Novel molecular aspects of ghrelin and leptin in the control of adipobiology and the cardiovascular system (Q38200787)

22 December 2017

9 references

19 March 2019

24 March 2019

17 June 2019

10 October 2019

11 October 2019

17 November 2019

20 November 2019

18 December 2020

5 July 2021

Novel molecular aspects of ghrelin and leptin in the control of adipobiology and the cardiovascular system (English)

1 reference

22 December 2017

main subject

cardiovascular disease

7 references

19 March 2019

24 March 2019

17 June 2019

10 October 2019

11 October 2019

17 November 2019

20 November 2019

7 references

19 March 2019

24 March 2019

17 June 2019

10 October 2019

11 October 2019

17 November 2019

20 November 2019

1 reference

10 October 2019

1 reference

11 October 2019

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17 November 2019

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20 November 2019

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18 December 2020

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5 July 2021

1

1 reference

22 December 2017

author name string

Amaia Rodríguez

series ordinal

1

1 reference

PubMed ID

24685565

30 August 2017

language of work or name

1 reference

26 March 2014

10 references

22 December 2017

19 March 2019

24 March 2019

17 June 2019

10 October 2019

11 October 2019

17 November 2019

20 November 2019

18 December 2020

5 July 2021

10 references

22 December 2017

19 March 2019

24 March 2019

17 June 2019

10 October 2019

11 October 2019

17 November 2019

20 November 2019

18 December 2020

5 July 2021

7

1 reference

22 December 2017

issue

2

1 reference

22 December 2017

page(s)

82-95

1 reference

22 December 2017

Creative Commons Attribution-NonCommercial 3.0 Unported

copyright license

9 references

19 March 2019

24 March 2019

17 June 2019

10 October 2019

11 October 2019

17 November 2019

20 November 2019

18 December 2020

on focus list of Wikimedia project

5 July 2021

ScienceSource

0 references

cites work

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23 June 2018

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The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects

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Cardioprotective effect of ghrelin in cardiopulmonary bypass involves a reduction in inflammatory response

23 June 2018

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Vasodilator effect of ghrelin in the rat aorta

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The ghrelin O-acyltransferase-ghrelin system reduces TNF-α-induced apoptosis and autophagy in human visceral adipocytes.

23 June 2018

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Transcriptional analysis of brown adipose tissue in leptin-deficient mice lacking inducible nitric oxide synthase: evidence of the role of Med1 in energy balance

23 June 2018

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Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium

23 June 2018

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Bariatric surgery to unload the stressed heart: a metabolic hypothesis

23 June 2018

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Ghrelin protects H9c2 cardiomyocytes from angiotensin II-induced apoptosis through the endoplasmic reticulum stress pathway

23 June 2018

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Preproghrelin expression is a key target for insulin action on adipogenesis

23 June 2018

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Sixteen years and counting: an update on leptin in energy balance

23 June 2018

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Aquaglyceroporins serve as metabolic gateways in adiposity and insulin resistance control

23 June 2018

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The central Sirtuin 1/p53 pathway is essential for the orexigenic action of ghrelin

23 June 2018

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National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

23 June 2018

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Insulin- and leptin-mediated control of aquaglyceroporins in human adipocytes and hepatocytes is mediated via the PI3K/Akt/mTOR signaling cascade

23 June 2018

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Effect of desacyl ghrelin, obestatin and related peptides on triglyceride storage, metabolism and GHSR signaling in 3T3-L1 adipocytes

23 June 2018

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Leptin inhibits the proliferation of vascular smooth muscle cells induced by angiotensin II through nitric oxide-dependent mechanisms

23 June 2018

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Deletion of inducible nitric-oxide synthase in leptin-deficient mice improves brown adipose tissue function

23 June 2018

1 reference

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Changes in acyl ghrelin, des-acyl ghrelin, and ratio of acyl ghrelin to total ghrelin with short-term refeeding in female inpatients with restricting-type anorexia nervosa

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Ghrelin gene products and the regulation of food intake and gut motility

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Hypothalamic nutrient sensing in the control of energy homeostasis

23 June 2018

1 reference

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Resistance to acute NO-mimetic and EDHF-mimetic effects of leptin in the metabolic syndrome

23 June 2018

1 reference

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Membrane trafficking of aquaporin 3 induced by epinephrine

23 June 2018

1 reference

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The bone-adipose axis in obesity and weight loss.

23 June 2018

1 reference

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Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone

23 June 2018

1 reference

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Visceral and subcutaneous adiposity: are both potential therapeutic targets for tackling the metabolic syndrome?

23 June 2018

1 reference

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Fasting-induced increases in aquaporin 7 and adipose triglyceride lipase mRNA expression in adipose tissue are attenuated by peroxisome proliferator-activated receptor alpha deficiency

23 June 2018

1 reference

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The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor

23 June 2018

1 reference

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Role of aquaporin-7 in the pathophysiological control of fat accumulation in mice

23 June 2018

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The inhibitory effect of leptin on angiotensin II-induced vasoconstriction is blunted in spontaneously hypertensive rats

23 June 2018

1 reference

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Intracellular signalling pathways activated by leptin

23 June 2018

1 reference

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Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study

23 June 2018

1 reference

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Obesity-associated hypertension: new insights into mechanisms.

23 June 2018

1 reference

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The adipose tissue as a source of vasoactive factors

23 June 2018

1 reference

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Growth hormone releasing peptide (ghrelin) is synthesized and secreted by cardiomyocytes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin.

23 June 2018

1 reference

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Leptin in the CNS: much more than a satiety signal.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Cardiovascular risks in obesity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Leptin inhibits angiotensin II-induced intracellular calcium increase and vasoconstriction in the rat aorta

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/STAT pathway.

