The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets (Q38167634)

30 August 2017

The peculiarities of the SDF-1/CXCL12 system: in some cells, CXCR4 and CXCR7 sing solos, in others, they sing duets (English)

1 reference

30 August 2017

Malte Puchert

1

1 reference

PubMed ID

24292718

30 August 2017

Jürgen Engele

series ordinal

2

1 reference

30 August 2017

29 November 2013

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30 August 2017

Cell and Tissue Research

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30 August 2017

355

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30 August 2017

2

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30 August 2017

239-253

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https://scigraph.springernature.com/pub.10.1007/s00441-013-1747-y

30 August 2017

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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

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PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling

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Changes in satellite cells in human skeletal muscle after a single bout of high intensity exercise

21 January 2018

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Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

21 January 2018

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CXCR4 inhibitors: tumor vasculature and therapeutic challenges.

21 January 2018

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CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.

21 January 2018

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Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

21 January 2018

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CXCL12/CXCR4 promotes motility and proliferation of glioma cells

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Myocardial CXCR4 expression is required for mesenchymal stem cell mediated repair following acute myocardial infarction

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A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors.

21 January 2018

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CXCR4 mediates the proliferation of glioblastoma progenitor cells

21 January 2018

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Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice

21 January 2018

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Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents.

21 January 2018

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Activation of CXCR7 receptor promotes oligodendroglial cell maturation.

21 January 2018

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Chemokine expression and control of muscle cell migration during myogenesis

21 January 2018

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Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas

21 January 2018

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Blockade of the Stromal Cell–Derived Factor-1/CXCR4 Axis AttenuatesIn vivoTumor Growth by Inhibiting Angiogenesis in a Vascular Endothelial Growth Factor–Independent Manner

21 January 2018

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Multiple actions of the chemokine stromal cell-derived factor-1alpha on neuronal activity

21 January 2018

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CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney

21 January 2018

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21 January 2018

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21 January 2018

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The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects

21 January 2018

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SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus

21 January 2018

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Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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Expression and function of the SDF-1 chemokine receptors CXCR4 and CXCR7 during mouse limb muscle development and regeneration.

21 January 2018

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Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

21 January 2018

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Expression and regulation of the orphan receptor RDC1 and its putative ligand in human dendritic and B cells

21 January 2018

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The relationship between SDF-1alpha/CXCR4 and neural stem cells appearing in damaged area after traumatic brain injury in rats.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Cellular adaptation of the trapezius muscle in strength-trained athletes.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The multiple faces of CXCL12 (SDF-1alpha) in the regulation of immunity during health and disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The chemokine CXCL12 promotes survival of postmitotic neurons by regulating Rb protein.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Differential effects of CXCR4 antagonists on the survival and proliferation of myeloid leukemia cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7 mediates SDF1-induced melanocyte migration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Multiple roles of chemokine CXCL12 in the central nervous system: a migration from immunology to neurobiology

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Chemokine receptor CXCR4 signaling modulates the growth factor-induced cell cycle of self-renewing and multipotent neural progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 and CXCR7 form a functional receptor unit for SDF-1/CXCL12 in primary rodent microglia

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Vascular gene expression patterns are conserved in primary and metastatic brain tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Expression and functional heterogeneity of chemokine receptors CXCR4 and CXCR7 in primary patient-derived glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7 silencing attenuates cell adaptive response to stromal cell derived factor 1α after hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Induction of C-X-C chemokine receptor type 7 (CXCR7) switches stromal cell-derived factor-1 (SDF-1) signaling and phagocytic activity in macrophages linked to atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7: a novel tumor endothelial marker in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Expression of stromal cell-derived factor-1 and of its receptor CXCR4 in liver regeneration from oval cells in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Dasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCL12 receptor preference, signal transduction, biological response and the expression of 5T4 oncofoetal glycoprotein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Induction of myogenic differentiation by SDF-1 via CXCR4 and CXCR7 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCL12 in control of neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Molecular cloning and structure of a pre-B-cell growth-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7 functions as a scavenger for CXCL12 and CXCL11

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7 is an active component of SDF-1 signalling in astrocytes and Schwann cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 enhances engraftment of muscle progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Teaching old receptors new tricks: biasing seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Mitogenic signaling pathways induced by G protein-coupled receptors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCL12, CXCR4 and CXCR7 expression in brain metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Regional and cellular localization of the CXCl12/SDF-1 chemokine receptor CXCR7 in the developing and adult rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7 protein expression in human adult brain and differentiated neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Stromal cell-derived factor-1 alpha promotes neuroprotection, angiogenesis, and mobilization/homing of bone marrow-derived cells in stroke rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The bone marrow microenvironment and leukemia: biology and therapeutic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The chemokine stromal cell-derived factor-1/CXCL12 activates the nigrostriatal dopamine system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7: a new SDF-1-binding receptor in contrast to normal CD34(+) progenitors is functional and is expressed at higher level in human malignant hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR7, CXCR4 and CXCL12: an eccentric trio?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Expression and function of CXCR7 in the mouse forebrain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Aberrant proliferation in CXCR7+ endothelial cells via degradation of the retinoblastoma protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Chemokine receptors: signposts to brain development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Localization of CXCR4 in the forebrain of the adult rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Increased susceptibility to severe chronic liver damage in CXCR4 conditional knock-out mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Molecular signatures of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 and CXCR7 have distinct functions in regulating interneuron migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The CXCR7 chemokine receptor promotes B-cell retention in the splenic marginal zone and serves as a sink for CXCL12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Overexpression of SDF-1α enhanced migration and engraftment of cardiac stem cells and reduced infarcted size via CXCR4/PI3K pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Roles of chemokine CXCL12 and its receptors in ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Chemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

C-X-C chemokine receptor 7: a functionally associated molecular marker for bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

A novel mechanism by which SDF-1β protects cardiac cells from palmitate-induced endoplasmic reticulum stress and apoptosis via CXCR7 and AMPK/p38 MAPK-mediated interleukin-6 generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCR4 is a major chemokine receptor on glioma cells and mediates their survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Chemokine CXCL12 and its receptors in the developing central nervous system: emerging themes and future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Conditional inactivation of the CXCR4 receptor in osteoprecursors reduces postnatal bone formation due to impaired osteoblast development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Homeostatic chemokine receptors and organ-specific metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-013-1747-Y

10.1007/S00441-013-1747-Y

21 January 2018

Identifiers

DOI

1 reference

PubMed ID

24292718

Dimensions Publication ID

30 August 2017

0 references

1 reference

PubMed ID

24292718