Inhibition of GTRAP3-18 may increase neuroprotective glutathione (GSH) synthesis (Q38056497)

27 August 2017

9 references

25 April 2019

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3 August 2019

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29 April 2021

Inhibition of GTRAP3-18 may increase neuroprotective glutathione (GSH) synthesis (English)

1 reference

intracellular signaling peptides and proteins

27 August 2017

5 references

25 April 2019

20 June 2019

3 August 2019

12 September 2019

12 October 2019

1 reference

3 August 2019

1 reference

12 September 2019

1 reference

12 October 2019

1 reference

20 November 2019

1 reference

23 January 2021

neuroprotective agent

1 reference

26 January 2021

1 reference

29 April 2021

1 reference

Koji Aoyama

1

1 reference

27 August 2017

Toshio Nakaki

series ordinal

2

1 reference

27 August 2017

language of work or name

English

0 references

publication date

20 September 2012

10 references

International Journal of Molecular Sciences

27 August 2017

25 April 2019

20 June 2019

3 August 2019

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12 October 2019

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23 January 2021

26 January 2021

29 April 2021

10 references

27 August 2017

25 April 2019

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13

1 reference

27 August 2017

9

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27 August 2017

12017-12035

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Creative Commons Attribution 3.0 Unported

27 August 2017

9 references

25 April 2019

20 June 2019

3 August 2019

12 September 2019

12 October 2019

20 November 2019

23 January 2021

26 January 2021

on focus list of Wikimedia project

29 April 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

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6 September 2017

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Nitric oxide and peroxynitrite in health and disease

6 September 2017

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The effects of stress and aging on glutathione metabolism

6 September 2017

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Vitamin E and donepezil for the treatment of mild cognitive impairment

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S-glutathionylation: from redox regulation of protein functions to human diseases.

6 September 2017

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Oxidative stress in Parkinson's disease

6 September 2017

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Methyl-beta-cyclodextrin but not retinoic acid reduces EAAT3-mediated glutamate uptake and increases GTRAP3-18 expression

6 September 2017

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Identification of addicsin/GTRAP3-18 as a chronic morphine-augmented gene in amygdala

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Mechanisms of L-cysteine neurotoxicity

6 September 2017

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Long-term regulation of neuronal high-affinity glutamate and glutamine uptake in Aplysia

6 September 2017

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Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

6 September 2017

1 reference

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Glutathione, oxidative stress and neurodegeneration

6 September 2017

1 reference

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Metabolism and functions of glutathione in brain.

6 September 2017

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Glutamate transporters in kidney and brain

6 September 2017

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Introduction: glutamate transport, metabolism, and physiological responses

6 September 2017

1 reference

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Regulation of membrane trafficking: structural insights from a Rab/effector complex

6 September 2017

1 reference

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Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters

6 September 2017

1 reference

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Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

6 September 2017

1 reference

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Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

6 September 2017

1 reference

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Interaction of L-cysteine with a human excitatory amino acid transporter

6 September 2017

1 reference

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Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease

6 September 2017

1 reference

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Glutathione-ascorbic acid antioxidant system in animals.

6 September 2017

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Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

6 September 2017

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Localization of neuronal and glial glutamate transporters

6 September 2017

1 reference

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Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations

6 September 2017

1 reference

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Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

6 September 2017

1 reference

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6 September 2017

1 reference

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6 September 2017

1 reference

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Glutathione deficiency leads to mitochondrial damage in brain

6 September 2017

1 reference

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Alpha-tocopherol levels in brain are not altered in Parkinson's disease

6 September 2017

1 reference

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JWA regulates chronic morphine dependence via the delta opioid receptor

6 September 2017

1 reference

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Regulation of glutathione synthesis via interaction between glutamate transport-associated protein 3-18 (GTRAP3-18) and excitatory amino acid carrier-1 (EAAC1) at plasma membrane

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

A dominant-negative variant of SNAP-23 decreases the cell surface expression of the neuronal glutamate transporter EAAC1 by slowing constitutive delivery

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Rapid trafficking of the neuronal glutamate transporter, EAAC1: evidence for distinct trafficking pathways differentially regulated by protein kinase C and platelet-derived growth factor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Oxidative damage in neurodegenerative disease

14 September 2017

1 reference

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Oxidative stress, glutamate, and neurodegenerative disorders

14 September 2017

1 reference

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Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury

14 September 2017

1 reference

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Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK).

14 September 2017

1 reference

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Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma.

