Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy (Q38198859)

30 August 2017

Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy (English)

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30 August 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662279%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Julian R F Walters

series ordinal

1

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30 August 2017

language of work or name

English

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publication date

25 March 2014

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Nature Reviews Gastroenterology & Hepatology

30 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662279%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662279%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

426-434

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662279%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

7

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https://scigraph.springernature.com/pub.10.1038/nrgastro.2014.32

11 June 2020

exact match

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cites work

Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Cholestyramine treatment of diarrhea associated with ileal resection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Idiopathic bile acid catharsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Guidelines for the investigation of chronic diarrhoea, 2nd edition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Primary bile acid diarrhoea without an ileal carrier defect: quantification of active bile acid transport across the ileal brush border membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Normal or increased bile acid uptake in isolated mucosa from patients with bile acid malabsorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

A new mechanism for bile acid diarrhea: defective feedback inhibition of bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Chronic diarrhea caused by idiopathic bile acid malabsorption: an explanation at last.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Defining primary bile acid diarrhea: making the diagnosis and recognizing the disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Prevalence of, and predictors of, bile acid malabsorption in outpatients with chronic diarrhea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid malabsoption: a forgotten diagnosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Methods for diagnosis of bile acid malabsorption in clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Assessment of ileal function by abdominal counting of the retention of a gamma emitting bile acid analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

75Se HCAT test in the detection of bile acid malabsorption in functional diarrhoea and its correlation with small bowel transit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Managing bile acid diarrhoea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Recycling rate of bile acids in the enterohepatic recirculation as a major determinant of whole body 75SeHCAT retention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid malabsorption: an under-investigated differential diagnosis in patients presenting with diarrhea predominant irritable bowel syndrome type symptoms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

A survey of the clinical use of SeHCAT in the UK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid malabsorption in patients with chronic diarrhoea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Serum 7 alpha-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid malabsorption as a cause of chronic diarrhea: diagnostic value of 7alpha-hydroxy-4-cholesten-3-one in serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

An evaluation of the use of serum 7-alpha-hydroxycholestenone as a diagnostic test of bile acid malabsorption causing watery diarrhea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Measurement of serum 7alpha-hydroxy-4-cholesten-3-one (or 7alphaC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Increased bile acid biosynthesis is associated with irritable bowel syndrome with diarrhea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Accurate enzymatic measurement of fecal bile acids in patients with malabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bowel functions, fecal unconjugated primary and secondary bile acids, and colonic transit in patients with irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Effect of conjugated dihydroxy bile salts on electrolyte transport in rat colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

21 January 2018

Physiology of FGF15/19

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Fibroblast Growth Factor 19 and 7α-Hydroxy-4-Cholesten-3-one in the Diagnosis of Patients With Possible Bile Acid Diarrhea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Antibody-mediated inhibition of fibroblast growth factor 19 results in increased bile acids synthesis and ileal malabsorption of bile acids in cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

A Klothoβ variant mediates protein stability and associates with colon transit in irritable bowel syndrome with diarrhea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Pharmacogenetics of the effects of colesevelam on colonic transit in irritable bowel syndrome with diarrhea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid malabsorption in inflammatory bowel disease: assessment by serum markers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Altered enterohepatic circulation of bile acids in Crohn's disease and their clinical significance: a new perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Fibroblast growth factor-19: development, analytical characterization and clinical evaluation of a new ELISA test

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

The role of bile after Roux-en-Y gastric bypass in promoting weight loss and improving glycaemic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Regulation of bile acid synthesis by fat-soluble vitamins A and D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

A G protein-coupled receptor responsive to bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Identification of membrane-type receptor for bile acids (M-BAR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Effects of chemical modification of ursodeoxycholic acid on TGR5 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Fibroblast growth factor 19 in patients with bile acid diarrhoea: a prospective comparison of FGF19 serum assay and SeHCAT retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Application of a novel tool for diagnosing bile acid diarrhoea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Bile acid malabsorption investigated by selenium-75-homocholic acid taurine ((75)SeHCAT) scans: causes and treatment responses to cholestyramine in 298 patients with chronic watery diarrhoea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Classification of the sequelae of bowel resection for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32

Accelerated regional bowel transit and overweight shown in idiopathic bile acid malabsorption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2014.32