Cell therapy for human ischemic heart diseases: critical review and summary of the clinical experiences. (Q38226693)

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21 March 2020

title

Cell therapy for human ischemic heart diseases: critical review and summary of the clinical experiences (English)

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21 March 2020

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4

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21 March 2020

Zsolt Murlasits

5

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21 March 2020

Gerald Maurer

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Mariann Gyöngyösi

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21 March 2020

author name string

Noemi Pavo

1

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21 March 2020

Silvia Charwat

2

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21 March 2020

Noemi Nyolczas

3

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21 March 2020

Jutta Bergler-Klein

6

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21 March 2020

Mariam Nikfardjam

7

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21 March 2020

Imre Benedek

8

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21 March 2020

Teodora Benedek

9

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21 March 2020

Imre J Pavo

10

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21 March 2020

Bernard J Gersh

11

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21 March 2020

Kurt Huber

12

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21 March 2020

publication date

3 July 2014

1 reference

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Journal of Molecular and Cellular Cardiology

21 March 2020

published in

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21 March 2020

volume

75

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21 March 2020

page(s)

12-24

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Adult cardiac stem cells are multipotent and support myocardial regeneration

21 March 2020

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[Regenerative therapy in patients with a revascularized acute anterior myocardial infarction and depressed ventricular function]

7 January 2021

1 reference

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Intracoronary transplantation of non-expanded peripheral blood-derived mononuclear cells promotes improvement of cardiac function in patients with acute myocardial infarction

7 January 2021

1 reference

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Effect of intracoronary injection of mononuclear bone marrow stem cells on left ventricular function in patients with acute myocardial infarction.

7 January 2021

1 reference

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Influence of intracoronary injections of bone-marrow-derived mononuclear cells on large myocardial infarction outcome: quantum of initial necrosis is the key.

7 January 2021

1 reference

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A pilot trial to assess potential effects of selective intracoronary bone marrow-derived progenitor cell infusion in patients with nonischemic dilated cardiomyopathy: final 1-year results of the transplantation of progenitor cells and functional reg

7 January 2021

1 reference

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Results of intracoronary stem cell therapy after acute myocardial infarction

7 January 2021

1 reference

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Bone marrow cell transplantation improves cardiac, autonomic, and functional indexes in acute anterior myocardial infarction patients (Cardiac Study).

7 January 2021

1 reference

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Influence of bone marrow stem cells on left ventricle perfusion and ejection fraction in patients with acute myocardial infarction of anterior wall: randomized clinical trial: Impact of bone marrow stem cell intracoronary infusion on improvement of

7 January 2021

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[Long-term changes in left ventricular function following intracoronary stem cell transplantation for acute myocardial infarction]

7 January 2021

1 reference

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Improvement of cardiac function by intracoronary freshly isolated bone marrow cells transplantation in patients with acute myocardial infarction

7 January 2021

1 reference

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Is the measurement of left ventricular ejection fraction the proper end point for cell therapy trials? An analysis of the effect of bone marrow mononuclear stem cell administration on left ventricular ejection fraction after ST-segment elevation myo

7 January 2021

1 reference

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Effects of intracoronary stem cell transplantation in patients with dilated cardiomyopathy

7 January 2021

1 reference

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Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure

7 January 2021

1 reference

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Direct intramyocardial percutaneous delivery of autologous bone marrow in patients with refractory myocardial angina.

7 January 2021

1 reference

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Intramyocardial injection of autologous bone marrow mononuclear cells in patients with chronic myocardial infarction and severe left ventricular dysfunction

7 January 2021

1 reference

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Electrophysiological and arrhythmogenic effects of intramyocardial bone marrow cell injection in patients with chronic ischemic heart disease

7 January 2021

1 reference

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Intramyocardial bone marrow cell transplantation and the progression of coronary atherosclerosis in patients with chronic myocardial ischemia.

