Targeting RANKL in breast cancer: bone metastasis and beyond (Q38081245)

28 August 2017

Targeting RANKL in breast cancer: bone metastasis and beyond (English)

1 reference

28 August 2017

1 reference

Hamdy Azim

1

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PubMed ID

23406560

28 August 2017

Hatem A Azim

series ordinal

2

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28 August 2017

1 February 2013

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Expert Review of Anticancer Therapy

28 August 2017

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28 August 2017

13

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28 August 2017

2

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28 August 2017

195-201

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The clinical course of bone metastases from breast cancer

28 August 2017

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Bone metastasis: histological changes and pathophysiological mechanisms in osteolytic or osteosclerotic localizations. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

RANKL signaling in bone physiology and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

The cell biology of bone metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Cell biology of the osteoclast

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Molecular pathways: osteoclast-dependent and osteoclast-independent roles of the RANKL/RANK/OPG pathway in tumorigenesis and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Osteoclast differentiation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Expression pattern of receptor activator of NFκB (RANK) in a series of primary solid tumors and related bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Bone metastasis in breast cancer: the story of RANK-ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Bone metastasis: mechanisms and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Metastasis to bone: causes, consequences and therapeutic opportunities

21 January 2018

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https://api.crossref.org/works/10.1586%2FERA.12.177

TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

The calcium sensing receptor: from understanding parathyroid calcium homeostasis to bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Expression of the calcium receptor in human breast cancer--a potential new marker predicting the risk of bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Small is beautiful: insulin-like growth factors and their role in growth, development, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

The role of the IGF system in cancer growth and metastasis: overview and recent insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Inhibition of bone resorption and growth of breast cancer in the bone microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Regulation of cancer cell migration and bone metastasis by RANKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

21 January 2018

Physiology of bone loss

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https://api.crossref.org/works/10.1586%2FERA.12.177

Estrogen regulation of immune cell bone interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Estrogen prevents bone loss through transforming growth factor beta signaling in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Role of RANK ligand in mediating increased bone resorption in early postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

New regulation mechanisms of osteoclast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Novel functions of RANK(L) signaling in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Denosumab for prevention of fractures in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Effect of denosumab on bone mineral density in women receiving adjuvant aromatase inhibitors for non-metastatic breast cancer: subgroup analyses of a phase 3 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

RANK overexpression in transgenic mice with mouse mammary tumor virus promoter-controlled RANK increases proliferation and impairs alveolar differentiation in the mammary epithelia and disrupts lumen formation in cultured epithelial acini

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Breast tenderness after initiation of conjugated equine estrogens and mammographic density change

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Does hormone replacement therapy cause breast cancer? An application of causal principles to three studies. Part 4: the Million Women Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Progesterone induces adult mammary stem cell expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Steroid receptors and cell cycle in normal mammary epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Steroid hormone receptor status of mouse mammary stem cells

21 January 2018

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https://api.crossref.org/works/10.1586%2FERA.12.177

Control of mammary stem cell function by steroid hormone signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Accumulation of regulatory T cells in sentinel lymph nodes is a prognostic predictor in patients with node-negative breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Comparison of the prognostic and predictive utilities of the 21-gene Recurrence Score assay and Adjuvant! for women with node-negative, ER-positive breast cancer: results from NSABP B-14 and NSABP B-20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Elucidating prognosis and biology of breast cancer arising in young women using gene expression profiling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Prognosis and adjuvant treatment effects in selected breast cancer subtypes of very young women (<35 years) with operable breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Effects of young age at presentation on survival in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

Breast cancer in young women: poor survival despite intensive treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERA.12.177

21 January 2018

Identifiers

DOI

10.1586/ERA.12.177

1 reference

28 August 2017

1 reference

PubMed ID

23406560