28 September 2017

1 reference

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Immunohistochemical localization of the neuron-specific glutamate transporter EAAC1 (EAAT3) in rat brain and spinal cord revealed by a novel monoclonal antibody

28 September 2017

1 reference

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Rab3A small GTP-binding protein in Ca(2+)-dependent exocytosis

28 September 2017

1 reference

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Complex roles of glutamate in the Gibbs-Ng model of one-trial aversive learning in the new-born chick.

28 September 2017

1 reference

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Cellular cholesterol efflux mediated by cyclodextrins

28 September 2017

1 reference

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EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[a]pyrene and hydrogen peroxide

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Expressions of JWA protein and heat stress protein 70 induced by cell differentiation inducers combined with heat stress in K562 cells

23 June 2018

1 reference

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Modulation by cellular cholesterol of gene transcription via the cyclic AMP response element

23 June 2018

1 reference

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Pharmacological interference with glutamate re-uptake impairs long-term memory in the honeybee, apis mellifera.

23 June 2018

1 reference

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Brain gamma-glutamyl cysteine synthetase (GCS) mRNA expression patterns correlate with regional-specific enzyme activities and glutathione levels

23 June 2018

1 reference

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The glutathione system of peroxide detoxification is less efficient in neurons than in astroglial cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione

23 June 2018

1 reference

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Use of antioxidant supplements and its association with cognitive function in a rural elderly cohort: the MoVIES Project. Monongahela Valley Independent Elders Survey.

23 June 2018

1 reference

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Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cystine

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Multiple roles of glutathione in the central nervous system.

23 June 2018

1 reference

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Alpha-tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: dose-response study and correlations with plasma levels

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Glial contributions to excitatory neurotransmission in cultured hippocampal cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

In vitro effects of N-acetylcysteine on the mutagenicity of direct-acting compounds and procarcinogens

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Distribution of oxidized and reduced forms of glutathione and cysteine in rat plasma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Pharmacokinetics of intravenously administered glutathione in the rat.

23 June 2018

1 reference

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Vitamin E concentrations in human brain of patients with Alzheimer's disease, fetuses with Down's syndrome, centenarians, and controls

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Cholesterol is required for the reconstruction of the sodium- and chloride-coupled, gamma-aminobutyric acid transporter from rat brain.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Blood-brain barrier restriction of peptides and the low uptake of enkephalins

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

A dominant role of GTRAP3-18 in neuronal glutathione synthesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Protective effect of N-acetyl-L-cysteine on amyloid beta-peptide-induced learning and memory deficits in mice

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Systemic administration of N-acetylcysteine protects dopaminergic neurons against 6-hydroxydopamine-induced degeneration.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Cysteine-induced hypoglycemic brain damage: an alternative mechanism to excitotoxicity

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

The mechanism of JWA gene involved in oxidative stress of cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Long-term neurobehavioral and histological damage in brain of mice induced by L-cysteine

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Glutathione reductase from bovine brain

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Long-term potentiation and contextual fear conditioning increase neuronal glutamate uptake.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Cellular and synaptic localization of the neuronal glutamate transporters excitatory amino acid transporter 3 and 4.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

N-acetylcysteine protects against age-related increase in oxidized proteins in mouse synaptic mitochondria

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Brain glutamate transporter proteins form homomultimers

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Protection by vitamin E selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q, beta-carotene, canthaxanthin, and (+)-catechin against oxidative damage to liver slices measured by oxidized heme proteins

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472789

Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death

31 August 2018

1 reference

12 December 2020

Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases

1 reference

12 December 2020

Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter

1 reference

12 December 2020

Ascorbate in healthy subjects, amyotrophic lateral sclerosis and Alzheimer's disease

1 reference

12 December 2020

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione

1 reference

12 December 2020

The level and half-life of glutathione in human plasma

1 reference

12 December 2020

Drug-induced lipid peroxidation in mice--III. Glutathione content of liver, kidney and spleen after intravenous administration of free and liposomally entrapped glutathione

1 reference

12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

12 December 2020

Protein prenylation: a mediator of protein-protein interactions

1 reference

12 December 2020

Ascorbic acid in the brain

1 reference

12 December 2020

Nigral dopaminergic cell loss in vitamin E deficient rats

1 reference

12 December 2020

Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study

1 reference

12 December 2020

Astrocytes protect neurons from hydrogen peroxide toxicity

1 reference

12 December 2020

Neurotoxicity of cysteine: interaction with glutamate

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS130912017

1 reference

27 August 2017

1 reference

27 August 2017

PubMed publication ID

23109897

1 reference