Targeting CCL5 in inflammation (Q38148785)

29 August 2017

Targeting CCL5 in inflammation (English)

1 reference

29 August 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Rodrigo Guabiraba

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Mauro Martins Teixeira

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Remo Castro Russo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

3 October 2013

1 reference

Expert Opinion on Therapeutic Targets

29 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

1439-1460

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

Origin and physiological roles of inflammation

31 May 2020

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The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.

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Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease

21 January 2018

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A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection

21 January 2018

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MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.

21 January 2018

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CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases

21 January 2018

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A broad spectrum secreted chemokine binding protein encoded by a herpesvirus

21 January 2018

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Poxvirus genomes encode a secreted, soluble protein that preferentially inhibits beta chemokine activity yet lacks sequence homology to known chemokine receptors

21 January 2018

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C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis

21 January 2018

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Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

21 January 2018

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CXC and CC chemokines form mixed heterodimers: association free energies from molecular dynamics simulations and experimental correlations

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Chemokine receptor oligomerization: functional considerations.

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How chemokines invite leukocytes to dance

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Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues

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Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines

21 January 2018

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The chemokine receptor D6 limits the inflammatory response in vivo

21 January 2018

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Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

21 January 2018

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Chemokine regulation of inflammation during acute viral infection

21 January 2018

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Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation

21 January 2018

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RANTES: a versatile and controversial chemokine

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Functional antagonism of chemokine receptor CCR1 reduces mortality in acute pneumovirus infection in vivo

21 January 2018

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Role for nonstructural protein 1 of severe acute respiratory syndrome coronavirus in chemokine dysregulation

21 January 2018

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Innate immune response of human alveolar macrophages during influenza A infection

21 January 2018

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Pathology, molecular biology, and pathogenesis of avian influenza A (H5N1) infection in humans

21 January 2018

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Seasonal and pandemic influenza H1N1 viruses induce differential expression of SOCS-1 and RIG-I genes and cytokine/chemokine production in macrophages.

21 January 2018

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CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection

21 January 2018

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A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination

21 January 2018

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Microglial cells initiate vigorous yet non-protective immune responses during HSV-1 brain infection.

21 January 2018

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The role of chemokines in the pathogenesis of neurotropic flaviviruses

21 January 2018

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Astrocytes modulate the chemokine network in a pathogen-specific manner.

21 January 2018

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Astrocytes play a key role in activation of microglia by persistent Borna disease virus infection

21 January 2018

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Gamma interferon signaling in macrophage lineage cells regulates central nervous system inflammation and chemokine production

21 January 2018

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Rabies virus-induced activation of mitogen-activated protein kinase and NF-kappaB signaling pathways regulates expression of CXC and CC chemokine ligands in microglia

21 January 2018

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Rabies Virus Nucleoprotein Functions To Evade Activation of the RIG-I-Mediated Antiviral Response

21 January 2018

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The roles of chemokines in rabies virus infection: overexpression may not always be beneficial

21 January 2018

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Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection

21 January 2018

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CCR5 deficiency increases risk of symptomatic West Nile virus infection

21 January 2018

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A deletion in the chemokine receptor 5 (CCR5) gene is associated with tickborne encephalitis

21 January 2018

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Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis

21 January 2018

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The role of chemokines during herpes simplex virus-1 infection

21 January 2018

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Subversion of cytokine networks by virally encoded decoy receptors

21 January 2018

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A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

21 January 2018

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Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation

21 January 2018

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Human cytomegalovirus clinical strain-specific microRNA miR-UL148D targets the human chemokine RANTES during infection

21 January 2018

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Human cytomegalovirus encodes a highly specific RANTES decoy receptor

21 January 2018

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Interaction between RANTES promoter variant and CCR5Delta32 favors recovery from hepatitis B.

21 January 2018

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Treatment of yellow fever

21 January 2018

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Case of yellow fever vaccine--associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES genes

21 January 2018

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The impact of dengue haemorrhagic fever on liver function

21 January 2018

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Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever.

