Current options for drug delivery to the spinal cord (Q38071680)

28 August 2017

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title

Current options for drug delivery to the spinal cord (English)

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28 August 2017

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Filippo Rossi

1

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28 August 2017

Giuseppe Perale

2

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28 August 2017

Simonetta Papa

3

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28 August 2017

Gianluigi Forloni

4

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28 August 2017

Pietro Veglianese

5

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28 August 2017

language of work or name

English

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publication date

6 January 2013

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Expert Opinion on Drug Delivery

28 August 2017

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28 August 2017

10

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28 August 2017

3

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28 August 2017

385-396

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Current and prospective disease-modifying therapies for amyotrophic lateral sclerosis

28 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Pharmacological interventions for spinal cord injury: where do we stand? How might we step forward?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

New considerations in the design of clinical trials for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

The blood-spinal cord barrier: morphology and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Looking at the blood-brain barrier: molecular anatomy and possible investigation approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Comparison of the effectiveness of amitriptyline and gabapentin on chronic neuropathic pain in persons with spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Morphine-6-glucuronide: actions and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Long-term outcomes during treatment of chronic pain with intrathecal clonidine or clonidine/opioid combinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Molecular pharmacology of the opioid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Spasticity: pathophysiology, evaluation and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Intrathecal baclofen therapy for neurological disorders: a sound knowledge base but many challenges remain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Considerations in the treatment of spasticity with intrathecal baclofen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Enhanced disruption of the blood brain barrier by intracarotid mannitol injection during transient cerebral hypoperfusion in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Intracarotid administration of short-chain alkylglycerols for increased delivery of methotrexate to the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: from concept to clinical evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Ultrasound for drug and gene delivery to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Drug and gene delivery to the brain: the vascular route

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Brain drug targeting and gene technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

A lymphotropic prodrug of L-dopa: synthesis, pharmacological properties, and pharmacokinetic behavior of 1,3-dihexadecanoyl-2-[(S)-2-amino-3-(3,4-dihydroxyphenyl)prop anoyl] propane-1,2,3-triol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Targeting drugs to the brain by redox chemical delivery systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Delivery of peptides and proteins through the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Delivery of galanin-like peptide to the brain: targeting with intranasal delivery and cyclodextrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Blood-brain barrier drug targeting: the future of brain drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Delivery of beta-galactosidase to mouse brain via the blood-brain barrier transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Novel multifunctional polyethylene glycol-transactivating-transduction protein-modified liposomes cross the blood-spinal cord barrier after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

PEGlated magnetic polymeric liposome anchored with TAT for delivery of drugs across the blood-spinal cord barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Repairing the damaged spinal cord and brain with nanomedicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Microparticles and nanoparticles for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Drug delivery applications for superporous hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Surface functionalization of nanoparticles for nanomedicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Nanoparticle-mediated cellular response is size-dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Polymer particles that switch shape in response to a stimulus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Sustained intraspinal delivery of neurotrophic factor encapsulated in biodegradable nanoparticles following contusive spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Differential uptake of functionalized polystyrene nanoparticles by human macrophages and a monocytic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Functional silica nanoparticle-mediated neuronal membrane sealing following traumatic spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Nanoparticle-mediated local delivery of Methylprednisolone after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Nano PGE1 promoted the recovery from spinal cord injury-induced motor dysfunction through its accumulation and sustained release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Cerebrolysin, a mixture of neurotrophic factors induces marked neuroprotection in spinal cord injury following intoxication of engineered nanoparticles from metals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Intrathecal delivery of a polymeric nanocomposite hydrogel after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Incorporation of protein-eluting microspheres into biodegradable nerve guidance channels for controlled release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Nerve guidance channels as drug delivery vehicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Use of implantable pumps for central nervous system drug infusions to treat neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Mechanisms of action of intrathecal medications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Advances in intrathecal drug delivery

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Drug delivery to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Intrathecal baclofen in multiple sclerosis: too little, too late?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Intrathecal drug therapy for long-term pain management

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

21 January 2018

Intrathecal analgesia.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

An injectable drug delivery platform for sustained combination therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Hydrogels in regenerative medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Hydrogels in spinal cord injury repair strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Effect of modulating macrophage phenotype on peripheral nerve repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Semi-interpenetrating network of polyethylene glycol and photocrosslinkable chitosan as an in-situ-forming nerve adhesive

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

In situ gelling hydrogels for conformal repair of spinal cord defects, and local delivery of BDNF after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Controlled release of 6-aminonicotinamide from aligned, electrospun fibers alters astrocyte metabolism and dorsal root ganglia neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Biocompatibility of amphiphilic diblock copolypeptide hydrogels in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Accelerated release of a sparingly soluble drug from an injectable hyaluronan-methylcellulose hydrogel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

A new paradigm for local and sustained release of therapeutic molecules to the injured spinal cord for neuroprotection and tissue repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

In situ cross-linkable high molecular weight hyaluronan-bisphosphonate conjugate for localized delivery and cell-specific targeting: a hydrogel linked prodrug approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

The use of superporous Ac-CGGASIKVAVS-OH-modified PHEMA scaffolds to promote cell adhesion and the differentiation of human fetal neural precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Tunable growth factor delivery from injectable hydrogels for tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Why degradable polymers undergo surface erosion or bulk erosion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Nanowired drug delivery of antioxidant compound H-290/51 enhances neuroprotection in hyperthermia-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Early microvascular reactions and blood-spinal cord barrier disruption are instrumental in pathophysiology of spinal cord injury and repair: novel therapeutic strategies including nanowired drug delivery to enhance neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Drug delivery to the spinal cord tagged with nanowire enhances neuroprotective efficacy and functional recovery following trauma to the rat spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Nanowired drug delivery to enhance neuroprotection in spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

A systematic review of directly applied biologic therapies for acute spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

A systematic review of cellular transplantation therapies for spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Controlled release of chondroitinase ABC from fibrin gel reduces the level of inhibitory glycosaminoglycan chains in lesioned spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Sustained Delivery of Chondroitinase ABC from Hydrogel System

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Sustained release of neurotrophin-3 and chondroitinase ABC from electrospun collagen nanofiber scaffold for spinal cord injury repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Linear ordered collagen scaffolds loaded with collagen-binding brain-derived neurotrophic factor improve the recovery of spinal cord injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

The promotion of neurological recovery in the rat spinal cord crushed injury model by collagen-binding BDNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Time Controlled Protein Release from Layer-by-Layer Assembled Multilayer Functionalized Agarose Hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Injectable intrathecal delivery system for localized administration of EGF and FGF-2 to the injured rat spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Multifunctionalized CMCht/PAMAM Dendrimer Nanoparticles Modulate the Cellular Uptake by Astrocytes and Oligodendrocytes in Primary Cultures of Glial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Drug transport across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

Multiple drug delivery hydrogel system for spinal cord injury repair strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

In vitro sustained release of bioactive anti-NogoA, a molecule in clinical development for treatment of spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2013.751372

10.1517/17425247.2013.751372

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference