Anticancer activities of essential oils constituents and synergy with conventional therapies: a review (Q38211993)

31 August 2017

title

Anticancer activities of essential oils constituents and synergy with conventional therapies: a review (English)

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31 August 2017

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Jean-François Lesgards

1

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31 August 2017

Nicolas Baldovini

2

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31 August 2017

Nicolas Vidal

3

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31 August 2017

Sylvia Pietri

4

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31 August 2017

publication date

16 May 2014

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31 August 2017

published in

Phytotherapy Research

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31 August 2017

volume

28

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31 August 2017

issue

10

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31 August 2017

page(s)

1423-1446

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The effect of route of administration in thymoquinone toxicity in male and female rats

31 August 2017

cites work

1 reference

Helichrysum gymnocephalum essential oil: chemical composition and cytotoxic, antimalarial and antioxidant activities, attribution of the activity origin by correlations

21 January 2018

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Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways

21 January 2018

1 reference

Anti-tumor properties of blackseed (Nigella sativa L.) extracts

21 January 2018

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Mammary carcinomas induced in human c-Ha-ras proto-oncogene transgenic rats are estrogen-independent, but responsive to d-limonene treatment

21 January 2018

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Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo

21 January 2018

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Metabolism in rats of p-cymene derivatives: carvacrol and thymol

21 January 2018

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The effect of terpenoid compounds on cytochrome P-450 levels in rat liver

21 January 2018

1 reference

Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay

21 January 2018

1 reference

Biological effects of essential oils--a review

21 January 2018

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Toxicity prediction of compounds from turmeric (Curcuma longa L)

21 January 2018

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Fragrance material review on alpha-bisabolol

21 January 2018

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The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation

21 January 2018

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Tumor protein 53-induced nuclear protein 1 is a major mediator of p53 antioxidant function

21 January 2018

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Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts

21 January 2018

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Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells.

21 January 2018

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alpha-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cells

21 January 2018

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Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells

21 January 2018

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Involvement of mitochondrial permeability transition pore opening in alpha-bisabolol induced apoptosis.

21 January 2018

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Essential oil of Artemisia capillaris induces apoptosis in KB cells via mitochondrial stress and caspase activation mediated by MAPK-stimulated signaling pathway

21 January 2018

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Effectiveness of combined limonene and 4-hydroxyandrostenedione in the treatment of NMU-induced rat mammary tumours

21 January 2018

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Effect of thymol on Ca2+ homeostasis and viability in MG63 human osteosarcoma cells

21 January 2018

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Pharmacokinetics and tissue distribution of the sesquiterpene alpha-humulene in mice.

21 January 2018

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alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.

21 January 2018

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Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells

21 January 2018

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In vivo effect of alpha-bisabolol, a nontoxic sesquiterpene alcohol, on the induction of spontaneous mammary tumors in HER-2/neu transgenic mice

21 January 2018

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Antitumor activity of (-)-alpha-bisabolol-based thiosemicarbazones against human tumor cell lines

21 January 2018

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Insight into the apoptosis-inducing action of alpha-bisabolol towards malignant tumor cells: involvement of lipid rafts and Bid.

21 January 2018

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Antineoplastic and apoptotic potential of traditional medicines thymoquinone and diosgenin in squamous cell carcinoma

21 January 2018

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Melissa officinalis L. essential oil: antitumoral and antioxidant activities

21 January 2018

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Constituents of aromatic plants: carvacrol

21 January 2018

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Effect of thymol on peripheral blood mononuclear cell PBMC and acute promyelotic cancer cell line HL-60.

21 January 2018

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Omega-hydroxylation of farnesol by mammalian cytochromes p450.

21 January 2018

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

21 January 2018

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Geraniol and beta-ionone inhibit proliferation, cell cycle progression, and cyclin-dependent kinase 2 activity in MCF-7 breast cancer cells independent of effects on HMG-CoA reductase activity

21 January 2018

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Anti-cancer properties of Nigella spp. essential oils and their major constituents, thymoquinone and beta-elemene.

21 January 2018

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Combinatorial effects of thymoquinone on the anti-cancer activity of doxorubicin

21 January 2018

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Oregano: chemical analysis and evaluation of its antimalarial, antioxidant, and cytotoxic activities.

21 January 2018

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Effects of anticarcinogenic monoterpenes on phase II hepatic metabolizing enzymes

21 January 2018

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Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells

21 January 2018

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Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity

21 January 2018

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Chemotherapy-induced weakness and fatigue in skeletal muscle: the role of oxidative stress

21 January 2018

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Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1.

21 January 2018

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Cancer chemoprevention and therapy by monoterpenes

21 January 2018

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Pharmacological studies with compounds of chamomile. IV. Studies on toxicity of (-)-alpha-bisabolol (author's transl)

21 January 2018

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Inhibition of Murine Subcutaneous and Intravenous Benzo(rst)pentaphene Carcinogenesis by Sweet Orange Oils and d-Limonene

21 January 2018

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Effect of thymol on Ca2+ homeostasis and viability in human glioblastoma cells

21 January 2018

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Concurrent sulforaphane and eugenol induces differential effects on human cervical cancer cells

21 January 2018

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Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells

21 January 2018

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Genotoxicity and antigenotoxicity of some essential oils evaluated by wing spot test of Drosophila melanogaster

21 January 2018

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Terpenoid biotransformation in mammals. V. Metabolism of (+)-citronellal, (+-)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminaldehyde, thujone, and (+-)-carvone in rabbits

21 January 2018

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Apoptotic effect of eugenol in human colon cancer cell lines.

21 January 2018

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Percutaneous absorption of the montoterperne carvone: implication of stereoselective metabolism on blood levels

21 January 2018

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Food flavourings and compounds of related structure I. Acute oral toxicity

21 January 2018

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Induction of apoptosis by d-limonene is mediated by a caspase-dependent mitochondrial death pathway in human leukemia cells

21 January 2018

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Effect of thymoquinone on 1,2-dimethyl-hydrazine-induced oxidative stress during initiation and promotion of colon carcinogenesis

21 January 2018

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Eugenol--from the remote Maluku Islands to the international market place: a review of a remarkable and versatile molecule.

21 January 2018

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Review of kidney sections from a subchronic d-limonene oral dosing study conducted by the National Cancer Institute

21 January 2018

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In vitro toxicological properties of thymoquinone

21 January 2018

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Geraniol inhibits prostate cancer growth by targeting cell cycle and apoptosis pathways.

21 January 2018

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Safety evaluation and risk assessment of d-Limonene

21 January 2018

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Studies on the metabolism of d-limonene (p-mentha-1,8-diene). IV. Isolation and characterization of new metabolites and species differences in metabolism

21 January 2018

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Cytotoxic and antioxidative sesquiterpenoids from Heterotheca inuloides

21 January 2018

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Emerging avenues linking inflammation and cancer

21 January 2018

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5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress.

21 January 2018

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Fragrance material review on nerolidol (isomer unspecified).

21 January 2018

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Fragrance material review on geraniol

21 January 2018

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Fragrance material review on farnesol

21 January 2018

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Potentiating effect of beta-caryophyllene on anticancer activity of alpha-humulene, isocaryophyllene and paclitaxel

21 January 2018

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Assessment of lifestyle effects on the overall antioxidant capacity of healthy subjects

21 January 2018

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Effect of reactive oxygen and carbonyl species on crucial cellular antioxidant enzymes

21 January 2018

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Down-regulation of survivin and hypoxia-inducible factor-1 α by β-elemene enhances the radiosensitivity of lung adenocarcinoma xenograft

21 January 2018

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β-Elemene radiosensitizes lung cancer A549 cells by enhancing DNA damage and inhibiting DNA repair

21 January 2018

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Antineoplastic effect of beta-elemene on prostate cancer cells and other types of solid tumour cells

21 January 2018

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beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis

21 January 2018

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Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase

21 January 2018

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HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis

21 January 2018

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Carvacrol-induced [Ca2+]i rise and apoptosis in human glioblastoma cells

21 January 2018

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β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis

21 January 2018

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Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae--a review

21 January 2018

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Inhibition of growth and metastasis of human gastric cancer implanted in nude mice by d-limonene

21 January 2018

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AMPK as a metabolic tumor suppressor: control of metabolism and cell growth

21 January 2018

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Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG.

