Improving myelin/oligodendrocyte-related dysfunction: a new mechanism of antipsychotics in the treatment of schizophrenia? (Q38060893)

28 August 2017

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title

Improving myelin/oligodendrocyte-related dysfunction: a new mechanism of antipsychotics in the treatment of schizophrenia? (English)

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28 August 2017

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Yuan Ren

1

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28 August 2017

Hanzhi Wang

series ordinal

2

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28 August 2017

Lan Xiao

series ordinal

3

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28 August 2017

language of work or name

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20 November 2012

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The International Journal of Neuropsychopharmacology

28 August 2017

published in

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28 August 2017

volume

16

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28 August 2017

issue

3

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28 August 2017

page(s)

691-700

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Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.

28 August 2017

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Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

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Wnt/beta-catenin signaling is an essential and direct driver of myelin gene expression and myelinogenesis

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Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins.

21 January 2018

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Quetiapine has a direct effect on the negative symptoms of schizophrenia

21 January 2018

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The ErbB4 neuregulin receptor mediates suppression of oligodendrocyte maturation.

21 January 2018

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Prefrontal abnormality of schizophrenia revealed by DNA microarray: impact on glial and neurotrophic gene expression

21 January 2018

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21 January 2018

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Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10

21 January 2018

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Protective effects of haloperidol and clozapine on energy-deprived OLN-93 oligodendrocytes.

21 January 2018

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Reduced density of ADAM 12-immunoreactive oligodendrocytes in the anterior cingulate white matter of patients with schizophrenia

21 January 2018

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Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

21 January 2018

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The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins

21 January 2018

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Myelin-associated mRNA and protein expression deficits in the anterior cingulate cortex and hippocampus in elderly schizophrenia patients.

21 January 2018

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The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation

21 January 2018

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Remyelinating strategies for the treatment of multiple sclerosis

21 January 2018

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Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961.

21 January 2018

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Mechanisms of regulation of oligodendrocyte development by p38 mitogen-activated protein kinase

21 January 2018

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Identification of Sox17 as a transcription factor that regulates oligodendrocyte development.

21 January 2018

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ID2: A negative transcription factor regulating oligodendroglia differentiation

21 January 2018

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Wnt signaling controls the timing of oligodendrocyte development in the spinal cord.

21 January 2018

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Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

21 January 2018

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Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia.

21 January 2018

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DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia.

21 January 2018

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Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes.

21 January 2018

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NBN defined medium supports the development of O4+/O1- immunopanned pro-oligodendroglia

21 January 2018

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Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis

21 January 2018

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Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats

21 January 2018

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Modulating myelination: knowing when to say Wnt.

21 January 2018

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The QKI-PLP pathway controls SIRT2 abundance in CNS myelin

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Quaking I controls a unique cytoplasmic pathway that regulates alternative splicing of myelin-associated glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Quetiapine alleviates the cuprizone-induced white matter pathology in the brain of C57BL/6 mouse.

21 January 2018

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Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

21 January 2018

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Olanzapine increases cell mitotic activity and oligodendrocyte-lineage cells in the hypothalamus

21 January 2018

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Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Quetiapine attenuates the immobilization stress-induced decrease of brain-derived neurotrophic factor expression in rat hippocampus

21 January 2018

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The discoidin domain receptor 1 as a novel susceptibility gene for schizophrenia

21 January 2018

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Chronic haloperidol treatment results in a decrease in the expression of myelin/oligodendrocyte-related genes in the mouse brain

21 January 2018

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Regulation of oligodendrocyte development in the vertebrate CNS.

21 January 2018

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The role of serotonin receptors in the action of atypical antipsychotic drugs

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Demyelination in the juvenile period, but not in adulthood, leads to long-lasting cognitive impairment and deficient social interaction in mice.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Nuclear retention of MBP mRNAs in the quaking viable mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Cholesterol of myelin is the determinant of gray-white contrast in MRI of brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Finding schizophrenia genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Olanzapine stimulates proliferation but inhibits differentiation in rat oligodendrocyte precursor cell cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Expression of mutant human DISC1 in mice supports abnormalities in differentiation of oligodendrocytes

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Maintenance of long-term efficacy and safety of quetiapine in the open-label treatment of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Triiodothyronine is a survival factor for developing oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Myelin proteomics: molecular anatomy of an insulating sheath

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

The quaking I-5 protein (QKI-5) has a novel nuclear localization signal and shuttles between the nucleus and the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Expression of QKI proteins and MAP1B identifies actively myelinating oligodendrocytes in adult rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Molecular and cellular evidence for an oligodendrocyte abnormality in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Dysfunctional brain networks and genetic risk for schizophrenia: specific neurotransmitter systems

21 January 2018

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Atypical antipsychotics attenuate neurotoxicity of beta-amyloid(25-35) by modulating Bax and Bcl-X(l/s) expression and localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Quetiapine in the treatment of schizophrenia and related disorders

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

The ability of atypical antipsychotic drugs vs. haloperidol to protect PC12 cells against MPP+‐induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Diffusion tensor imaging in the early phase of schizophrenia: what have we learned?

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Haloperidol promotes proliferation but inhibits differentiation in rat oligodendrocyte progenitor cell cultures

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Specific functions for ERK/MAPK signaling during PNS development.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

The basis of anisotropic water diffusion in the nervous system - a technical review

21 January 2018

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Dysregulated brain development in adult men with schizophrenia: a magnetic resonance imaging study

21 January 2018

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21 January 2018

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Subcortical oligodendrocyte- and astrocyte-associated gene expression in subjects with schizophrenia, major depression and bipolar disorder

21 January 2018

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Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Human QKI, a new candidate gene for schizophrenia involved in myelination.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

Microarray analysis of postmortem temporal cortex from patients with schizophrenia

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Association between golli-MBP and schizophrenia in the Jewish Ashkenazi population: are regulatory regions involved?

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Expression of the APC tumor suppressor protein in oligodendroglia

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Wnt signaling is sufficient to perturb oligodendrocyte maturation

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Compromised myelin integrity during psychosis with repair during remission in drug-responding schizophrenia

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Long-term maintenance therapy with quetiapine versus haloperidol decanoate in patients with schizophrenia or schizoaffective disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Quantification of thalamocortical tracts in schizophrenia on probabilistic maps

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Protection of p27(Kip1) mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Ghrelin inhibits hydrogen peroxide-induced apoptotic cell death of oligodendrocytes via ERK and p38MAPK signaling

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Genetic and functional analyses identify DISC1 as a novel callosal agenesis candidate gene.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Developmentally regulated changes in c-Jun N-terminal kinase signalling determine the apoptotic response of oligodendrocyte lineage cells

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Linkage and associated studies of schizophrenia

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Myelination deficits in schizophrenia: evidence from diffusion tensor imaging.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Oligodendrocyte maturation is inhibited by bone morphogenetic protein

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https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

Recovery of behavioral changes and compromised white matter in C57BL/6 mice exposed to cuprizone: effects of antipsychotic drugs

1 reference

https://api.crossref.org/works/10.1017%2FS1461145712001095

7 January 2021

10.1017/S1461145712001095

Identifiers

DOI

1 reference

28 August 2017

1 reference