21 January 2018

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IL-22 modulates IL-17A production and controls inflammation and tissue damage in experimental dengue infection

21 January 2018

1 reference

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Experimental infection with Schistosoma mansoni in CCR5-deficient mice is associated with increased disease severity, as CCR5 plays a role in controlling granulomatous inflammation

21 January 2018

1 reference

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Periportal fibrosis in human Schistosoma mansoni infection is associated with low IL-10, low IFN-gamma, high TNF-alpha, or low RANTES, depending on age and gender

21 January 2018

1 reference

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Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responses and chemokines in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis

21 January 2018

1 reference

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T cell homing to epithelial barriers in allergic disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Role of chemokines in the pathogenesis of asthma

21 January 2018

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RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge

21 January 2018

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The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

21 January 2018

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Respiratory syncytial virus-induced CCL5/RANTES contributes to exacerbation of allergic airway inflammation

21 January 2018

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Asthma phenotypes in Japanese adults - their associations with the CCL5 and ADRB2 genotypes

21 January 2018

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Chemokines in atherosclerosis: an update

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Dynamic interplay of transcriptional machinery and chromatin regulates "late" expression of the chemokine RANTES in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Y-box binding protein-1 controls CC chemokine ligand-5 (CCL5) expression in smooth muscle cells and contributes to neointima formation in atherosclerosis-prone mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in non-obese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

21 January 2018

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Molecular mechanisms of blood vessel formation

21 January 2018

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Role of the chemokines CCL3/MIP-1 alpha and CCL5/RANTES in sponge-induced inflammatory angiogenesis in mice

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans

21 January 2018

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Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment

21 January 2018

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Papillary carcinoma of the thyroid: hepatocyte growth factor (HGF) stimulates tumor cells to release chemokines active in recruiting dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

A dual role for tumor-derived chemokine RANTES (CCL5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Homeostatic chemokine receptors and organ-specific metastasis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

CCL5 secreted by senescent aged fibroblasts induces proliferation of prostate epithelial cells and expression of genes that modulate angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Essential roles of the CC chemokine ligand 3-CC chemokine receptor 5 axis in bleomycin-induced pulmonary fibrosis through regulation of macrophage and fibrocyte infiltration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Early application of Met-RANTES ameliorates chronic allograft nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Ccr1 deficiency reduces inflammatory remodelling and preserves left ventricular function after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Met-RANTES reduces endothelial progenitor cell homing to activated (glomerular) endothelium in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Tolerability and efficacy of inhaled AZD4818, a CCR1 antagonist, in moderate to severe COPD patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.837886

Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma

21 January 2018

1 reference

12 December 2020

Studies on disease-modifying antirheumatic drugs. III. Bone resorption inhibitory effects of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl) quinoline-3-carboxylate (TAK-603) and related compounds

1 reference

12 December 2020

A novel highly potent therapeutic antibody neutralizes multiple human chemokines and mimics viral immune modulation

1 reference

12 December 2020

Anti-inflammatory drug development: Broad or specific chemokine receptor antagonists?

1 reference

12 December 2020

C-C chemokine-induced eosinophil chemotaxis during allergic airway inflammation

1 reference

12 December 2020

The source and role of RANTES in interstitial lung disease

1 reference

12 December 2020

A Novel RANTES Antagonist Prevents Progression of Established Atherosclerotic Lesions in Mice

1 reference

12 December 2020

Treatment of established asthma in a murine model using CpG oligodeoxynucleotides

1 reference

12 December 2020

Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor

1 reference

12 December 2020

Deficiency in CCR5 but not CCR1 protects against neointima formation in atherosclerosis-prone mice: involvement of IL-10

1 reference

12 December 2020

Expression of RANTES mRNA and protein in airways of patients with mild asthma

1 reference

12 December 2020

Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function

1 reference

12 December 2020

Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1

1 reference

12 December 2020

Beneficial effects of CCR1 blockade on the progression of chronic renal allograft damage

1 reference

12 December 2020

A human T cell-specific molecule is a member of a new gene family

1 reference

12 December 2020

Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium

1 reference

12 December 2020

Ticks produce highly selective chemokine binding proteins with antiinflammatory activity

1 reference

12 December 2020

Differential expression and cross-regulatory function of RANTES during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granulomatous inflammation

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12 December 2020

Sustained inhibition of corneal neovascularization by genetic ablation of CCR5

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12 December 2020

Significantly increased CCL5/RANTES and CCR7 mRNA levels in localized scleroderma

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12 December 2020

Ccr5 But Not Ccr1 Deficiency Reduces Development of Diet-Induced Atherosclerosis in Mice

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12 December 2020

A chimeric MIP-1alpha/RANTES protein demonstrates the use of different regions of the RANTES protein to bind and activate its receptors

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12 December 2020

Increased expression of mRNA encoding RANTES and MCP-3 in the bronchial mucosa in atopic asthma

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12 December 2020

The role of chemokines as inflammatory mediators in chronic hepatitis C virus infection

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12 December 2020

Chemokines and T lymphocyte recruitment to lymph nodes in HIV infection.

1 reference

12 December 2020

Transfer of the enhancing effect of respiratory syncytial virus infection on subsequent allergic airway sensitization by T lymphocytes.

1 reference

12 December 2020

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The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24090198%20AND%20SRC:MED&resulttype=core&format=json