How is digit identity determined during limb development? (Q38066525)

28 August 2017

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title

How is digit identity determined during limb development? (English)

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28 August 2017

Takayuki Suzuki

1

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28 August 2017

publication date

12 December 2012

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Development, Growth and Differentiation

28 August 2017

published in

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28 August 2017

volume

55

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28 August 2017

issue

1

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28 August 2017

page(s)

130-138

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Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

28 August 2017

cites work

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Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis

21 January 2018

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Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.

21 January 2018

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Expression profile of Gli family members and Shh in normal and mutant mouse limb development.

21 January 2018

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Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb

21 January 2018

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Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal

21 January 2018

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Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

21 January 2018

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Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh.

21 January 2018

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Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened

21 January 2018

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Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

21 January 2018

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Interdigital regulation of digit identity and homeotic transformation by modulated BMP signaling

21 January 2018

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The chicken polydactyly (Po) locus causes allelic imbalance and ectopic expression of Shh during limb development

21 January 2018

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A series of normal stages in the development of the chick embryo

21 January 2018

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Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

21 January 2018

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A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud.

21 January 2018

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Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu.

21 January 2018

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Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors

21 January 2018

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Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function.

21 January 2018

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Beta-arrestin-mediated localization of smoothened to the primary cilium

21 January 2018

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Cholesterol modification restricts the spread of Shh gradient in the limb bud.

21 January 2018

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Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

21 January 2018

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Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

21 January 2018

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Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage.

21 January 2018

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GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis

21 January 2018

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Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations

21 January 2018

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BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling.

21 January 2018

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Identification of a palmitic acid-modified form of human Sonic hedgehog

21 January 2018

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Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

21 January 2018

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Sonic hedgehog mediates the polarizing activity of the ZPA

21 January 2018

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The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limb

21 January 2018

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Developmental control of three-dimensional polarity in the avian limb

21 January 2018

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Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb

21 January 2018

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Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes

21 January 2018

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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

21 January 2018

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Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity

21 January 2018

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Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling.

21 January 2018

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Embryological evidence identifies wing digits in birds as digits 1, 2, and 3.

21 January 2018

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Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

21 January 2018

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Integration of growth and specification in chick wing digit-patterning.

21 January 2018

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Insights into bird wing evolution and digit specification from polarizing region fate maps

21 January 2018

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Birds have dinosaur wings: The molecular evidence

21 January 2018

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The digits of the wing of birds are 1, 2, and 3. A review

21 January 2018

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Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning.

21 January 2018

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21 January 2018

On the nature of thumbs.

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Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

21 January 2018

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Transcriptomic analysis of avian digits reveals conserved and derived digit identities in birds.

21 January 2018

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Positional information and the spatial pattern of cellular differentiation

21 January 2018

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The origin of digits: expression patterns versus regulatory mechanisms.

21 January 2018

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Identity of the avian wing digits: problems resolved and unsolved.

21 January 2018

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Why ontogenetic homology criteria can be misleading: lessons from digit identity transformations

21 January 2018

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Uncoupling Sonic Hedgehog Control of Pattern and Expansion of the Developing Limb Bud

21 January 2018

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A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways.

21 January 2018

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Positional signalling and specification of digits in chick limb morphogenesis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/DGD.12022

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28 August 2017

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