates cardiac fibrosis after myocardial infarction

21 January 2018

1 reference

MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-β1 pathway.

21 January 2018

1 reference

Pathogenesis of liver fibrosis

21 January 2018

1 reference

The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families

21 January 2018

1 reference

MicroRNAs in liver disease.

21 January 2018

1 reference

Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways

21 January 2018

1 reference

Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation

21 January 2018

1 reference

Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis

21 January 2018

1 reference

Suppression of hepatic stellate cell activation by microRNA-29b.

21 January 2018

1 reference

Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells

21 January 2018

1 reference

miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis

21 January 2018

1 reference

MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4.

21 January 2018

1 reference

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

21 January 2018

1 reference

miR-29 inhibits bleomycin-induced pulmonary fibrosis in mice.

21 January 2018

1 reference

Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactions

21 January 2018

1 reference

Participation of miR-200 in pulmonary fibrosis

21 January 2018

1 reference

Inhibition and role of let-7d in idiopathic pulmonary fibrosis

21 January 2018

1 reference

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

21 January 2018

1 reference

Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition.

21 January 2018

1 reference

HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition

21 January 2018

1 reference

MicroRNA-29, a key regulator of collagen expression in systemic sclerosis

21 January 2018

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MicroRNA expression abnormalities in limited cutaneous scleroderma and diffuse cutaneous scleroderma

21 January 2018

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miR-196a downregulation increases the expression of type I and III collagens in keloid fibroblasts

21 January 2018

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Analysis of microRNA turnover in mammalian cells following Dicer1 ablation.

21 January 2018

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Circulating microRNAs as stable blood-based markers for cancer detection

21 January 2018

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A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer

21 January 2018

1 reference

Validation of the isolation and quantification of kidney enriched miRNAs for use as biomarkers.

21 January 2018

1 reference

Analysis of urinary microRNAs in chronic kidney disease.

21 January 2018

1 reference

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

21 January 2018

1 reference