7 January 2021

1 reference

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Intramyocardial bone marrow cell injection for chronic myocardial ischemia: a randomized controlled trial

7 January 2021

1 reference

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Percutaneous intramyocardial stem cell injection in patients with acute myocardial infarction: first-in-man study

7 January 2021

1 reference

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[Diabetic and nondiabetic patients respond differently to transendocardial injection of bone marrow mononuclear cells: findings from prospective clinical trials in "no-option" patients]

7 January 2021

1 reference

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Efficiency of intramyocardial injections of autologous bone marrow mononuclear cells in patients with ischemic heart failure: a randomized study

7 January 2021

1 reference

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Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial

7 January 2021

1 reference

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Myocardial blood flow and infarct size after CD133+ cell injection in large myocardial infarction with good recanalization and poor reperfusion: results from a randomized controlled trial.

7 January 2021

1 reference

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Combination stem cell therapy for the treatment of medically refractory coronary ischemia: a Phase I study.

7 January 2021

1 reference

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The role of PET with 13N-ammonia and 18F-FDG in the assessment of myocardial perfusion and metabolism in patients with recent AMI and intracoronary stem cell injection

7 January 2021

1 reference

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Safety and efficacy of consecutive cycles of granulocyte-colony stimulating factor, and an intracoronary CD133+ cell infusion in patients with chronic refractory ischemic heart disease: the G-CSF in angina patients with IHD to stimulate neovasculari

7 January 2021

1 reference

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Granulocyte-colony stimulating factor or granulocyte-colony stimulating factor associated to stem cell intracoronary infusion effects in non ischemic refractory heart failure

7 January 2021

1 reference

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Intracoronary stem cell infusion in heart transplant candidates.

7 January 2021

1 reference

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[Effects of autologous bone marrow derived CD34+ stem cells on the left ventricular function following myocardial infarction]

7 January 2021

1 reference

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Effect of intracoronary transplantation of autologous bone marrow-derived mononuclear cells on outcomes of patients with refractory chronic heart failure secondary to ischemic cardiomyopathy

7 January 2021

1 reference

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Intracoronary autologous CD34+ stem cell therapy for intractable angina

7 January 2021

1 reference

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Stem cell mobilization by granulocyte colony-stimulating factor for myocardial recovery after acute myocardial infarction: a meta-analysis

7 January 2021

1 reference

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Stem Cell Mobilization Induced by Subcutaneous Granulocyte-Colony Stimulating Factor to Improve Cardiac Regeneration After Acute ST-Elevation Myocardial Infarction: Result of the Double-Blind, Randomized, Placebo-Controlled Stem Cells in Myocardial I

7 January 2021

1 reference

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Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial

7 January 2021

1 reference

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Autologous bone marrow stem cell mobilization induced by granulocyte colony-stimulating factor after subacute ST-segment elevation myocardial infarction undergoing late revascularization: final results from the G-CSF-STEMI (Granulocyte Colony-Stimul

7 January 2021

1 reference

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Usefulness of Granulocyte Colony-Stimulating Factor in Patients With a Large Anterior Wall Acute Myocardial Infarction to Prevent Left Ventricular Remodeling (The Rigenera Study)

7 January 2021

1 reference

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Autologous bone-marrow stem-cell transplantation for myocardial regeneration

7 January 2021

1 reference

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Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction

7 January 2021

1 reference

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Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: phase I clinical study with 12 months of follow-up.

7 January 2021

1 reference

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Feasibility and safety of autologous myoblast transplantation in patients with ischemic cardiomyopathy.

7 January 2021

1 reference

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Autologous bone marrow-derived stem cell therapy in heart disease: discrepancies and contradictions

7 January 2021

1 reference

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Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis

7 January 2021

1 reference

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Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis

7 January 2021

1 reference

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Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials.

7 January 2021

1 reference

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Autologous transplantation of blood-derived stem/progenitor cells for ischaemic heart disease

7 January 2021

1 reference

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Intracoronary blood- or bone marrow-derived cell transplantation in patients with ischemic heart disease

7 January 2021

1 reference

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Intracoronary autologous bone marrow stem cells transfer for patients with acute myocardial infarction: a meta-analysis of randomised controlled trials

7 January 2021

1 reference

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Impact of timing on efficacy and safetyof intracoronary autologous bone marrow stem cells transplantation in acute myocardial infarction: a pooled subgroup analysis of randomized controlled trials

7 January 2021

1 reference

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Stem cells improve left ventricular function in acute myocardial infarction.