21 January 2018

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Eugenol inhibits cell proliferation via NF-κB suppression in a rat model of gastric carcinogenesis induced by MNNG.

21 January 2018

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Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines

21 January 2018

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Limonene exerts antiproliferative effects and increases nitric oxide levels on a lymphoma cell line by dual mechanism of the ERK pathway: relationship with oxidative stress.

21 January 2018

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Toxicity against gastric cancer cells by combined treatment with 5-fluorouracil and mitomycin c: implication in oxidative stress

21 January 2018

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Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells

21 January 2018

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Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol

21 January 2018

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Investigation of the mutagenic and antimutagenic effects of Origanum compactum essential oil and some of its constituents

21 January 2018

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Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer

21 January 2018

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A comparative in vitro kinetic study of [14C]-eugenol and [14C]-methyleugenol activation and detoxification in human, mouse, and rat liver and lung fractions

21 January 2018

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Sesquiterpenes: natural products that decrease cancer growth

21 January 2018

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Absence of tumor suppressor tumor protein 53-induced nuclear protein 1 (TP53INP1) sensitizes mouse thymocytes and embryonic fibroblasts to redox-driven apoptosis

21 January 2018

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The interplay between inflammation and oxidative stress in carcinogenesis

21 January 2018

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Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase

21 January 2018

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Eugenol restricts DMBA croton oil induced skin carcinogenesis in mice: downregulation of c-Myc and H-ras, and activation of p53 dependent apoptotic pathway

21 January 2018

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β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

21 January 2018

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Cardioprotective and anti-oxidant effects of the terpenoid constituents of Ginkgo biloba extract (EGb 761).

21 January 2018

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Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line

21 January 2018

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d -Limonene sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis

21 January 2018

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Anticancer activity of Nigella sativa (black seed) - a review

21 January 2018

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Ginkgo biloba extract EGb 761 attenuates myocardial stunning in the pig heart

21 January 2018

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Pre-radiotherapy plasma carotenoids and markers of oxidative stress are associated with survival in head and neck squamous cell carcinoma patients: a prospective study

21 January 2018

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Inhibitory effects of Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis in mice

21 January 2018

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Effects of thymol on B16-F10 melanoma cells

21 January 2018

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Organ accumulation in mice after inhalation of single or mixed essential oil compounds

21 January 2018

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Antitumor effects of α-bisabolol against pancreatic cancer

21 January 2018

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Anticancer activity of an essential oil from Cymbopogon flexuosus

21 January 2018

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Selective cytotoxicity of Aniba rosaeodora essential oil towards epidermoid cancer cells through induction of apoptosis

21 January 2018

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Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.

21 January 2018

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Composition and cytotoxic activity of the leaf essential oil of Comptonia peregrina (L.) Coulter

21 January 2018

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Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays

21 January 2018

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Inhibition by D-limonene of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.

21 January 2018

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Role of oxygen radicals in DNA damage and cancer incidence.

21 January 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

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Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis

21 January 2018

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Chemopreventive efficacy of geraniol against 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.

21 January 2018

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On the Origin of Cancer Cells

21 January 2018

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Assessment of the subchronic oral toxicity of d-limonene in dogs

21 January 2018

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d-limonene mechanistic data and risk assessment: absolute species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion

21 January 2018

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Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.

21 January 2018

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Reversion of multidrug resistance in a chemoresistant human breast cancer cell line by β-elemene

21 January 2018

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Eugenol isolated from the essential oil of Eugenia caryophyllata induces a reactive oxygen species-mediated apoptosis in HL-60 human promyelocytic leukemia cells

21 January 2018

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Β-elemene inhibits Hsp90/Raf-1 molecular complex inducing apoptosis of glioblastoma cells

21 January 2018

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Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis

21 January 2018

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Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PTR.5165

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31 August 2017

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