Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease (Q38150700)

29 August 2017

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease (English)

1 reference

29 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105077%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Helen Ball

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105077%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Nicholas H Hunt

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105077%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

9 October 2013

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29 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105077%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

45

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105077%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

1319-1329

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105077%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105077%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00726-013-1602-1

1 June 2020

exact match

0 references

cites work

Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Kynurenine as an Intermediate in the Formation of Nicotinic Acid from Tryptophane by Neurospora

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-[3-benzo(b)thienyl]-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Reassessment of the reaction mechanism in the heme dioxygenases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Antioxidant activities of some tryptophan metabolites: possible implication for inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Altered kynurenine metabolism correlates with infarct volume in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Early kynurenergic impairment in Huntington's disease and in a transgenic animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Identification of tryptophan 2,3-dioxygenase RNA in rodent brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Immunopathogenesis of cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Prevention of allogeneic fetal rejection by tryptophan catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

The human indoleamine 2,3-dioxygenase gene and related human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Kynurenine pathway abnormalities in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 1. Norharman and 4-phenylimidazole binding to the enzyme as inhibitors and heme ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Novel 1-alkyl-tryptophan derivatives downregulate IDO1 and IDO2 mRNA expression induced by interferon-gamma in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Kynurenine is an endothelium-derived relaxing factor produced during inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Evolution of vertebrate indoleamine 2,3-dioxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1

Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1602-1