The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. (Q38159859)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24189125%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

20 October 2020

The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24189125%20AND%20SRC:MED&resulttype=core&format=json

regulation of gene expression

29 February 2020

main subject

Aspergillus fumigatus

0 references

1 reference

8 September 2019

1 reference

22 October 2019

1 reference

20 October 2020

Karthik Mosur Krishnan

1

1 reference

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29 February 2020

David S Askew

2

1 reference

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29 February 2020

author name string

Karthik Krishnan

1

1 reference

30 August 2017

David S Askew

2

1 reference

30 August 2017

18 October 2013

1 reference

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29 February 2020

15 February 2014

1 reference

20 October 2020

4 references

8 September 2019

22 October 2019

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29 February 2020

20 October 2020

5

1 reference

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29 February 2020

issue

2

1 reference

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29 February 2020

page(s)

334-340

1 reference

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Creative Commons Attribution-NonCommercial 3.0 Unported

29 February 2020

copyright license

3 references

8 September 2019

22 October 2019

Essential roles of the Kar2/BiP molecular chaperone downstream of the UPR pathway in Cryptococcus neoformans

20 October 2020

cites work

1 reference

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Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen Aspergillus fumigatus

6 September 2017

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6 September 2017

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Cleaning up: ER-associated degradation to the rescue

6 September 2017

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Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

6 September 2017

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Structural basis of the unfolded protein response

6 September 2017

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6 September 2017

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6 September 2017

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Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing

6 September 2017

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6 September 2017

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Invasive fungal infections in solid organ transplant recipients

6 September 2017

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Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

6 September 2017

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Hypoxia and fungal pathogenesis: to air or not to air?

6 September 2017

1 reference

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The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway

6 September 2017

1 reference

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InterfERing with endoplasmic reticulum stress

6 September 2017

1 reference

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Disruption of the phospholipase D gene attenuates the virulence of Aspergillus fumigatus

6 September 2017

1 reference

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HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus

6 September 2017

1 reference

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Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans

6 September 2017

1 reference

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Iron homeostasis--Achilles' heel of Aspergillus fumigatus?

6 September 2017

1 reference

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Ccr4 promotes resolution of the endoplasmic reticulum stress response during host temperature adaptation in Cryptococcus neoformans

6 September 2017

1 reference

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Shaping the fungal adaptome--stress responses of Aspergillus fumigatus

6 September 2017

1 reference

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Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease

6 September 2017

1 reference

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The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level

6 September 2017

1 reference

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Secretion stress and antifungal resistance: an Achilles' heel of Aspergillus fumigatus?

6 September 2017

1 reference

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Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals

6 September 2017

1 reference

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Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

6 September 2017

1 reference

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Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

6 September 2017

1 reference

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A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus

6 September 2017

1 reference

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A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus

6 September 2017

1 reference

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Sub-telomere directed gene expression during initiation of invasive aspergillosis

6 September 2017

1 reference

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Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albicans

6 September 2017

1 reference

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Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger

6 September 2017

1 reference

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Genome sequencing and analysis of Aspergillus oryzae

6 September 2017

1 reference

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Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

6 September 2017

1 reference

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Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

6 September 2017

1 reference

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Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.

6 September 2017

1 reference

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Thermotolerance and virulence of Aspergillus fumigatus: role of the fungal nucleolus

6 September 2017

1 reference

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The transcription factor HACA mediates the unfolded protein response in Aspergillus niger, and up-regulates its own transcription

6 September 2017

1 reference

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Activation mechanisms of the HAC1-mediated unfolded protein response in filamentous fungi

6 September 2017

1 reference

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The direct cost and incidence of systemic fungal infections

6 September 2017

1 reference

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response

6 September 2017

1 reference

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Conservation of eukaryotic sterol homeostasis: new insights from studies in budding yeast

6 September 2017

1 reference

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

6 September 2017

1 reference

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The role of iron in protozoan and fungal infectious diseases

6 September 2017

1 reference

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Purification and characterization of an elastinolytic metalloprotease from Aspergillus fumigatus and immunoelectron microscopic evidence of secretion of this enzyme by the fungus invading the murine lung

6 September 2017

1 reference

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Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue

6 September 2017

1 reference

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Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

HacA-dependent transcriptional switch releases hacA mRNA from a translational block upon endoplasmic reticulum stress

23 June 2018

1 reference

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Aspergillosis due to voriconazole highly resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles

23 June 2018

1 reference

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Naming Aspergillus species: progress towards one name for each species

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

Hospital costs and outcomes among intravenous antifungal therapies for patients with invasive aspergillosis in the United States

31 August 2018

1 reference

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31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3956511

HACA, the transcriptional activator of the unfolded protein response (UPR) in Aspergillus niger, binds to partly palindromic UPR elements of the consensus sequence 5'-CAN(G/A)NTGT/GCCT-3'

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24189125

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of the 33-kDa alkaline protease of Aspergillus fumigatus in vitro and in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24189125

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/VIRU.26571

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24189125%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24189125%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

24189125

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24189125%20AND%20SRC:MED&resulttype=core&format=json