Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives. (Q38107063)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676629%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives (English)

1 reference

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1 March 2020

main subject

mesenchymal stem cell

1 reference

5

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1 March 2020

Hung Fat Tse

4

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1 March 2020

author name string

Xiaoting Liang

1

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1 March 2020

Yue Ding

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676629%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Yuelin Zhang

3

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1 March 2020

publication date

1 January 2014

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676629%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

23

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676629%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

1045-1059

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1 March 2020

issue

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676629%20AND%20SRC:MED&resulttype=core&format=json

Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury.

1 March 2020

cites work

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Co-infusion of donor bone marrow with host mesenchymal stem cells treats GVHD and promotes vascularized skin allograft survival in rats.

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sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair

21 January 2018

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Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction

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The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair

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Therapeutic applications of mesenchymal stem cells to repair kidney injury

21 January 2018

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Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo

21 January 2018

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Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells

21 January 2018

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Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury.

21 January 2018

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Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury

21 January 2018

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Mesenchymal stem cells rescue cardiomyoblasts from cell death in an in vitro ischemia model via direct cell-to-cell connections

21 January 2018

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Nitric oxide donor upregulation of stromal cell-derived factor-1/chemokine (CXC motif) receptor 4 enhances bone marrow stromal cell migration into ischemic brain after stroke

21 January 2018

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Mesenchymal stromal cells mediate a switch to alternatively activated monocytes/macrophages after acute myocardial infarction.

21 January 2018

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Homing pathways of mesenchymal stromal cells (MSCs) and their role in clinical applications

21 January 2018

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Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

21 January 2018

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Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis.

21 January 2018

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Myocardial CXCR4 expression is required for mesenchymal stem cell mediated repair following acute myocardial infarction

21 January 2018

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Overexpression of phosphoinositide-3-kinase class II alpha enhances mesenchymal stem cell survival in infarcted myocardium.

21 January 2018

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Transplantation with survivin-engineered mesenchymal stem cells results in better prognosis in a rat model of myocardial infarction

21 January 2018

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Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy

21 January 2018

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Tumor angiogenesis: therapeutic implications

21 January 2018

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

21 January 2018

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Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis

21 January 2018

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Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance.

21 January 2018

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Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

21 January 2018

1 reference

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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.

21 January 2018

1 reference

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Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation

21 January 2018

1 reference

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Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction

21 January 2018

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Bone marrow-derived mesenchymal stem cells in fibrin augment angiogenesis in the chronically infarcted myocardium

21 January 2018

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Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

21 January 2018

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Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury

21 January 2018

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

21 January 2018

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Homing and differentiation of mesenchymal stem cells delivered intravenously to ischemic myocardium in vivo: a time-series study.

21 January 2018

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NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke

21 January 2018

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Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion.

21 January 2018

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Roles of Nox1 and other Nox isoforms in cancer development

21 January 2018

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Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokines

21 January 2018

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Stromal cell-derived factor-1 retention and cardioprotection for ischemic myocardium.

21 January 2018

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Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction

21 January 2018

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Successful stem cell therapy using umbilical cord blood-derived multipotent stem cells for Buerger's disease and ischemic limb disease animal model

21 January 2018

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Bone-marrow-derived cells for enhancing collateral development: mechanisms, animal data, and initial clinical experiences

21 January 2018

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Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms.

21 January 2018

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Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model.

21 January 2018

1 reference

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Mesenchymal stromal cells genetically engineered to overexpress IGF-I enhance cell-based gene therapy of renal failure-induced anemia.

21 January 2018

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Cell-based therapy for myocardial ischemia and infarction: pathophysiological mechanisms.

21 January 2018

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Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

21 January 2018

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Cell therapy generates a favourable chemokine gradient for stem cell recruitment into the infarcted heart in rabbits

21 January 2018

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Hypoxia preconditioned mesenchymal stem cells improve vascular and skeletal muscle fiber regeneration after ischemia through a Wnt4-dependent pathway

21 January 2018

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Human umbilical cord mesenchymal stem cells reduce systemic inflammation and attenuate LPS-induced acute lung injury in rats

21 January 2018

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Bcl-2 Engineered MSCs Inhibited Apoptosis and Improved Heart Function

21 January 2018

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Mesenchymal stem cells: a double-edged sword in regulating immune responses

21 January 2018

1 reference

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Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice

21 January 2018

1 reference

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Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Human stanniocalcin-1 suppresses angiotensin II-induced superoxide generation in cardiomyocytes through UCP3-mediated anti-oxidant pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Soluble molecules are key in maintaining the immunomodulatory activity of murine mesenchymal stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Original article anti-oxidant pathways are stimulated by mesenchymal stromal cells in renal repair after ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Microglial activation and chronic neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Pretreating mesenchymal stem cells with interleukin-1β and transforming growth factor-β synergistically increases vascular endothelial growth factor production and improves mesenchymal stem cell-mediated myocardial protection after acute ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function.

