Mechanisms of T cell tolerance towards the allogeneic fetus (Q38067209)

28 August 2017

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title

Mechanisms of T cell tolerance towards the allogeneic fetus (English)

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28 August 2017

Adrian Erlebacher

1

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28 August 2017

14 December 2012

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Nature Reviews Immunology

28 August 2017

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28 August 2017

13

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28 August 2017

1

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28 August 2017

23-33

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https://scigraph.springernature.com/pub.10.1038/nri3361

28 August 2017

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Pregnancy imprints regulatory memory that sustains anergy to fetal antigen

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Regulatory T cells mediate maternal tolerance to the fetus

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Regulatory T cells induce a privileged tolerant microenvironment at the fetal-maternal interface

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FOXP3+ regulatory T cells and T helper 1, T helper 2, and T helper 17 cells in human early pregnancy decidua

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Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogens

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Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific

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Maternal PD-1 regulates accumulation of fetal antigen-specific CD8+ T cells in pregnancy

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The Th2 cytokines IL-4 and IL-10 are not crucial for the completion of allogeneic pregnancy in mice.

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Uterine NK cells mediate inflammation-induced fetal demise in IL-10-null mice

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31 March 2020

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Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin.

31 March 2020

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31 March 2020

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31 March 2020

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Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface

31 March 2020

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31 March 2020

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Quantitative analysis of T lymphocyte subsets in pregnant and nonpregnant human endometrium

31 March 2020

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The frequency, clinical significance, and pathological features of chronic chorioamnionitis: a lesion associated with spontaneous preterm birth.

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Localization of fetal major histocompatibility complex antigens and maternal leukocytes in murine placenta. Implications for maternal-fetal immunological relationship

31 March 2020

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12 December 2020

Contributions of direct and indirect T cell alloreactivity during allograft rejection in mice.

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12 December 2020

Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in mice

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12 December 2020

Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation

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12 December 2020

Identifiers

DOI

10.1038/NRI3361

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PubMed ID

23237963

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23237963