Oxidative stress and immunosenescence: therapeutic effects of melatonin (Q38076420)

28 August 2017

6 references

2 October 2019

12 October 2019

18 October 2019

17 November 2019

11 October 2020

25 January 2021

Oxidative stress and immunosenescence: therapeutic effects of melatonin (English)

1 reference

28 August 2017

1 reference

25 January 2021

1 reference

2 October 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

17 November 2019

1 reference

11 October 2020

Javier Espino

1

0 references

author name string

José A Pariente

series ordinal

2

1 reference

PMC publication ID

3549369

28 August 2017

Ana B Rodríguez

series ordinal

3

1 reference

28 August 2017

31 December 2012

7 references

Oxidative Medicine and Cellular Longevity

28 August 2017

2 October 2019

12 October 2019

18 October 2019

17 November 2019

11 October 2020

25 January 2021

7 references

28 August 2017

2 October 2019

12 October 2019

18 October 2019

17 November 2019

11 October 2020

25 January 2021

2012

1 reference

28 August 2017

670294

1 reference

Creative Commons Attribution 3.0 Unported

28 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Melatonin mitigates mitochondrial malfunction

6 September 2017

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Is immunosenescence infectious?

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6 September 2017

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Enzymatic O-methylation of N-acetylserotonin to melatonin

6 September 2017

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6 September 2017

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Melatonin and immune function: hype or hypothesis?

6 September 2017

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Melatonin reduces oxidant damage and promotes mitochondrial respiration: implications for aging

6 September 2017

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6 September 2017

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Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice

6 September 2017

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6 September 2017

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The unexpected contribution of immunosenescence to the leveling off of cancer incidence and mortality in the oldest old.

6 September 2017

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Melatonin and its relation to the immune system and inflammation

6 September 2017

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Alterations of antioxidant enzymes and oxidative stress markers in aging

6 September 2017

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Actions of melatonin in the reduction of oxidative stress. A review

6 September 2017

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6 September 2017

On the nature of aging

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Inflamm-aging. An evolutionary perspective on immunosenescence

6 September 2017

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Melatonin and cardiovascular function

6 September 2017

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Biomarkers of immunosenescence within an evolutionary perspective: the challenge of heterogeneity and the role of antigenic load

6 September 2017

1 reference

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The immune system in the elderly: III. Innate immunity

6 September 2017

1 reference

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Melatonin regulates glucocorticoid receptor: an answer to its antiapoptotic action in thymus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

The biologic clock: the mitochondria?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Melatonin: the chemical expression of darkness

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

6 September 2017

1 reference

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The ageing pineal gland and its physiological consequences

6 September 2017

1 reference

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Damaging effects of advanced glycation end-products in the murine macrophage cell line J774A.1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Melatonin counteracts alterations in oxidative metabolism and cell viability induced by intracellular calcium overload in human leucocytes: changes with age.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Low-grade inflammation with aging has consequences for T-lymphocyte signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Suppression of both basal and antigen-induced lipid peroxidation in ring dove heterophils by melatonin

23 June 2018

1 reference

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From naive to effector--alterations with aging

23 June 2018

1 reference

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Efficacy of melatonin as a sleep-promoting agent

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Efficacy of melatonin treatment in jet lag, shift work, and blindness.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Circadian entrainment and phase shifting in mammals with melatonin

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Role of the pineal gland in immunity. Circadian synthesis and release of melatonin modulates the antibody response and antagonizes the immunosuppressive effect of corticosterone

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Aging and vascular dysfunction: beneficial melatonin effects.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Melatonin improves D-galactose-induced aging effects on behavior, neurogenesis, and lipid peroxidation in the mouse dentate gyrus via increasing pCREB expression

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Advanced glycation end products induce T cell apoptosis: Involvement of oxidative stress, caspase and the mitochondrial pathway

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation

31 August 2018

1 reference

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Immunosenescence of polymorphonuclear neutrophils.

31 August 2018

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Age-induced reduction in mitochondrial manganese superoxide dismutase activity and tolerance of macrophages against apoptosis induced by oxidized low density lipoprotein

31 August 2018

1 reference

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Lower expression of catalytic and structural subunits of the proteasome contributes to decreased proteolysis in peripheral blood T lymphocytes during aging.

