Osteopontin as a therapeutic target for cancer (Q38217758)

31 August 2017

Osteopontin as a therapeutic target for cancer (English)

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31 August 2017

Gaurab Roy

12

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Santosh Kumar

object named as

Santosh Kumar

10

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Dhiraj Kumar

object named as

Dhiraj Kumar

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Gopal Kundu

22

object named as

Gopal C Kundu

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31 August 2017

Monalisa Bandopadhyay

1

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31 August 2017

Anuradha Bulbule

2

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31 August 2017

Ramesh Butti

3

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31 August 2017

Goutam Chakraborty

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31 August 2017

Priyanka Ghorpade

5

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31 August 2017

Pompom Ghosh

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31 August 2017

Mahadeo Gorain

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31 August 2017

Smita Kale

8

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31 August 2017

Kumar V S Totakura

11

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31 August 2017

Priyanka Sharma

13

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31 August 2017

Dattatrya Shetti

14

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31 August 2017

Gowrishankar Soundararajan

15

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31 August 2017

Dhanashri Thorat

16

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31 August 2017

Deepti Tomar

17

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31 August 2017

Radha Nalukurthi

18

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31 August 2017

Remya Raja

19

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31 August 2017

Rosalin Mishra

20

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31 August 2017

Amit S Yadav

21

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31 August 2017

language of work or name

English

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publication date

4 June 2014

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Expert Opinion on Therapeutic Targets

31 August 2017

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31 August 2017

18

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31 August 2017

8

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31 August 2017

883-895

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Hallmarks of Cancer: The Next Generation

31 August 2017

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https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Migratory neighbors and distant invaders: tumor-associated niche cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin: role in cell signaling and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

The multifaceted roles of osteopontin in cell signaling, tumor progression and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin: role in immune regulation and stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin is a marker for cancer aggressiveness and patient survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Hypoxia-driven osteopontin contributes to breast tumor growth through modulation of HIF1α-mediated VEGF-dependent angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Senescent stromal-derived osteopontin promotes preneoplastic cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Functional characterization of stromal osteopontin in melanoma progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin stimulates tumor growth and activation of promatrix metalloproteinase-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha /IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaB-mediated promatrix metalloproteinase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin is produced by mast cells and affects IgE-mediated degranulation and migration of mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Chemokine (C-C motif) ligand 20, a potential biomarker for Graves' disease, is regulated by osteopontin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin-deficiency suppresses growth of B16 melanoma cells implanted in bone and osteoclastogenesis in co-cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Deletion of the thrombin cleavage domain of osteopontin mediates breast cancer cell adhesion, proteolytic activity, tumorgenicity, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

An osteopontin splice variant induces anchorage independence in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin-c is a selective marker of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta through the NF-kappaB and MAPK pathways in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Abrogation of the interaction between osteopontin and alphavbeta3 integrin reduces tumor growth of human lung cancer cells in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin is associated with decreased apoptosis and αv integrin expression in lung adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Integrative analyses identify osteopontin, LAMB3 and ITGB1 as critical pro-metastatic genes for lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

p38 kinase is crucial for osteopontin-induced furin expression that supports cervical cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin: an emerging therapeutic target for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin induces beta-catenin signaling through activation of Akt in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin expression correlates with nuclear factor-κB activation and apoptosis downregulation in clear cell renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin increases breast cancer cell sensitivity to specific signaling pathway inhibitors in preclinical models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Fibronectin supports TNF-alpha-induced osteopontin expression through beta1 integrin and ERK in HN-22 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin-c splicing isoform contributes to ovarian cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Hypoxic gene expression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Microenvironmental regulation of tumor progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Tiam1-regulated osteopontin in senescent fibroblasts contributes to the migration and invasion of associated epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin stimulates preneoplastic cellular proliferation through activation of the MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin up-regulates critical epithelial-mesenchymal transition transcription factors to induce an aggressive breast cancer phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Mesenchymal stem cells require integrin β1 for directed migration induced by osteopontin in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin promotes mesenchymal stem cell migration and lessens cell stiffness via integrin β1, FAK, and ERK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Human mesenchymal stem cell and epithelial hepatic carcinoma cell lines in admixture: concurrent stimulation of cancer-associated fibroblasts and epithelial-to-mesenchymal transition markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Current prospects for RNA interference-based therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Down-regulation of osteopontin attenuates breast tumour progression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Cyclooxygenase-2 inhibitors down-regulate osteopontin and Nr4A2-new therapeutic targets for colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin is a new target molecule for ovarian clear cell carcinoma therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Andrographolide inhibits osteopontin expression and breast tumor growth through down regulation of PI3 kinase/Akt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

CD44, a therapeutic target for metastasising tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin: a potentially important therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Anti-CD44 induces apoptosis in T lymphoma via mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

The role of osteopontin and osteopontin aptamer (OPN-R3) in fibroblast activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Pharmacokinetic characterization of an RNA aptamer against osteopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Plasma osteopontin is a useful diagnostic biomarker for advanced non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Osteopontin is a prognostic biomarker in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

Agelastatin A: a novel inhibitor of osteopontin-mediated adhesion, invasion, and colony formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2014.925447

10.1517/14728222.2014.925447

21 January 2018

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DOI

1 reference

31 August 2017

1 reference