Fatty kidney: emerging role of ectopic lipid in obesity-related renal disease (Q38209300)

31 August 2017

Fatty kidney: emerging role of ectopic lipid in obesity-related renal disease (English)

1 reference

31 August 2017

1 reference

2

Piero Ruggenenti

1 reference

31 August 2017

14

Esteban Porrini

2 references

ORCID Public Data File 2021

31 August 2017

1

Aiko P J de Vries

1 reference

31 August 2017

Xiong Z Ruan

3

1 reference

31 August 2017

Manuel Praga

4

1 reference

31 August 2017

Josep M Cruzado

5

1 reference

31 August 2017

Ingeborg M Bajema

6

1 reference

31 August 2017

Vivette D D'Agati

7

1 reference

31 August 2017

Hildo J Lamb

8

1 reference

31 August 2017

Drazenka Pongrac Barlovic

9

1 reference

31 August 2017

Radovan Hojs

10

1 reference

31 August 2017

Manuela Abbate

11

1 reference

31 August 2017

Rosa Rodriquez

12

1 reference

31 August 2017

Carl Erik Mogensen

13

1 reference

31 August 2017

ERA-EDTA Working Group Diabesity

15

1 reference

31 August 2017

1 May 2014

1 reference

The Lancet: Diabetes & Endocrinology

31 August 2017

1 reference

31 August 2017

2

1 reference

31 August 2017

417-426

1 reference

31 August 2017

5

1 reference

Evolving importance of kidney disease: from subspecialty to global health burden

31 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Metabolic syndrome--a new world-wide definition. A Consensus Statement from the International Diabetes Federation

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Metabolic syndrome and kidney disease: a systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The distinction of metabolically 'healthy' from 'unhealthy' obese individuals

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Central body fat distribution associates with unfavorable renal hemodynamics independent of body mass index

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Waist-to-hip ratio, body mass index, and subsequent kidney disease and death.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Banting lecture 1988. Role of insulin resistance in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Body mass index and risk for end-stage renal disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians?

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Waist circumference as a measure for indicating need for weight management.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Prehypertension, obesity, and risk of kidney disease: 20-year follow-up of the HUNT I study in Norway

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Adverse renal consequences of obesity

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Excessive body weight as a new independent risk factor for clinical and pathological progression in primary IgA nephritis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Influence of obesity on the appearance of proteinuria and renal insufficiency after unilateral nephrectomy

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Fasting insulin modifies the relation between age and renal function.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Glomerular hyperfiltration: a new marker of metabolic risk.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Glomerular hyperfiltration: definitions, mechanisms and clinical implications.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Body mass index and body fat distribution as renal risk factors: a focus on the role of renal haemodynamics

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Insulin's acute effects on glomerular filtration rate correlate with insulin sensitivity whereas insulin's acute effects on proximal tubular sodium reabsorption correlation with salt sensitivity in normal subjects.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The role of the renin-angiotensin-aldosterone system in obesity-related renal diseases

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Hemodynamically mediated glomerular injury and the progressive nature of kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Glomerular hyperfiltration and renal disease progression in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Podocyte lesions in patients with obesity-related glomerulopathy.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Obesity-associated focal segmental glomerulosclerosis: pathological features of the lesion and relationship with cardiomegaly and hyperlipidemia

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Pathological influence of obesity on renal structural changes in chronic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Renal injury in the extremely obese patients with normal renal function.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Absence of glomerular injury or nephron loss in a normotensive rat remnant kidney model

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Focal segmental glomerulosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

An update on the lipid nephrotoxicity hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Lipid homeostasis, lipotoxicity and the metabolic syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

"Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Adipophilin/perilipin-2 as a lipid droplet-specific marker for metabolically active cells and diseases associated with metabolic dysregulation

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Leukocyte lipid bodies - Biogenesis and functions in inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Macrophage differentiation to foam cells

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Lipotoxic diseases of nonadipose tissues in obesity

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Disordered lipid metabolism and the pathogenesis of insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Ectopic fat storage in heart, blood vessels and kidneys in the pathogenesis of cardiovascular diseases

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Extrahepatic complications of nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Lipid redistribution in renal dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Remarks on the Fatty Transformation of the Kidney.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The mesangial cell revisited: no cell is an island

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Human mesangial cells express inducible macrophage scavenger receptor

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Apolipoproteins and lipoprotein receptors in glomeruli in human kidney diseases

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Very-low-density lipoprotein-induced triglyceride accumulation in human mesangial cells is mainly mediated by lipoprotein lipase.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Inflammatory cytokines disrupt LDL-receptor feedback regulation and cause statin resistance: a comparative study in human hepatic cells and mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

IGF-1-induced lipid accumulation impairs mesangial cell migration and contractile function.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Podocyte injury damages other podocytes

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Glomerular epithelial stem cells: the good, the bad, and the ugly.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Growth-dependent podocyte failure causes glomerulosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Mammalian target of rapamycin and the kidney. I. The signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

mTOR signaling in growth control and disease

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The insulin receptor and the kidney.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Insulin signaling to the glomerular podocyte is critical for normal kidney function

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Interleukin-1β enhances the intracellular accumulation of cholesterol by up-regulating the expression of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase in podocytes

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Receptor-mediated lipoprotein uptake by human glomerular cells: comparison with skin fibroblasts and HepG2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Substrate-utilization of the Human Kidney

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Clinical significance of urinary liver-type fatty acid-binding protein in patients with diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Fatty acids exacerbate tubulointerstitial injury in protein-overload proteinuria

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Glucose control by the kidney: an emerging target in diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Liver and kidney metabolism during prolonged starvation

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Deletion of the insulin receptor in the proximal tubule promotes hyperglycemia

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The nephrotic syndrome: a complication of massive obesity

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Absence of hypoalbuminemia despite massive proteinuria in focal segmental glomerulosclerosis secondary to hyperfiltration

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Nephrectomy elicits impact of age and BMI on renal hemodynamics: lower postdonation reserve capacity in older or overweight kidney donors

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Glomerular volume and renal histology in obese and non-obese living kidney donors

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The GFR and GFR decline cannot be accurately estimated in type 2 diabetics

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Metabolic imaging of human kidney triglyceride content: reproducibility of proton magnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Renal lipid metabolism and lipotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Renal lipids and oxygenation in diabetic mice: noninvasive quantification with MR imaging

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The failing heart--an engine out of fuel

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Weight loss interventions in chronic kidney disease: a systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

ACE inhibition is renoprotective among obese patients with proteinuria

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

1 reference

https://api.crossref.org/works/10.1016%2FS2213-8587%2814%2970065-8

7 January 2021

10.1016/S2213-8587(14)70065-8

Identifiers

DOI

1 reference

31 August 2017

1 reference