Lysyl oxidase in colorectal cancer (Q38134562)

29 August 2017

Lysyl oxidase in colorectal cancer (English)

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29 August 2017

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Thomas R Cox

1

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Janine T. Erler

object named as

Janine T Erler

series ordinal

2

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publication date

5 September 2013

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American Journal of Physiology - Gastrointestinal and Liver Physiology

29 August 2017

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29 August 2017

305

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29 August 2017

10

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29 August 2017

G659-66

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Lysyl oxidase expression and inhibition in uveal melanoma

29 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The rationale for targeting the LOX family in cancer

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Expression of Gene rrg Is Associated with Reversion of NIH 3Tt3 Transformed by LTR-c-H- ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The proteolytic processing site of the precursor of lysyl oxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Angiogenesis as a therapeutic target

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Role of lysyl oxidase propeptide in secretion and enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Intracellular distribution of the lysyl oxidase propeptide in osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Molecular cloning of human lysyl oxidase and assignment of the gene to chromosome 5q23.3-31.2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

21 January 2018

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Hallmarks of Cancer: The Next Generation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase is required for vascular and diaphragmatic development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Biomarkers to predict the clinical efficacy of bevacizumab in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase: mechanism, regulation and relationship to liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Properties and Function of Lysyl Oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Clinical translation of angiogenesis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Congenital cutis laxa and lysyl oxidase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Combination treatment of Cetuximab and photodynamic therapy in SNU-1041 squamous cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Active lysyl oxidase (LOX) correlates with focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Matrix crosslinking forces tumor progression by enhancing integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Localization and activity of lysyl oxidase within nuclei of fibrogenic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase oxidizes basic fibroblast growth factor and inactivates its mitogenic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Elastic fiber homeostasis requires lysyl oxidase-like 1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Extracellular matrix degradation and remodeling in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Paradoxical roles for lysyl oxidases in cancer--a prospect

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Reduced lysyl oxidase activity in skin fibroblasts from patients with Menkes' syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The lysyl oxidase propeptide interacts with the receptor-type protein tyrosine phosphatase kappa and inhibits β-catenin transcriptional activity in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Palliative chemotherapy for advanced colorectal cancer: systematic review and meta-analysis. Colorectal Cancer Collaborative Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase: properties, regulation and multiple functions in biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

TNF-α increases cardiac fibroblast lysyl oxidase expression through TGF-β and PI3Kinase signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Lysyl oxidase propeptide inhibits FGF-2-induced signaling and proliferation of osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00425.2012

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00425.2012

1 reference

29 August 2017

1 reference

PubMed ID

24008360