Current advanced bioluminescence technology in drug discovery (Q38088810)

28 August 2017

title

Current advanced bioluminescence technology in drug discovery (English)

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28 August 2017

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Hideto Hoshino

1

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28 August 2017

language of work or name

English

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publication date

1 April 2009

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Expert Opinion on Drug Discovery

28 August 2017

published in

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28 August 2017

volume

4

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28 August 2017

issue

4

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28 August 2017

page(s)

373-389

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Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli

28 August 2017

cites work

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Firefly luciferase luminescence assays using scintillation counters for quantitation in transfected mammalian cells

21 January 2018

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Reporter gene technology: the future looks bright

21 January 2018

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Complementary DNA coding click beetle luciferases can elicit bioluminescence of different colors

21 January 2018

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Cloning, sequence analysis, and expression of active Phrixothrix railroad-worms luciferases: relationship between bioluminescence spectra and primary structures.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Isolation and expression of a cDNA encoding Renilla reniformis luciferase

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

cDNA cloning and characterization of a secreted luciferase from the luminous Japanese ostracod, Cypridina noctiluca.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Cloning and expression of cDNA for the luciferase from the marine ostracod Vargula hilgendorfii

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Cloning and sequence analysis of cDNA for luciferase of a Japanese firefly, Luciola cruciata

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Cloning and functional expression of a novel long-chain acyl-CoA synthetase expressed in brain

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Cloning, expression and sequence analysis of cDNA for the luciferases from the Japanese fireflies, Pyrocoelia miyako and Hotaria parvula

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Molecular cloning and expression of the cDNAs encoding luciferin-regenerating enzyme from Luciola cruciata and Luciola lateralis

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Molecular cloning and expression of a cDNA encoding the luciferase from the firefly, Hotaria unmunsana

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Molecular cloning and expression of a cDNA encoding the luciferase from the firefly, Pyrocoelia rufa

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Luciferase from the Italian firefly Luciola italica: molecular cloning and expression

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

cDNA cloning, expression and homology modeling of a luciferase from the firefly Lampyroidea maculata

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Molecular cloning, sequence analysis, and expression of a cDNA encoding the luciferase from the glow-worm, Lampyris turkestanicus.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Darwinian natural selection for orange bioluminescent color in a Jamaican click beetle

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Cloning and expression of cDNA for a luciferase from the marine copepod Metridia longa. A novel secreted bioluminescent reporter enzyme

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Thr226 is a key residue for bioluminescence spectra determination in beetle luciferases

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Spectral emission and quantum yield of firefly bioluminescence

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Bioluminescence of the firefly: key steps in the formation of the electronically excited state for model systems

21 January 2018

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Enhanced microbial biomass assay using mutant luciferase resistant to benzalkonium chloride

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Transcriptional regulation of the mouse presenilin-1 gene

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Bidirectional role of orphan nuclear receptor RORalpha in clock gene transcriptions demonstrated by a novel reporter assay system.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Multicolor luciferase assay system: one-step monitoring of multiple gene expressions with a single substrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: temperature compensation and damping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

CIPC is a mammalian circadian clock protein without invertebrate homologues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Simultaneous monitoring of independent gene expression patterns in two types of cocultured fibroblasts with different color-emitting luciferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Recombinant Gaussia luciferase. Overexpression, purification, and analytical application of a bioluminescent reporter for DNA hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

A highly sensitive assay for monitoring the secretory pathway and ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Real-time bioluminescence imaging of a protein secretory pathway in living mammalian cells using Gaussia luciferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Quantitation of autophagy by luciferase release assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Mutant torsinA interferes with protein processing through the secretory pathway in DYT1 dystonia cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F17460440902804372

Perfusion-culture-based secreted bioluminescence reporter assay in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Dual-reporter assay using two secreted luciferase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

New reporter system for Per1 and Bmal1 expressions revealed self-sustained circadian rhythms in peripheral tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Combining intracellular and secreted bioluminescent reporter proteins for multicolor cell-based assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Resonance energy transfer: methods and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Direct comparison of fluorescence- and bioluminescence-based resonance energy transfer methods for real-time monitoring of thrombin-catalysed proteolytic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Crystal Structures of the Luciferase and Green Fluorescent Protein from Renilla reniformis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Luciferase-YFP fusion tag with enhanced emission for single-cell luminescence imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Red-shifted Renilla reniformis luciferase variants for imaging in living subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Imaging protein interactions with bioluminescence resonance energy transfer (BRET) in plant and mammalian cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein-protein interactions in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein-coupled receptors in live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Bioluminescent indicator for determining protein-protein interactions using intramolecular complementation of split click beetle luciferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Monitoring Protein−Protein Interactions Using Split Synthetic Renilla Luciferase Protein-Fragment-Assisted Complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Combining protein complementation assays with resonance energy transfer to detect multipartner protein complexes in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Dimerization in the absence of higher-order oligomerization of the G protein-coupled secretin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Detection of higher-order G protein-coupled receptor oligomers by a combined BRET-BiFC technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Detection of heteromerization of more than two proteins by sequential BRET-FRET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Constitutive and agonist-dependent homo-oligomerization of the thyrotropin-releasing hormone receptor. Detection in living cells using bioluminescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Real-time monitoring of receptor and G-protein interactions in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Monitoring interactions between G-protein-coupled receptors and beta-arrestins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Real-time monitoring of ubiquitination in living cells by BRET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Development of a bioluminescence resonance energy-transfer assay for estrogen-like compound in vivo monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Molecular imaging of drug-modulated protein-protein interactions in living subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

An intramolecular folding sensor for imaging estrogen receptor-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

High-throughput sensing and noninvasive imaging of protein nuclear transport by using reconstitution of split Renilla luciferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

A genetically encoded indicator for assaying bioactive chemicals that induce nuclear transport of glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Quantitative determination of protein nuclear transport induced by phosphorylation or by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Genetically encoded optical probe for detecting release of proteins from mitochondria toward cytosol in living cells and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Firefly bioluminescence quantum yield and colour change by pH-sensitive green emission

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Bringing bioluminescence into the picture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Improved expression of novel red- and green-emitting luciferases of Phrixothrix railroad worms in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Improved QD-BRET conjugates for detection and imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Creating self-illuminating quantum dot conjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Self-illuminating quantum dot conjugates for in vivo imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

Crystalline Cypridina Luciferin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460440902804372

10.1517/17460440902804372

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

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