The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations (Q38097351)

28 August 2017

The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations (English)

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28 August 2017

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Gudmundur Johannsson

4

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Edward O List

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3

object named as

Edward O List

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28 August 2017

Darlene E Berryman

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PubMed ID

23568441

28 August 2017

Camilla A M Glad

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2

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28 August 2017

9 April 2013

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Nature Reviews Endocrinology

28 August 2017

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28 August 2017

9

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28 August 2017

346-356

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https://scigraph.springernature.com/pub.10.1038/nrendo.2013.64

28 August 2017

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21 January 2018

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Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency

21 January 2018

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The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice

21 January 2018

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The decline in pulsatile GH secretion throughout early adulthood in mice is exacerbated by dietary-induced weight gain.

21 January 2018

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Growth hormone improves body composition, fasting blood glucose, glucose tolerance and liver triacylglycerol in a mouse model of diet-induced obesity and type 2 diabetes.

21 January 2018

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Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

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GH-dependent STAT5 signaling plays an important role in hepatic lipid metabolism

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21 January 2018

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21 January 2018

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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

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Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy

21 January 2018

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Calorigenic effect of human growth hormone in obesity

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31 March 2020

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31 March 2020

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31 March 2020

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Anabolic effects of growth hormone in obese diet-restricted subjects are dose dependent

31 March 2020

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Metabolic effects of biosynthetic growth hormone treatment in severely energy-restricted obese women

31 March 2020

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Fuel metabolism, energy expenditure, and thyroid function in growth hormone-treated obese women: a double-blind placebo-controlled study

31 March 2020

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Effects of growth hormone treatment on the leptin system and on energy expenditure in abdominally obese men

31 March 2020

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Effects of growth hormone therapy on thyroid function of growth hormone-deficient adults with and without concomitant thyroxine-substituted central hypothyroidism

31 March 2020

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31 March 2020

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31 March 2020

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Growth Hormone Reduces Inflammation in Postmenopausal Women with Abdominal Obesity: A 12-Month, Randomized, Placebo-Controlled Trial

31 March 2020

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Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess

31 March 2020

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Low-dose growth hormone treatment combined with diet restriction decreases insulin resistance by reducing visceral fat and increasing muscle mass in obese type 2 diabetic patients

31 March 2020

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Persistent lipolytic effect of exogenous growth hormone during caloric restriction

31 March 2020

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Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults

31 March 2020

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Expression of Insulin-Like Growth Factor I in Transgenic Mice with Elevated Levels of Growth Hormone Is Correlated with Growth*

31 March 2020

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Effect of growth hormone on susceptibility to diet-induced obesity

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12 December 2020

Abdominal adiposity rather than age and sex predicts mass and regularity of GH secretion in healthy adults.

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Growth hormone treatment of obese women for 5 wk: effect on body composition and adipose tissue LPL activity

1 reference

12 December 2020

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

1 reference

12 December 2020

Insulin regulation of human hepatic growth hormone receptors: divergent effects on biosynthesis and surface translocation

1 reference

12 December 2020

Gene expression of a truncated and the full-length growth hormone (GH) receptor in subcutaneous fat and skeletal muscle in GH-deficient adults: impact of GH treatment

1 reference

12 December 2020

Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure

1 reference

12 December 2020

Energy and macronutrient intake in growth hormone-deficient adults: the effect of growth hormone replacement

1 reference

12 December 2020

Effects of growth hormone on insulin resistance and atherosclerotic risk factors in obese type 2 diabetic patients with poor glycaemic control.

1 reference

12 December 2020

Treatment of adults with growth hormone (GH) deficiency with recombinant human GH

1 reference

12 December 2020

Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: summary statement of the Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency

1 reference

12 December 2020

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure.

1 reference

12 December 2020

Low-dose growth hormone treatment with diet restriction accelerates body fat loss, exerts anabolic effect and improves growth hormone secretory dysfunction in obese adults

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2013.64

1 reference

28 August 2017

1 reference

PubMed ID

23568441