Caspase-2: the reinvented enzyme (Q38216592)

31 August 2017

title

Caspase-2: the reinvented enzyme (English)

1 reference

31 August 2017

M Olsson

1

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Boris Zhivotovsky

object named as

B Zhivotovsky

series ordinal

3

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author name string

J Forsberg

series ordinal

2

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31 August 2017

language of work or name

English

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publication date

2 June 2014

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31 August 2017

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31 August 2017

volume

34

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31 August 2017

issue

15

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31 August 2017

page(s)

1877-1882

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

31 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Characterization of cytoplasmic caspase-2 activation by induced proximity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 activation in the absence of PIDDosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Defects in regulation of apoptosis in caspase-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

A tumor suppressor function for caspase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

PIDDosome-independent tumor suppression by Caspase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Tumor-suppressing function of caspase-2 requires catalytic site Cys-320 and site Ser-139 in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 deficiency enhances aging-related traits in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

miR-708 promotes the development of bladder carcinoma via direct repression of Caspase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Metabolic regulation of CaMKII protein and caspases in Xenopus laevis egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Chromosomal instability determines taxane response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

21 January 2018

Aneuploidy and cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase 2 is both required for p53-mediated apoptosis and downregulated by p53 in a p21-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 is activated at the CD95 death-inducing signaling complex in the course of CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Cyclin D3 action in androgen receptor regulation and prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2-Based Regulation of the Androgen Receptor and Cell Cycle in the Prostate Cancer Cell Line LNCaP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Death through a tragedy: mitotic catastrophe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

DNA damage induces two distinct modes of cell death in ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Targeting checkpoint kinase 1 in cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 is required for cell death induced by cytoskeletal disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 function in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Coenzyme Q10 rescues ethanol-induced corneal fibroblast apoptosis through the inhibition of caspase-2 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Metabolic profiling of cell growth and death in cancer: applications in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Caspase-2 is essential for c-Jun transcriptional activation and Bim induction in neuron death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

Role of ATM in oxidative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdCl2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

ATM kinase activity modulates ITCH E3-ubiquitin ligase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

21 January 2018

PIDD: A Switch Hitter

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.139

31 March 2020

Identifiers

DOI

10.1038/ONC.2014.139

1 reference

Dimensions Publication ID

31 August 2017

1029468956

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1 reference