Systems genetics in "-omics" era: current and future development (Q38058727)

27 August 2017

title

Systems genetics in "-omics" era: current and future development (English)

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27 August 2017

Hong Li

1

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27 August 2017

language of work or name

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9 November 2012

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27 August 2017

published in

Theory in Biosciences

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27 August 2017

volume

132

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27 August 2017

issue

1

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27 August 2017

page(s)

1-16

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Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche

21 January 2018

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Mapping genetically compensatory pathways from synthetic lethal interactions in yeast

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

21 January 2018

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Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors

21 January 2018

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Systems genetics can provide new insights in to immune regulation and autoimmunity.

21 January 2018

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ProDiGe: Prioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples

21 January 2018

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21 January 2018

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A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis

21 January 2018

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PINTA: a web server for network-based gene prioritization from expression data

21 January 2018

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Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation

21 January 2018

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Next-generation genetics in plants

21 January 2018

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Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies.

21 January 2018

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dSLAM analysis of genome-wide genetic interactions in Saccharomyces cerevisiae

21 January 2018

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An Integrative Multi-Network and Multi-Classifier Approach to Predict Genetic Interactions

21 January 2018

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Loss of the Protein‐Tyrosine Phosphatase DEP‐1/PTPRJ Drives Meningioma Cell Motility

21 January 2018

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Heritability and tissue specificity of expression quantitative trait loci

21 January 2018

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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

21 January 2018

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Comprehensive analysis of Arabidopsis expression level polymorphisms with simple inheritance

21 January 2018

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Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome

21 January 2018

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Gain and loss of phosphorylation sites in human cancer

21 January 2018

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Using biological knowledge to uncover the mystery in the search for epistasis in genome-wide association studies

21 January 2018

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Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases

21 January 2018

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Genetics of global gene expression

21 January 2018

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TOM: a web-based integrated approach for identification of candidate disease genes

21 January 2018

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Towards a proteome-scale map of the human protein–protein interaction network

21 January 2018

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A two-platform design for next generation genome-wide association studies

21 January 2018

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Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability

21 January 2018

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Mapping the genetic architecture of gene expression in human liver

21 January 2018

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Large-scale copy number polymorphism in the human genome

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Uncovering the hidden geometry behind metabolic networks.

21 January 2018

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In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants

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Characterization of a recurrent 15q24 microdeletion syndrome.

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Moving toward a system genetics view of disease

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Copy number variant detection in inbred strains from short read sequence data

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Imaging protein-protein interactions inside living cells via interaction-dependent fluorophore ligation.

21 January 2018

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Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies

21 January 2018

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A human protein-protein interaction network: a resource for annotating the proteome

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21 January 2018

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https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Progress and promise of genome-wide association studies for human complex trait genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

High-resolution genetic mapping using the Mouse Diversity outbred population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

An integrated approach to characterize genetic interaction networks in yeast metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

DAnCER: disease-annotated chromatin epigenetics resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Fine-scale structural variation of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Bioinformatics methods for identifying candidate disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Interpretation of association signals and identification of causal variants from genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Linking metabolic QTLs with network and cis-eQTLs controlling biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Genome-wide association studies and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Synthetic associations created by rare variants do not explain most GWAS results

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Gene set enrichment in eQTL data identifies novel annotations and pathway regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

CNV-seq, a new method to detect copy number variation using high-throughput sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

miREnvironment database: providing a bridge for microRNAs, environmental factors and phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

A new multiple regression approach for the construction of genetic regulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Transcription network construction for large-scale microarray datasets using a high-performance computing approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Understanding quantitative genetics in the systems biology era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Overexpression of a cotton cyclophilin gene (GhCyp1) in transgenic tobacco plants confers dual tolerance to salt stress and Pseudomonas syringae pv. tabaci infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Treatment- and population-dependent activity patterns of behavioral and expression QTLs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

CopyMap: localization and calling of copy number variation by joint analysis of hybridization data from multiple individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

eQTL Viewer: visualizing how sequence variation affects genome-wide transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

The mystery of missing heritability: Genetic interactions create phantom heritability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

System-wide molecular evidence for phenotypic buffering in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Gene expression quantitative trait locus analysis of 16â 000 barley genes reveals a complex pattern of genome-wide transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Building phenotype networks to improve QTL detection: a comparative analysis of fatty acid and fat traits in pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

The genetics of plant metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12064-012-0168-X

Synthetic lethality-based targets for discovery of new cancer therapeutics.

21 January 2018

1 reference

12 December 2020

Genetic risk information for common diseases may indeed be already useful for prevention and early detection

1 reference

12 December 2020

Candidate gene identification approach: progress and challenges

1 reference

12 December 2020

Polygenes, risk prediction, and targeted prevention of breast cancer

1 reference

12 December 2020

Mutation analysis of candidate genes SCN1B, KCND3 and ANK2 in patients with clinical diagnosis of long QT syndrome.

1 reference

12 December 2020

Multifactor dimensionality reduction as a filter-based approach for genome wide association studies

1 reference

12 December 2020

Pinpointing expression differences

1 reference

12 December 2020

Personal genomics: information can be harmful

1 reference

12 December 2020

Targeting Rb inactivation in cancers by synthetic lethality.

1 reference

12 December 2020

Genetic risk prediction--are we there yet?

1 reference

12 December 2020

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes

1 reference

12 December 2020

Statistical methods for expression quantitative trait loci (eQTL) mapping

1 reference

12 December 2020

Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae

1 reference

12 December 2020

Rare variants create synthetic genome-wide associations

1 reference

12 December 2020

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

1 reference

12 December 2020

A semantic web framework to integrate cancer omics data with biological knowledge

1 reference

12 December 2020

Associations of polymorphisms in HPC2/ELAC2 and SRD5A2 genes with benign prostate hyperplasia in Turkish men

1 reference

12 December 2020

10.1007/S12064-012-0168-X

Identifiers

DOI

1 reference

27 August 2017

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

1025321771

0 references

1 reference