aldolase, fructose-bisphosphate B (Q3820163)

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mammalian protein found in Homo sapiens

• ALDOB
• aldolase B, fructose-bisphosphatase
• aldolase 2
• fructose-bisphosphate aldolase B
• liver-type aldolase
• aldolase B, fructose-bisphosphate

edit

Language	Label	Description	Also known as
English	aldolase, fructose-bisphosphate B	mammalian protein found in Homo sapiens	ALDOB aldolase B, fructose-bisphosphatase aldolase 2 fructose-bisphosphate aldolase B liver-type aldolase aldolase B, fructose-bisphosphate

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

18 July 2018

UniProt protein ID

P05062

part of

Fructose-bisphosphate aldolase, class-I

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P05062

TIM barrel

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P05062

Fructose-bisphosphate aldolase class-I active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

1qo52.jpg
1,000 × 797; 303 KB

0 references

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

18 July 2018

UniProt protein ID

P05062

encoded by

ALDOB

1 reference

stated in

UniProt

retrieved

18 July 2018

UniProt protein ID

P05062

molecular function

fructose-1-phosphate aldolase activity

determination method

EXP

IDA

IEA

3 references

retrieved

1 January 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

1 January 2018

stated in

Construction and expression of human aldolase A and B expression plasmids in Escherichia coli host

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

1 January 2018

stated in

Construction and expression of human aldolase A and B expression plasmids in Escherichia coli host

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

EXP

ATPase binding

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

cytoskeletal protein binding

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

fructose binding

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IMP

protein binding

determination method

IPI

2 references

retrieved

9 May 2019

stated in

Novel interaction partners of Bardet-Biedl syndrome proteins

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IPI

retrieved

9 May 2019

stated in

Novel interaction partners of Bardet-Biedl syndrome proteins

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IPI

catalytic activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

lyase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

identical protein binding

determination method

IPI

1 reference

retrieved

9 May 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IPI

fructose-bisphosphate aldolase activity

determination method

IEA

EXP

IDA

7 references

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

1 January 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

1 January 2018

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

1 January 2018

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

1 January 2018

stated in

Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

1 January 2018

stated in

Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

EXP

fructose-bisphosphate aldolase activity

determination method

IDA

IEA

6 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

8 April 2019

stated in

Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

8 April 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

8 April 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

fructose-1-phosphate aldolase activity

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

8 April 2019

stated in

Construction and expression of human aldolase A and B expression plasmids in Escherichia coli host

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

fructose-bisphosphate aldolase activity

determination method

IBA

IDA

IEA

7 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

9 May 2019

stated in

Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

9 May 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IBA

fructose-1-phosphate aldolase activity

determination method

IBA

IDA

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

9 May 2019

stated in

Construction and expression of human aldolase A and B expression plasmids in Escherichia coli host

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IBA

cell component

cytoplasm

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

centriolar satellite

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Novel interaction partners of Bardet-Biedl syndrome proteins

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

microtubule organizing center

determination method

IDA

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

9 May 2019

stated in

Novel interaction partners of Bardet-Biedl syndrome proteins

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

extracellular exosome

determination method

IDA

2 references

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

26 September 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05062&geneProductId=UniProtKB:P05062

determination method

IDA

cytoskeleton

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

cytosol

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

TAS

extracellular exosome

determination method

HDA

1 reference

retrieved

9 May 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

HDA

cytosol

determination method

IBA

TAS

2 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

TAS

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IBA

biological process

gluconeogenesis

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

TAS

positive regulation of ATP-dependent activity

determination method

IGI

1 reference

retrieved

9 May 2019

stated in

Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IGI

glycolytic process

determination method

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

8 April 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

vacuolar proton-transporting V-type ATPase complex assembly

determination method

IGI

1 reference

retrieved

9 May 2019

stated in

Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IGI

canonical glycolysis

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

TAS

fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

TAS

fructose 1,6-bisphosphate metabolic process

determination method

IDA

2 references

retrieved

8 April 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

8 April 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

NADH oxidation

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

fructose metabolic process

determination method

IMP

1 reference

retrieved

9 May 2019

stated in

Catalytic deficiency of human aldolase B in hereditary fructose intolerance caused by a common missense mutation

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IMP

glycolytic process

determination method

IBA

IDA

IEA

4 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P05062

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IEA

retrieved

9 May 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IBA

fructose 1,6-bisphosphate metabolic process

determination method

IBA

IDA

3 references

retrieved

9 May 2019

stated in

Mode of interactions of human aldolase isozymes with cytoskeletons

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

9 May 2019

stated in

Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05062

determination method

IBA

Gene Atlas image

PBB GE ALDOB 211357 s at fs.png
732 × 530; 8 KB

0 references

has part(s)

Fructose-bisphosphate aldolase class-I active site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P05062

Identifiers

RefSeq protein ID

NP_000026

1 reference

stated in

NCBI Gene

retrieved

18 May 2018

Entrez Gene ID

229

UniProt protein ID

P05062

1 reference

stated in

UniProt

retrieved

18 July 2018

UniProt protein ID

P05062

Ensembl protein ID

ENSP00000363988

1 reference

stated in

ensembl Release 93

Ensembl protein ID

ENSP00000363988

ENSP00000481363

1 reference

stated in

ensembl Release 93

Ensembl protein ID

ENSP00000481363

Freebase ID

/m/02pyllc

0 references

Microsoft Academic ID

184054246

0 references

2909835539

0 references

OpenAlex ID

C184054246

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1QO5

1 reference

stated in

UniProt

UniProt protein ID

P05062

retrieved

9 August 2016

language of work or name

English

1XDL

1 reference

stated in

UniProt

UniProt protein ID

P05062

retrieved

9 August 2016

language of work or name

English

1XDM

1 reference

stated in

UniProt

UniProt protein ID

P05062

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(9 entries)

edit

• cawiki Aldolasa B
• cywiki ALDOB
• dewiki Aldolase B
• enwiki Aldolase B
• fawiki آلدولاز B
• frwiki Aldolase B
• jawiki B型アルドラーゼ
• ruwiki Альдолаза B
• ukwiki ALDOB

Wikibooks(0 entries)

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Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

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