TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis (Q38164289)

30 August 2017

TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis (English)

1 reference

30 August 2017

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Barry Flutter

1

1 reference

PubMed ID

24254490

30 August 2017

Frank O Nestle

series ordinal

2

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PubMed ID

24254490

30 August 2017

language of work or name

English

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publication date

20 November 2013

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European Journal of Immunology

30 August 2017

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30 August 2017

43

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30 August 2017

3138-3146

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30 August 2017

12

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Mouse models of psoriasis.

30 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Aldara activates TLR7-independent immune defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Modification of immunological responses and clinical disease during topical R-837 treatment of genital HSV-2 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Self-administered topical 5% imiquimod cream for external anogenital warts. HPV Study Group. Human PapillomaVirus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Treatment of genital warts with an immune-response modifier (imiquimod).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Therapeutic response of basal cell carcinoma to the immune response modifier imiquimod 5% cream

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Imiquimod for actinic keratosis: systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Immune modulation and apoptosis induction: two sides of the antitumoral activity of imiquimod

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-1R1 signaling facilitates Munro's microabscess formation in psoriasiform imiquimod-induced skin inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-17-producing γδ T cells and innate lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Short‐course therapy with imiquimod 5% cream for solar keratoses: A randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Genome-wide expression profiling of five mouse models identifies similarities and differences with human psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

IL-23: one cytokine in control of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Genetics and pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Substantial alterations of the cutaneous bacterial biota in psoriatic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Compartmentalized control of skin immunity by resident commensals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Remission of psoriasis after allogeneic, but not autologous, hematopoietic stem-cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Impaired mast cell-driven immune responses in mice lacking the transcription factor NFATc2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Involvement of tyrosine kinase-2 in both the IL-12/Th1 and IL-23/Th17 axes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

Skin immune sentinels in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Development of a topically active imiquimod formulation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Imiquimod for the treatment of actinic keratosis: A meta-analysis of randomized controlled trials

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Imiquimod, a topical immune response modifier, induces migration of Langerhans cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Psoriasis and HLA-Cw6

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343801

7 January 2021

Identifiers

DOI

10.1002/EJI.201343801

1 reference

30 August 2017

1 reference

PubMed ID

24254490