Brown adipose tissue and its therapeutic potential. (Q38203348)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Brown adipose tissue and its therapeutic potential (English)

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13 March 2020

2

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13 March 2020

author name string

M E Lidell

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

S Enerbäck

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

language of work or name

English

0 references

publication date

28 April 2014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

Journal of Internal Medicine

13 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

276

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

364-377

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24717051%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Unexpected evidence for active brown adipose tissue in adult humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Functional brown adipose tissue in healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Identification and importance of brown adipose tissue in adult humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Cold-activated brown adipose tissue in healthy men

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

A critical appraisal of the prevalence and metabolic significance of brown adipose tissue in adult humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Cidea-deficient mice have lean phenotype and are resistant to obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Impact of age on the relationships of brown adipose tissue with sex and adiposity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown adipose tissue: function and physiological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Mechanism of fatty-acid-dependent UCP1 uncoupling in brown fat mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

The mitochondrial uncoupling-protein homologues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown adipose tissue and seasonal variation in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Presence of brown adipocytes in retroperitoneal fat from patients with benign adrenal tumors: relationship with outdoor temperature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

PRDM16 controls a brown fat/skeletal muscle switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Human BAT possesses molecular signatures that resemble beige/brite cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Evidence for two types of brown adipose tissue in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Transcriptional control of brown fat determination by PRDM16

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Development of insulin resistance in mice lacking PGC-1α in adipose tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

RIP140-targeted repression of gene expression in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Nuclear receptor corepressor RIP140 regulates fat accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

A role for brown adipose tissue in diet-induced thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown adipose tissue activity controls triglyceride clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Cold exposure induces tissue-specific modulation of the insulin-signalling pathway in Rattus norvegicus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown adipose tissue in humans is activated by elevated plasma catecholamines levels and is inversely related to central obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Adrenergic activation of triiodothyronine production in brown adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

T3-mediated expression of PGC-1alpha via a far upstream located thyroid hormone response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Hyperthyroidism increases brown fat metabolism in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

TGR5-mediated bile acid sensing controls glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Thermogenic activation induces FGF21 expression and release in brown adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Evidence against a beneficial effect of irisin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Mitochondrial uncoupling as a target for drug development for the treatment of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Acute effect of L-796568, a novel beta 3-adrenergic receptor agonist, on energy expenditure in obese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Brown adipose tissue in morbidly obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Effect of nicotine and ephedrine on the accumulation of 18F-FDG in brown adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Bile acid binding resin improves metabolic control through the induction of energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

A TRbeta-selective agonist confers resistance to diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Recruited brown adipose tissue as an antiobesity agent in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

Non-shivering Thermogenesis and Brown Adipose Tissue in the Human New-born Infant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255

21 January 2018

Neither brown nor white

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12255