31 August 2018

1 reference

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Does melatonin improve sleep? Efficacy of melatonin

31 August 2018

1 reference

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Melatonin attenuates diabetes-induced oxidative stress in rabbits

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Melatonin, lipid peroxidation, and age in heterophils from the ring dove (Streptopelia risoria).

31 August 2018

1 reference

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Changes with age in peritoneal macrophage functions. Implication of leukocytes in the oxidative stress of senescence.

31 August 2018

1 reference

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Neutrophils as a specific target for melatonin and kynuramines: effects on cytokine release

31 August 2018

1 reference

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Melatonin rejuvenates degenerated thymus and redresses peripheral immune functions in aged mice

31 August 2018

1 reference

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Oxidative inactivation of CD45 protein tyrosine phosphatase may contribute to T lymphocyte dysfunction in the elderly

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Melatonin: an antioxidant at physiological concentrations

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Pineal indoles stimulate the gene expression of immunomodulating cytokines

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Antioxidant enzyme activities and malondialdehyde levels related to aging

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Superoxide dismutase, catalase and glutathione peroxidase activities in human blood: influence of sex, age and cigarette smoking.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Different IL-8 production by T and NK lymphocytes in elderly subjects

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Circadian organization of the immune response: A role for melatonin

1 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F670294

Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F670294

Jerte Valley cherry-based product modulates serum inflammatory markers in rats and ringdoves

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2012%2F670294

Accessory Function and Properties of Monocytes from Healthy Elderly Humans for T Lymphocyte Responses to Mitogen and Antigen

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549369

Identification of highly elevated levels of melatonin in bone marrow: its origin and significance

3 December 2018

1 reference

12 December 2020

Effect of melatonin on the oxidative stress in erythrocytes of healthy young and elderly subjects

1 reference

12 December 2020

Immunosenescence: impact in the young as well as the old?

1 reference

12 December 2020

Augmentation of indices of oxidative damage in life-long melatonin-deficient rats

1 reference

12 December 2020

Differential expression of the melatonin receptor in human monocytes

1 reference

12 December 2020

Hematopoietic rescue via T-cell-dependent, endogenous granulocyte-macrophage colony-stimulating factor induced by the pineal neurohormone melatonin in tumor-bearing mice

1 reference

12 December 2020

Involvement of nuclear binding sites for melatonin in the regulation of IL-2 and IL-6 production by human blood mononuclear cells

1 reference

12 December 2020

The pineal neurohormone melatonin prevents in vivo and in vitro apoptosis in thymocytes

1 reference

12 December 2020

Exogenous melatonin: quantitative enhancement in vivo of cells mediating non-specific immunity

1 reference

12 December 2020

Colony-stimulating activity and hematopoietic rescue from cancer chemotherapy compounds are induced by melatonin via endogenous interleukin 4

1 reference

12 December 2020

Activation of human monocytes by the pineal hormone melatonin

1 reference

12 December 2020

Melatonin inhibits apoptosis during early B-cell development in mouse bone marrow

1 reference

12 December 2020

Role of phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways in granulocyte macrophage-colony-stimulating factor failure to delay fas-induced neutrophil apoptosis in elderly humans

1 reference

12 December 2020

Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum

1 reference

12 December 2020

Melatonin enhances IL-2, IL-6, and IFN-gamma production by human circulating CD4+ cells: a possible nuclear receptor-mediated mechanism involving T helper type 1 lymphocytes and monocytes

1 reference

12 December 2020

Functional alteration of granulocytes, NK cells, and natural killer T cells in centenarians

1 reference

12 December 2020

Physiological levels of melatonin contribute to the antioxidant capacity of human serum

1 reference

12 December 2020

Spontaneous and Fas-induced apoptotic cell death in aged neutrophils

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/670294

1 reference

28 August 2017

1 reference

PMC publication ID

3549369

28 August 2017

PubMed publication ID

23346283

1 reference

PMC publication ID

3549369