7 January 2021

1 reference

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Effects of intracoronary autologous bone marrow cells on left ventricular function in acute myocardial infarction: a systematic review and meta-analysis for randomized controlled trials

7 January 2021

1 reference

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Short- and long-term outcomes of intracoronary and endogenously mobilized bone marrow stem cells in the treatment of ST-segment elevation myocardial infarction: a meta-analysis of randomized control trials

7 January 2021

1 reference

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Bone Marrow Stem Cell Treatment for Ischemic Heart Disease in Patients with No Option of Revascularization: A Systematic Review and Meta-Analysis

7 January 2021

1 reference

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Stem cell therapy is a promising tool for refractory angina: a meta-analysis of randomized controlled trials

7 January 2021

1 reference

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Multicenter randomized trial of cell therapy in cardiopathies - MiHeart Study.

7 January 2021

1 reference

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Serial noninvasive in vivo positron emission tomographic tracking of percutaneously intramyocardially injected autologous porcine mesenchymal stem cells modified for transgene reporter gene expression.

7 January 2021

1 reference

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Development of a network to test strategies in cardiovascular cell delivery: the NHLBI-sponsored Cardiovascular Cell Therapy Research Network (CCTRN).

7 January 2021

1 reference

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Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial

7 January 2021

1 reference

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Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study.

7 January 2021

1 reference

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The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction

7 January 2021

1 reference

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Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up

7 January 2021

1 reference

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Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5-year results suggest long-term safety and efficacy

7 January 2021

1 reference

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Differentiation of pluripotent embryonic stem cells into cardiomyocytes.

7 January 2021

1 reference

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Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization

7 January 2021

1 reference

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Stable benefit of embryonic stem cell therapy in myocardial infarction.

7 January 2021

1 reference

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Nuclear reprogramming to a pluripotent state by three approaches

7 January 2021

1 reference

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

7 January 2021

1 reference

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Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

A functionally characterized test set of human induced pluripotent stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Variation in the safety of induced pluripotent stem cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Molecular imaging of induced pluripotent stem cell immunogenicity with in vivo development in ischemic myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Reprogramming of human fibroblasts toward a cardiac fate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Making steady progress on direct cardiac reprogramming toward clinical application

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Nuclear reprogramming strategy modulates differentiation potential of induced pluripotent stem cells

7 January 2021

1 reference

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Cell therapy for the treatment of coronary heart disease: a critical appraisal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Human mesenchymal stem cells modulate allogeneic immune cell responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Key developments in stem cell therapy in cardiology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction

7 January 2021

1 reference

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Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Derivation of a cardiopoietic population from human mesenchymal stem cells yields cardiac progeny

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Combinatorial polymer electrospun matrices promote physiologically-relevant cardiomyogenic stem cell differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Biomaterial strategies for alleviation of myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Design and characterization of an injectable pericardial matrix gel: a potentially autologous scaffold for cardiac tissue engineering

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Bioengineering heart muscle: a paradigm for regenerative medicine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Cardiac regenerative medicine: cellular therapy and tissue engineering.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Myocardial tissue engineering

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Mesenchymal stem cell adhesion to cardiac microvascular endothelium: activators and mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

The dying stem cell hypothesis: immune modulation as a novel mechanism for progenitor cell therapy in cardiac muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Irradiated cultured apoptotic peripheral blood mononuclear cells regenerate infarcted myocardium.

7 January 2021

1 reference

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Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Circulating microRNAs as biomarkers and potential paracrine mediators of cardiovascular disease

7 January 2021

1 reference

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Long-acting beneficial effect of percutaneously intramyocardially delivered secretome of apoptotic peripheral blood cells on porcine chronic ischemic left ventricular dysfunction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016

Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.06.016