23 June 2018

1 reference

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A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans

23 June 2018

1 reference

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Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue

23 June 2018

1 reference

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Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes.

23 June 2018

1 reference

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Obesity as a medical problem

23 June 2018

1 reference

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Ghrelin is a growth-hormone-releasing acylated peptide from stomach

23 June 2018

1 reference

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Sex differences in circulating human leptin pulse amplitude: clinical implications

23 June 2018

1 reference

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High plasma immunoreactive leptin level in essential hypertension

23 June 2018

1 reference

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Leptin increases uncoupling protein expression and energy expenditure

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

The leptin haemopoietic cytokine fold is stabilized by an intrachain disulfide bond

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

A receptor in pituitary and hypothalamus that functions in growth hormone release

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Positional cloning of the mouse obese gene and its human homologue

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Threading analysis suggests that the obese gene product may be a helical cytokine

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Exposure to a high-fat diet during development alters leptin and ghrelin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Leptin promotes neointima formation and smooth muscle cell proliferation via NADPH oxidase activation and signalling in caveolin-rich microdomains.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Gastric bypass does not normalize obesity-related changes in ghrelin profile and leads to higher acylated ghrelin fraction.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Obesity: the gateway to ill health - an EASO position statement on a rising public health, clinical and scientific challenge in Europe

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Altered myocardial expression of ghrelin and its receptor (GHSR-1a) in patients with severe heart failure.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Acylated and nonacylated ghrelin levels and their associations with insulin resistance in obese and normal weight children with metabolic syndrome.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Impaired adiponectin-AMPK signalling in insulin-sensitive tissues of hypertensive rats

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Plasma acylated ghrelin levels are higher in patients with chronic atrophic gastritis.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

The obestatin receptor (GPR39) is expressed in human adipose tissue and is down-regulated in obesity-associated type 2 diabetes mellitus.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Leptin inhibits cell growth of human vascular smooth muscle cells.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

The negative association between plasma ghrelin and IGF-I is modified by obesity, insulin resistance and type 2 diabetes

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Effects of chronic nitric oxide inhibition on the renal excretory response to leptin

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Molecular characterization of chicken growth hormone secretagogue receptor gene

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Leptin stimulates rat aortic smooth muscle cell proliferation and migration.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Circulating ghrelin levels are decreased in human obesity.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Purification and characterization of rat des-Gln14-Ghrelin, a second endogenous ligand for the growth hormone secretagogue receptor

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Leptin is a four-helix bundle: secondary structure by NMR.

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Perivascular Adipose Tissue and Mesenteric Vascular Function in Spontaneously Hypertensive Rats

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Visceral Fat Is an Independent Predictor of All-cause Mortality in Men*

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5644879

Leptin promotes the mobilization of vascular progenitor cells and neovascularization by NOX2-mediated activation of MMP9

3 December 2018

1 reference

12 December 2020

American Heart Association call to action: obesity as a major risk factor for coronary heart disease. AHA Nutrition Committee

1 reference

12 December 2020

Plasma levels of acylated and total ghrelin in pediatric patients with chronic kidney disease

1 reference

12 December 2020

Circulating ghrelin levels in obese women: a possible association with hypertension

1 reference

12 December 2020

One dose of ghrelin prevents the acute and sustained increase in cardiac sympathetic tone after myocardial infarction

1 reference

12 December 2020

Serum ghrelin level and TNF-α/ghrelin ratio in patients with previous myocardial infarction

1 reference

12 December 2020

On the processing of proghrelin to ghrelin

1 reference

12 December 2020

Pivotal role of nitric oxide in the control of blood pressure after leptin administration

1 reference

12 December 2020

Association of plasma acylated ghrelin with blood pressure and left ventricular mass in patients with metabolic syndrome

1 reference

12 December 2020

Ghrelin inhibits vascular superoxide production in spontaneously hypertensive rats

1 reference

12 December 2020

Central ghrelin modulates sympathetic activity in conscious rabbits

1 reference

12 December 2020

The Inhibitory Effect of Leptin on Angiotensin II-Induced Vasoconstriction in Vascular Smooth Muscle Cells Is Mediated via a Nitric Oxide-Dependent Mechanism

1 reference

12 December 2020

Elevated circulating leptin levels in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin

1 reference

12 December 2020

Sleeve Gastrectomy Reduces Blood Pressure in Obese (fa/fa) Zucker Rats

1 reference

12 December 2020

Short-Term Effects of Sleeve Gastrectomy and Caloric Restriction on Blood Pressure in Diet-Induced Obese Rats

1 reference

12 December 2020

Fundus functionality and ghrelin concentrations after bariatric surgery

1 reference

12 December 2020

Serum leptin and ghrelin concentrations of maternal serum, arterial and venous cord blood in healthy and preeclamptic pregnant women

1 reference

12 December 2020

Ghrelin restores the endothelin 1/nitric oxide balance in patients with obesity-related metabolic syndrome

1 reference

12 December 2020

Ghrelin-induced food intake is mediated via the orexin pathway

1 reference

12 December 2020

Leptin induces direct vasodilation through distinct endothelial mechanisms.

1 reference

12 December 2020

Metabolic effects of overnight continuous infusion of unacylated ghrelin in humans

1 reference

12 December 2020

Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure

1 reference

12 December 2020

Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats

1 reference

12 December 2020

Identifiers

DOI

10.1159/000360837

1 reference

22 December 2017

PMCID

5644879

1 reference

22 December 2017

PubMed ID

24685565

1 reference

22 December 2017