21 January 2018

1 reference

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Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Paracrine mechanisms of stem cell reparative and regenerative actions in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Effective engraftment but poor mid-term persistence of mononuclear and mesenchymal bone marrow cells in acute and chronic rat myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Mesenchymal stromal cells protect cancer cells from ROS-induced apoptosis and enhance the Warburg effect by secreting STC1

21 January 2018

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma

21 January 2018

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Bone marrow stem cells regenerate infarcted myocardium

21 January 2018

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Bone marrow cells regenerate infarcted myocardium

21 January 2018

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Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

21 January 2018

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Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway

21 January 2018

1 reference

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Bone marrow mesenchymal stem cells ameliorate hepatic ischemia/reperfusion injuries via inactivation of the MEK/ERK signaling pathway in rats

21 January 2018

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Early homing of adult mesenchymal stem cells in normal and infarcted isolated beating hearts

21 January 2018

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Mesenchymal stem cells and their potential as cardiac therapeutics

21 January 2018

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Cell-to-cell cross-talk between mesenchymal stem cells and cardiomyocytes in co-culture.

21 January 2018

1 reference

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IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

21 January 2018

1 reference

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VEGF improves survival of mesenchymal stem cells in infarcted hearts.

21 January 2018

1 reference

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Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

21 January 2018

1 reference

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Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication

21 January 2018

1 reference

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Stem Cell Mobilization Induced by Subcutaneous Granulocyte-Colony Stimulating Factor to Improve Cardiac Regeneration After Acute ST-Elevation Myocardial Infarction: Result of the Double-Blind, Randomized, Placebo-Controlled Stem Cells in Myocardial I

21 January 2018

1 reference

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Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells

21 January 2018

1 reference

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Mesenchymal stem cells for cardiac regenerative therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells.

21 January 2018

1 reference

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Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen

21 January 2018

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Augmentation of postnatal neovascularization with autologous bone marrow transplantation

21 January 2018

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Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

21 January 2018

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Mesenchymal stem cells overexpressing hepatocyte growth factor (HGF) inhibit collagen deposit and improve bladder function in rat model of bladder outlet obstruction.

21 January 2018

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Human pluripotent stem cell-derived mesenchymal stem cells prevent allergic airway inflammation in mice

21 January 2018

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Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats

21 January 2018

1 reference

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VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart

21 January 2018

1 reference

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Mesenchymal stem cells induce functionally active T-regulatory lymphocytes in a paracrine fashion and ameliorate experimental autoimmune uveitis

21 January 2018

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Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium

21 January 2018

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Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation

21 January 2018

1 reference

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Cardiac Stem Cells Possess Growth Factor-Receptor Systems That After Activation Regenerate the Infarcted Myocardium, Improving Ventricular Function and Long-Term Survival

21 January 2018

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Use of granulocyte-colony stimulating factor during acute myocardial infarction to enhance bone marrow stem cell mobilization in humans: clinical and angiographic safety profile.

21 January 2018

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

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Hypoxic preconditioning attenuates hypoxia/reoxygenation-induced apoptosis in mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Therapeutic effect of mesenchymal stem cells in rats with intracerebral hemorrhage: reduced apoptosis and enhanced neuroprotection.

21 January 2018

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The sepsis seesaw: seeking a heart salve.

21 January 2018

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Human bone marrow mesenchymal stem cells protect catecholaminergic and serotonergic neuronal perikarya and transporter function from oxidative stress by the secretion of glial-derived neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

GMP-adapted overexpression of CXCR4 in human mesenchymal stem cells for cardiac repair.

21 January 2018

1 reference

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Mesenchymal stem cells as a gene therapy carrier for treatment of fibrosarcoma.

21 January 2018

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Mesenchymal stem cells: Mechanisms of immunomodulation and homing

21 January 2018

1 reference

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A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood

21 January 2018

1 reference

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Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10.

21 January 2018

1 reference

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The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Efficient cardiomyogenic differentiation of bone marrow mesenchymal stromal cells by combination of Wnt11 and bone morphogenetic protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts

21 January 2018

1 reference

https://api.crossref.org/works/10.3727%2F096368913X667709

21 January 2018

Identifiers

DOI

10.3727/096368913X667709

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676629%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference