Connexins in colorectal cancer pathogenesis (Q38206124)

31 August 2017

Connexins in colorectal cancer pathogenesis (English)

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31 August 2017

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5

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31 May 2020

Matthias Kolberg

8

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31 May 2020

author name string

Solveig Sirnes

1

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31 May 2020

Guro E Lind

2

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31 May 2020

Jarle Bruun

3

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31 May 2020

Tone A Fykerud

4

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31 May 2020

Edgar Rivedal

7

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31 May 2020

Edward Leithe

9

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31 May 2020

Ragnhild A Lothe

6

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31 May 2020

language of work or name

English

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publication date

5 May 2014

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International Journal of Cancer

31 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24752574%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

137

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31 May 2020

issue

1

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31 May 2020

page(s)

1-11

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Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

31 May 2020

cites work

1 reference

Modifiable risk factors for cancer

21 January 2018

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Genetic alterations during colorectal-tumor development

21 January 2018

1 reference

The intestinal crypt, a prototype stem cell compartment

21 January 2018

1 reference

Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers

21 January 2018

1 reference

The chromosomal instability pathway in colon cancer

21 January 2018

1 reference

Microsatellite instability in colorectal cancer

21 January 2018

1 reference

Plasma membrane channels formed by connexins: their regulation and functions.

21 January 2018

1 reference

Life cycle of connexins in health and disease

21 January 2018

1 reference

Molecular connexin partner remodeling orchestrates connexin traffic: from physiology to pathophysiology.

21 January 2018

1 reference

Regulation of gap junction intercellular communication by the ubiquitin system

21 January 2018

1 reference

Managing the complexity of communication: regulation of gap junctions by post-translational modification

21 January 2018

1 reference

Connexin43 phosphorylation: structural changes and biological effects

21 January 2018

1 reference

Intercellular Communication and the Control of Tissue Growth: Lack of Communication between Cancer Cells

21 January 2018

1 reference

Defective gap junctional intercellular communication in the carcinogenic process

21 January 2018

1 reference

Epidermal growth factor stimulates the disruption of gap junctional communication and connexin43 phosphorylation independent of 12-0-tetradecanoylphorbol 13-acetate-sensitive protein kinase C: the possible involvement of mitogen-activated protein ki

21 January 2018

1 reference

Analyzing phorbol ester effects on gap junctional communication: a dramatic inhibition of assembly

21 January 2018

1 reference

Tumor promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells

21 January 2018

1 reference

Elimination of Metabolic Cooperation in Chinese Hamster Cells by a Tumor Promoter

21 January 2018

1 reference

Involvement of gap junctions in tumorigenesis: transfection of tumor cells with connexin 32 cDNA retards growth in vivo

21 January 2018

1 reference

Inducible expression of the gap junction protein connexin43 decreases the neoplastic potential of HT-1080 human fibrosarcoma cells in vitro and in vivo

21 January 2018

1 reference

Connexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis

21 January 2018

1 reference

Cx31.1 acts as a tumour suppressor in non-small cell lung cancer (NSCLC) cell lines through inhibition of cell proliferation and metastasis

21 January 2018

1 reference

Growth retardation in glioma cells cocultured with cells overexpressing a gap junction protein

21 January 2018

1 reference

Down-regulation of Cx43 by retroviral delivery of small interfering RNA promotes an aggressive breast cancer cell phenotype

21 January 2018

1 reference

Increased susceptibility to urethane-induced lung tumors in mice with decreased expression of connexin43.

21 January 2018

1 reference

Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver

21 January 2018

1 reference

Mice deficient for the gap junction protein Connexin32 exhibit increased radiation-induced tumorigenesis associated with elevated mitogen-activated protein kinase (p44/Erk1, p42/Erk2) activation.

21 January 2018

1 reference

High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32.

21 January 2018

1 reference

Gap junctions and connexins as therapeutic targets in cancer

21 January 2018

1 reference

Connexins as targets for cancer chemoprevention and chemotherapy

21 January 2018

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Implications and challenges of connexin connections to cancer.

21 January 2018

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Connexins as precocious markers and molecular targets for chemical and pharmacological agents in carcinogenesis

21 January 2018

1 reference

Enhanced apoptosis under low serum conditions in human glioblastoma cells by connexin 43 (Cx43).

21 January 2018

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Connexins and apoptotic transformation

21 January 2018

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Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome

21 January 2018

1 reference

Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis

21 January 2018

1 reference

Connexin 26 gene therapy of human bladder cancer: induction of growth suppression, apoptosis, and synergy with Cisplatin

21 January 2018

1 reference

Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication

21 January 2018

1 reference

Increased gap junctional intercellular communication is directly related to the anti-tumor effect of all-trans-retinoic acid plus tamoxifen in a human mammary cancer cell line

21 January 2018

1 reference

Connexins and their channels in cell growth and cell death

21 January 2018

1 reference

Connexins and cell signaling in development and disease

21 January 2018

1 reference

The gap junction-independent tumor-suppressing effect of connexin 43

21 January 2018

1 reference

Dual functions for connexins: Cx43 regulates growth independently of gap junction formation

21 January 2018

1 reference

Differential effect of subcellular localization of communication impairing gap junction protein connexin43 on tumor cell growth in vivo

21 January 2018

1 reference

Paracrine signaling through plasma membrane hemichannels

21 January 2018

1 reference

The gap junction proteome and its relationship to disease

21 January 2018

1 reference

The role of connexins in controlling cell growth and gene expression

21 January 2018

1 reference

Connexin43 repression following epithelium-to-mesenchyme transition in embryonal carcinoma cells requires Snail1 transcription factor.

21 January 2018

1 reference

Transfection with different connexin genes alters growth and differentiation of human choriocarcinoma cells

21 January 2018

1 reference

Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture

21 January 2018

1 reference

Role for connexin 26 in metastasis of human malignant melanoma: communication between melanoma and endothelial cells via connexin 26.

21 January 2018

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Role of connexins in metastatic breast cancer and melanoma brain colonization

21 January 2018

1 reference

Cytoplasmic dye transfer between metastatic tumor cells and vascular endothelium

21 January 2018

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A role for heterologous gap junctions between melanoma and endothelial cells in metastasis

21 January 2018

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Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells

21 January 2018

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Gap junctions and cancer: new functions for an old story

21 January 2018

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Increased expression of connexins 26 and 43 in lymph node metastases of breast cancer

21 January 2018

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Increased invasive capacity of connexin43-overexpressing malignant glioma cells

21 January 2018

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Aberrant expression of connexin 26 is associated with lung metastasis of colorectal cancer.

21 January 2018

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Alterations in connexin26 expression during colorectal carcinogenesis.

21 January 2018

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Altered expression pattern of molecular factors involved in colonic smooth muscle functions: an immunohistochemical study in patients with diverticular disease.

21 January 2018

1 reference

DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer

21 January 2018

1 reference

Expressions of connexin and par-3 in the distal margin of rectal cancer after ultra-low anterior resection.

21 January 2018

1 reference

Clinical significance of the expression of connexin26 in colorectal cancer

21 January 2018

1 reference

Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells

21 January 2018

1 reference

Lack of bystander killing in herpes simplex virus thymidine kinase-transduced colon cell lines due to deficient connexin43 gap junction formation

21 January 2018

1 reference

Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors.

21 January 2018

1 reference

Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning.

21 January 2018

1 reference

Genes upregulated in a metastasizing human colon carcinoma cell line.

21 January 2018

1 reference

Wnt/β-catenin signaling and disease

21 January 2018

1 reference

Homotypic gap junctional communication associated with metastasis suppression increases with PKA activity and is unaffected by PI3K inhibition

21 January 2018

1 reference

Anti-breast cancer agents, quinolines, targeting gap junction

21 January 2018

1 reference

Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication

21 January 2018

1 reference

Chemopreventive actions of polyphenolic compounds in cancer

21 January 2018

1 reference

Augmentation of differentiation and gap junction function by kaempferol in partially differentiated colon cancer cells.

21 January 2018

1 reference

Gamma linolenic acid regulates gap junction communication in endothelial cells and their interaction with tumour cells

21 January 2018

1 reference

Selenium and colorectal adenomas risk: a meta-analysis

21 January 2018

1 reference

Selenium and colon cancer--from chemoprevention to new treatment modality

21 January 2018

1 reference

Selenomethionine induces sustained ERK phosphorylation leading to cell-cycle arrest in human colon cancer cells.

21 January 2018

1 reference

Profiling of selenomethionine responsive genes in colon cancer by microarray analysis

21 January 2018

1 reference

In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

21 January 2018

1 reference

Purified herpes simplex thymidine kinase retroviral particles. II. Influence of clinical parameters and bystander killing mechanisms

21 January 2018

1 reference

Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins

21 January 2018

1 reference

Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells

21 January 2018

1 reference

Protein and messenger RNA expression of connexin43 in astrocytomas: implications in brain tumor gene therapy

21 January 2018

1 reference

Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase

21 January 2018

1 reference

Correlation between connexin 26 expression and poor prognosis of esophageal squamous cell carcinoma.

21 January 2018

1 reference

Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer

21 January 2018

1 reference

Lack of evidence for low-LET radiation induced bystander response in normal human fibroblasts and colon carcinoma cells

21 January 2018

1 reference

Connexin-independent ganciclovir-mediated killing conferred on bystander effect-resistant cell lines by a herpes simplex virus-thymidine kinase-expressing colon cell line

21 January 2018

1 reference

Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart

21 January 2018

1 reference

Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43.

21 January 2018

1 reference

The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation

21 January 2018

1 reference

Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-acetate treatment

21 January 2018

1 reference

Epidermal growth factor disrupts gap-junctional communication and induces phosphorylation of connexin43 on serine

21 January 2018

1 reference

Epidermal growth factor regulates ubiquitination, internalization and proteasome-dependent degradation of connexin43.

21 January 2018

1 reference

TGF-beta1 down-regulates connexin 43 expression and gap junction intercellular communication in rat hepatic stellate cells

21 January 2018

1 reference