SOCS proteins in regulation of receptor tyrosine kinase signaling (Q38202542)

30 August 2017

SOCS proteins in regulation of receptor tyrosine kinase signaling (English)

1 reference

SOCS family protein binding

30 August 2017

1 reference

Gene Ontology release 2020-05-02

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Amilcar Flores-Morales

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Lars Rönnstrand

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

2

Nuzhat N Kabir

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

5 April 2014

1 reference

Cellular and Molecular Life Sciences

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

3297-3310

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705897%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00018-014-1619-y

13 June 2020

exact match

0 references

cites work

Comparative analysis of human and bovine protein kinases reveals unique relationship and functional diversity

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Stem cell factor receptor/c-Kit: from basic science to clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Cloning and characterization of novel CIS family genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Twenty proteins containing a C-terminal SOCS box form five structural classes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

The suppressors of cytokine signalling (SOCS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Socs1 deficiency enhances hepatic insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Extracellular signal-regulated kinase mitogen-activated protein kinase-dependent SOCS-3 gene induction requires c-Jun, signal transducer and activator of transcription 3, and specificity protein 3 transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

The tumor suppressor activity of SOCS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

CSF-1 receptor structure/function in MacCsf1r-/- macrophages: regulation of proliferation, differentiation, and morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS1 controls liver regeneration by regulating HGF signaling in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Activation mechanisms of STAT5 by oncogenic Flt3-ITD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Src-like-adaptor protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Ectopic expression of Flt3 kinase inhibits proliferation and promotes cell death in different human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

The significance of heat shock proteins in breast cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signalling 2 (SOCS-2) expression in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS2 induces neurite outgrowth by regulation of epidermal growth factor receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS-3 is an insulin-induced negative regulator of insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling (SOCS)-3 protein interacts with the insulin-like growth factor-I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Insulin receptor and IRS-1 co-immunoprecipitation with SOCS-3, and IKKα/β phosphorylation are increased in obese Zucker rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Insulin induces suppressor of cytokine signaling-3 tyrosine phosphorylation through janus-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS-1/3 participation in FGF-2 signaling to modulate RANK ligand expression in paget's disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Structure of the SOCS4-ElonginB/C Complex Reveals a Distinct SOCS Box Interface and the Molecular Basis for SOCS-Dependent EGFR Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS6, down-regulated in gastric cancer, inhibits cell proliferation and colony formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Increased SOCS6 stability with PMA requires its N-terminal region and the Erk pathway via Pkcdelta activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Structural Basis for c-KIT Inhibition by the Suppressor of Cytokine Signaling 6 (SOCS6) Ubiquitin Ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Tyrosine-phosphorylated SOCS3 interacts with the Nck and Crk-L adapter proteins and regulates Nck activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signalling gene expression is elevated in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Expression of SOCS-1, suppressor of cytokine signalling-1, in human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Role of SOCS1 in tumor progression and therapeutic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppression of SOCS3 in macrophages prevents cancer metastasis by modifying macrophage phase and MCP2/CCL8 induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Reduced expression of SOCS2 and SOCS6 in hepatocellular carcinoma correlates with aggressive tumor progression and poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Expression of SOCSs in human prostate cancer and their association in prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Constitutive expression of SOCS3 confers resistance to IFN-alpha in chronic myelogenous leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3F136L) cannot regulate erythropoietin responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SOCS2: inhibitor of JAK2V617F-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Epigenetic alterations complement mutation of JAK2 tyrosine kinase in patients with BCR/ABL-negative myeloproliferative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Association of single-nucleotide polymorphisms in the suppressor of cytokine signaling 2 (SOCS2) gene with type 2 diabetes in the Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SB1578, a novel inhibitor of JAK2, FLT3, and c-Fms for the treatment of rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

The analysis of CIS, SOCS1, SOSC2 and SOCS3 transcript levels in peripheral blood mononuclear cells of systemic lupus erythematosus and rheumatoid arthritis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

SYK is a critical regulator of FLT3 in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Suppressor of cytokine signaling (SOCS)-1 is expressed in human prostate cancer and exerts growth-inhibitory function through down-regulation of cyclins and cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1619-Y

Rearrangements involving 12q in myeloproliferative disorders: possible role of HMGA2 and SOCS2 genes

21 January 2018

1 reference

12 December 2020

Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia.

1 reference

12 December 2020

Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis

1 reference

12 December 2020

A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors

1 reference

12 December 2020

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

1 reference

12 December 2020

Differential regulation of signaling pathways for insulin and insulin-like growth factor I

1 reference

12 December 2020

IL-23 selectively promotes the metastasis of colorectal carcinoma cells with impaired Socs3 expression via the STAT5 pathway

1 reference

12 December 2020

Spontaneous resolution of acute gouty arthritis is associated with rapid induction of the anti-inflammatory factors TGFβ1, IL-10 and soluble TNF receptors and the intracellular cytokine negative regulators CIS and SOCS3

1 reference

12 December 2020

Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis

1 reference

12 December 2020

SOCS2 negatively regulates growth hormone action in vitro and in vivo

1 reference

12 December 2020

Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome

1 reference

12 December 2020

Epidermal growth factor-induced apoptosis in A431 cells can be reversed by reducing the tyrosine kinase activity

1 reference

12 December 2020

Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma

1 reference

12 December 2020

Observations on the effects of Suppressor of Cytokine Signaling 7 (SOCS7) knockdown in breast cancer cells: their in vitro response to Insulin Like Growth Factor I (IGF-I)

1 reference

12 December 2020

Grb10 is a dual regulator of receptor tyrosine kinase signaling

1 reference

12 December 2020