Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications (Q38071700)

28 August 2017

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title

Effect of the ATP-binding cassette transporter ABCG2 on pharmacokinetics: experimental findings and clinical implications (English)

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28 August 2017

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Rebecca Schnepf

1

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28 August 2017

Oliver Zolk

series ordinal

2

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28 August 2017

language of work or name

English

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publication date

7 January 2013

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Expert Opinion on Drug Metabolism & Toxicology

28 August 2017

published in

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28 August 2017

volume

9

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28 August 2017

issue

3

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28 August 2017

page(s)

287-306

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Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk

28 August 2017

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Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

21 January 2018

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ABCG2 null alleles define the Jr(a-) blood group phenotype

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Null alleles of ABCG2 encoding the breast cancer resistance protein define the new blood group system Junior

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A multidrug resistance transporter from human MCF-7 breast cancer cells

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In Vitro and In Vivo Evidence for the Importance of Breast Cancer Resistance Protein Transporters (BCRP/MXR/ABCP/ABCG2)

21 January 2018

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Breast cancer resistance protein (BCRP) affected acquired resistance to gefitinib in a "never-smoked" female patient with advanced non-small cell lung cancer.

21 January 2018

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ABCG2: the key to chemoresistance in cancer stem cells?

21 January 2018

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Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model

21 January 2018

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Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice

21 January 2018

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Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2013.742063

ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2013.742063

QSAR analysis and molecular modeling of ABCG2-specific inhibitors

21 January 2018

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Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2013.742063

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Drug transporters and imatinib treatment: implications for clinical practice

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Involvement of breast cancer resistance protein (BCRP1/ABCG2) in the bioavailability and tissue distribution of trans-resveratrol in knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Role of the ABCG2 drug transporter in the resistance and oral bioavailability of a potent cyclin-dependent kinase/Aurora kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Deletion of Abcg2 has differential effects on excretion and pharmacokinetics of probe substrates in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

ABCB1 and ABCG2 expression in the placenta and fetus: an interspecies comparison

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Drug points: Severe myalgia from an interaction between treatments with pantoprazole and methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benzbromarone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Interactions of cyclosporin a with breast cancer resistance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Modulation of human BCRP (ABCG2) activity by anti-HIV drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Drug/Drug interaction between lopinavir/ritonavir and rosuvastatin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Single nucleotide polymorphisms modify the transporter activity of ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Functional analysis of SNPs variants of BCRP/ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in the clinical trials for novel drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Effect of ABCG2 genotype on the oral bioavailability of topotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Pharmacogenomic importance of ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Transporter pharmacogenetics and statin toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Development of sulfasalazine resistance in human T cells induces expression of the multidrug resistance transporter ABCG2 (BCRP) and augmented production of TNFalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Oral sulfasalazine as a clinical BCRP probe substrate: pharmacokinetic effects of genetic variation (C421A) and pantoprazole coadministration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Progesterone receptor downregulates breast cancer resistance protein expression via binding to the progesterone response element in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Transcriptional upregulation of breast cancer resistance protein by 17beta-estradiol in ERalpha-positive MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

ABCG2/BCRP dysfunction as a major cause of gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

ABC transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) expression in the developing human CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Vascular colocalization of P-glycoprotein, multidrug-resistance associated protein 1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Localisation of breast cancer resistance protein in microvessel endothelium of human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood–brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Double-transduced MDCKII cells to study human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) interplay in drug transport across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

P-glycoprotein and breast cancer resistance protein: two dominant transporters working together in limiting the brain penetration of topotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict brain accumulation of the active sunitinib metabolite N-desethyl sunitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Quantitative proteomics of transporter expression in brain capillary endothelial cells isolated from P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and P-gp/Bcrp knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The role of efflux and uptake transporters in [N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, lapatinib) disposition and drug interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Brain accumulation of dasatinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by elacridar treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Distribution of gefitinib to the brain is limited by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)-mediated active efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-type mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Induction of cellular resistance to nucleoside reverse transcriptase inhibitors by the wild-type breast cancer resistance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Abcg2/Bcrp1 mediates the polarized transport of antiretroviral nucleosides abacavir and zidovudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) on pharmacokinetics and central nervous system penetration of abacavir and zidovudine in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Lack of interactions between breast cancer resistance protein (bcrp/abcg2) and selected antiepileptic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Multidrug resistance proteins (MRPs, ABCCs): importance for pathophysiology and drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Efflux transporters in the blood-brain interfaces--in vitro and in vivo methods and correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Membrane transporters in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The effect of ABCG2 V12M, Q141K and Q126X, known functional variants in vitro, on the disposition of lamivudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Effect of ABCG2 genotypes on the pharmacokinetics of A771726, an active metabolite of prodrug leflunomide, and association of A771726 exposure with serum uric acid level

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Pharmacogenetic determinants of statin-induced reductions in C-reactive protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

A gene atlas of the mouse and human protein-encoding transcriptomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Tissue-specific mRNA expression profiles of human ATP-binding cassette and solute carrier transporter superfamilies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Effect of breast cancer resistance protein (Bcrp/Abcg2) on the disposition of phytoestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Brain penetration of ivermectin and selamectin in mdr1a,b P-glycoprotein- and bcrp- deficient knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

The Role of the Breast Cancer Resistance Protein (ABCG2) in the Distribution of Sorafenib to the Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Bioavailability of the Glucuronide and Sulfate Conjugates of Genistein and Daidzein in Breast Cancer Resistance Protein 1 Knockout Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2013.742063

10.1517/17425255.2013.742063

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference