Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells (Q38059499)

28 August 2017

title

Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells (English)

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28 August 2017

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28 August 2017

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28 August 2017

Fernando Albericio

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author name string

Luis J Cruz

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1

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28 August 2017

Felix Rueda

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2

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28 August 2017

Paul Tacken

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28 August 2017

publication date

1 October 2012

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28 August 2017

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28 August 2017

volume

7

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28 August 2017

issue

10

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28 August 2017

page(s)

1591-1610

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Uridine metabolism in HIV-1-infected patients: effect of infection, of antiretroviral therapy and of HIV-1/ART-associated lipodystrophy syndrome

28 August 2017

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Induction of protective immune responses against R5 human immunodeficiency virus type 1 (HIV-1) infection in hu-PBL-SCID mice by intrasplenic immunization with HIV-1-pulsed dendritic cells: possible involvement of a novel factor of human CD4(+) T-ce

21 January 2018

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Potent immune response against HIV-1 and protection from virus challenge in hu-PBL-SCID mice immunized with inactivated virus-pulsed dendritic cells generated in the presence of IFN-alpha

21 January 2018

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Therapeutic dendritic-cell vaccine for simian AIDS.

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Priming of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cell responses by dendritic cells loaded with HIV-1 proteins

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21 January 2018

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21 January 2018

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Human dendritic cells are activated by chimeric human papillomavirus type-16 virus-like particles and induce epitope-specific human T cell responses in vitro

21 January 2018

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21 January 2018

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21 January 2018

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Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells

21 January 2018

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Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection

21 January 2018

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GP120-specific exosome-targeted T cell-based vaccine capable of stimulating DC- and CD4(+) T-independent CTL responses

21 January 2018

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Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.

21 January 2018

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HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells

21 January 2018

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21 January 2018

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21 January 2018

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Targeting antigens to dendritic cells in vivo

21 January 2018

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New tools for antigen delivery to the MHC class I pathway

21 January 2018

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OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway

21 January 2018

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

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Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+ CD25+ T cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Engineered antibodies

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Cross-talk between Fc receptors and integrins.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens

21 January 2018

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A bispecific antibody composed of a nonneutralizing antibody to the gp41 immunodominant region and an anti-CD89 antibody directs broad human immunodeficiency virus destruction by neutrophils

21 January 2018

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Utilization of immunoglobulin G Fc receptors by human immunodeficiency virus type 1: a specific role for antibodies against the membrane-proximal external region of gp41.

21 January 2018

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An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants

21 January 2018

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An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery

21 January 2018

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Engineered lentivector targeting of dendritic cells for in vivo immunization

21 January 2018

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On the role of the SP1 domain in HIV-1 particle assembly: a molecular switch?

21 January 2018

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Immunogenicity and effect of a virosomal influenza vaccine on viral replication and T-cell activation in HIV-infected children receiving highly active antiretroviral therapy

21 January 2018

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Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice

21 January 2018

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DC-SIGN mediated antigen-targeting using glycan-modified liposomes: formulation considerations

21 January 2018

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Immunization with a soluble recombinant HIV protein entrapped in biodegradable microparticles induces HIV-specific CD8+ cytotoxic T lymphocytes and CD4+ Th1 cells.

21 January 2018

1 reference

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Polyelectrolyte capsules-containing HIV-1 p24 and poly I:C modulate dendritic cells to stimulate HIV-1-specific immune responses.

21 January 2018

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Gold nanoparticles coated with oligomannosides of HIV-1 glycoprotein gp120 mimic the carbohydrate epitope of antibody 2G12.

21 January 2018

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TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses

21 January 2018

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Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

21 January 2018

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Programming the magnitude and persistence of antibody responses with innate immunity

21 January 2018

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Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity

21 January 2018

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Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

21 January 2018

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Mechanism of T cell exhaustion in a chronic environment

21 January 2018

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Chronically HIV-1 Infected Patients Exhibit Low Frequencies of CD25+ Regulatory T Cells.

21 January 2018

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Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism

21 January 2018

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Preserved function of regulatory T cells in chronic HIV-1 infection despite decreased numbers in blood and tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy

21 January 2018

1 reference

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Memory and naive-like regulatory CD4+ T cells expand during HIV-2 infection in direct association with CD4+ T-cell depletion irrespectively of viremia.

21 January 2018

1 reference

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Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease

21 January 2018

1 reference

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In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

Protective HIV-specific CD8+ T cells evade Treg cell suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

Human immunodeficiency virus type 1 Nef in human monocyte-like cell line THP-1 expands treg cells via toll-like receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

Longitudinal changes of peripheral blood DC subsets and regulatory T cells in Chinese chronic HIV-1-infected patients during antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

Immunotherapy of murine retrovirus-induced acquired immunodeficiency by CD4 T regulatory cell depletion and PD-1 blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

The combination of 4-1BBL and CD40L strongly enhances the capacity of dendritic cells to stimulate HIV-specific T cell responses

21 January 2018

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Regulatory T cells in HIV immunotherapy

21 January 2018

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Dendritic cell-based human immunodeficiency virus vaccine

21 January 2018

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A phase I/IIa immunotherapy trial of HIV-1-infected patients with Tat, Rev and Nef expressing dendritic cells followed by treatment interruption

21 January 2018

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DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation

21 January 2018

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Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a ‘high-affinity’ FcγRIIa genotype

21 January 2018

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Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro

21 January 2018

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Severe immune dysregulation affects CD4⁺CD25(hi)FoxP3⁺ regulatory T cells in HIV-infected patients with low-level CD4 T-cell repopulation despite suppressive highly active antiretroviral therapy

21 January 2018

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Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells

21 January 2018

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https://api.crossref.org/works/10.2217%2FNNM.12.131

P19-26. Directing macaque immune responses with an anti-dendritic cell HIV Gag p24 fusion protein vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

S04-04 OA. HIV-specific responses induced by anti-CD40 targeting antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

P17-04. Targeting HIV peptides to human dendritic cells via CD40 elicits expansion of multi-epitope polyfunctional CD4+ and CD8+ T cells in HIV patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FNNM.12.131

21 January 2018

Identifiers

DOI

10.2217/NNM.12.131

1 reference

28 August 2017

1 reference