The disconnect between phase II and phase III trials of drugs for heart failure (Q38072257)

28 August 2017

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title

The disconnect between phase II and phase III trials of drugs for heart failure (English)

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28 August 2017

phase III clinical trial

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phase II clinical trial

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4

Mihai Gheorghiade

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28 August 2017

5

Javed Butler

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28 August 2017

Muthiah Vaduganathan

1

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28 August 2017

Stephen J Greene

series ordinal

2

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28 August 2017

Andrew P Ambrosy

series ordinal

3

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28 August 2017

language of work or name

English

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publication date

8 January 2013

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Nature Reviews Cardiology

28 August 2017

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28 August 2017

10

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28 August 2017

2

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28 August 2017

85-97

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https://scigraph.springernature.com/pub.10.1038/nrcardio.2012.181

28 August 2017

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cites work

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Levosimendan vs dobutamine for patients with acute decompensated heart failure: the SURVIVE Randomized Trial

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31 March 2020

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31 March 2020

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Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD)

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Effect of nesiritide in patients with acute decompensated heart failure

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

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31 March 2020

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Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study

31 March 2020

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Improving postdischarge outcomes in patients hospitalized for acute heart failure syndromes

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Beyond dyspnoea as an endpoint in acute heart failure trials

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

The impact of early standard therapy on dyspnoea in patients with acute heart failure: the URGENT-dyspnoea study

31 March 2020

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31 March 2020

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Effects of tolvaptan on dyspnoea relief from the EVEREST trials

31 March 2020

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Weight changes after hospitalization for worsening heart failure and subsequent re-hospitalization and mortality in the EVEREST trial.

31 March 2020

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Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Multicenter, randomized, double-blind, placebo-controlled study on the effect of oral tolvaptan on left ventricular dilation and function in patients with heart failure and systolic dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Changes in renal function during hospitalization and soon after discharge in patients admitted for worsening heart failure in the placebo group of the EVEREST trial

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Acute heart failure syndromes

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE).

31 March 2020

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The EuroHeart Failure survey programme-- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Review of current and investigational pharmacologic agents for acute heart failure syndromes

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Bayesian adaptive trial design in acute heart failure syndromes: moving beyond the mega trial

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRCARDIO.2012.181

Heart disease and stroke statistics--2012 update: a report from the American Heart Association

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23296069

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23296069

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRCARDIO.2012.181

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Dimensions Publication ID

28 August 2017

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1 reference