Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease (Q38227267)

31 August 2017

Pathogenesis of antineutrophil cytoplasmic autoantibody-mediated disease (English)

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31 August 2017

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J Charles Jennette

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31 August 2017

Ronald J Falk

series ordinal

2

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31 August 2017

language of work or name

English

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publication date

8 July 2014

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Nature Reviews Rheumatology

31 August 2017

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31 August 2017

10

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31 August 2017

463-473

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31 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2014.103

31 August 2017

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cites work

2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Classification of antineutrophil cytoplasmic autoantibody vasculitides: the role of antineutrophil cytoplasmic autoantibody specificity for myeloperoxidase or proteinase 3 in disease recognition and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Genetically distinct subsets within ANCA-associated vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Trojan horses: drug culprits associated with antineutrophil cytoplasmic autoantibody (ANCA) vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Rheumatic manifestations of cocaine use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Elevated antilysosomal-associated membrane protein-2 antibody levels in patients with adult Henoch-Schönlein purpura.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Does analysis of the antigenic specificities of anti-neutrophil cytoplasmic antibodies contribute to their clinical significance in the inflammatory bowel diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

PR3-ANCA: a promising biomarker for ulcerative colitis with extensive disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Systemic lupus erythematosus associated with ANCA-associated vasculitis: an overlapping syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Clinical features and outcome of patients with both ANCA and anti-GBM antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Nomenclature and classification of vasculitis: lessons learned from granulomatosis with polyangiitis (Wegener's granulomatosis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

The pulmonary biopsy in the early diagnosis of Wegener's (pathergic) granulomatosis: A study based on 35 open lung biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Histologic analysis of renal leukocyte infiltration in antineutrophil cytoplasmic antibody-associated vasculitis: importance of monocyte and neutrophil infiltration in tissue damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Netting neutrophils in autoimmune small-vessel vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

The rise and fall of horror autotoxicus and forbidden clones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Asymptomatic autoantibodies associate with future anti-glomerular basement membrane disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Comparison of characteristics of natural autoantibodies against myeloperoxidase and anti-myeloperoxidase autoantibodies from patients with microscopic polyangiitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Relation between asymptomatic proteinase 3 antibodies and future granulomatosis with polyangiitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Staphylococcus aureus and Wegener's granulomatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Segmental necrotising glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Autoimmunity is triggered by cPR-3(105-201), a protein complementary to human autoantigen proteinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

New insights that link microbes with the generation of antineutrophil cytoplasmic autoantibodies: the theory of autoantigen complementarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Specific interactions between sense and complementary peptides: the basis for the proteomic code

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

ANCA patients have T cells responsive to complementary PR-3 antigen

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Apoptosis-induced proteinase 3 membrane expression is independent from degranulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Decreased numbers of blood dendritic cells and defective function of regulatory T cells in antineutrophil cytoplasmic antibody-associated vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Patients with antineutrophil cytoplasmic antibody-associated vasculitis have defective Treg cell function exacerbated by the presence of a suppression-resistant effector cell population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Aberrant expression of the negative costimulator PD-1 on T cells in granulomatosis with polyangiitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Decreased CD5⁺ B cells in active ANCA vasculitis and relapse after rituximab.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Regulatory B cells in ANCA-associated vasculitis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Regulation of B-cell-activating factor (BAFF)/B lymphocyte stimulator (BLyS) expression in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Plasma levels of soluble interleukin 2 receptor, soluble CD30, interleukin 10 and B cell activator of the tumour necrosis factor family during follow-up in vasculitis associated with proteinase 3-antineutrophil cytoplasmic antibodies: associations w

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

B-lymphocyte activating factor levels are increased in patients with Wegener's granulomatosis and inversely correlated with ANCA titer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Activation of the G(i) heterotrimeric G protein by ANCA IgG F(ab')2 fragments is necessary but not sufficient to stimulate the recruitment of those downstream mediators used by intact ANCA IgG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

p38MAPK, ERK and PI3K signaling pathways are involved in C5a-primed neutrophils for ANCA-mediated activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Antimyeloperoxidase antibodies induce neutrophil adherence to cultured human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Monocyte activation in patients with Wegener's granulomatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

The role of myeloperoxidase and myeloperoxidase-antineutrophil cytoplasmic antibodies (MPO-ANCAs) in the pathogenesis of human MPO-ANCA-associated glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Experimental models of vasculitis and glomerulonephritis induced by antineutrophil cytoplasmic autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Pathogenesis of ANCA-associated vasculitis: recent insights from animal models

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Animal models of antineutrophil cytoplasm antibody-associated vasculitis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-proteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

C5a receptor (CD88) blockade protects against MPO-ANCA GN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

The role of the innate immune system in granulomatous disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Is PR3-ANCA formation initiated in Wegener's granulomatosis lesions? Granulomas as potential lymphoid tissue maintaining autoantibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Serum anti-lysosomal-associated membrane protein-2 antibody levels in cutaneous polyarteritis nodosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Colocalization of ANCA-antigens and fibrinoid necrosis in ANCA-associated vasculitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

On the specific mutual interaction of amino acid residues of polypeptide chains and amino acid residues with codons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Idiotypic induction of autoimmunity: a new aspect of the idiotypic network.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Patients with Wegener's granulomatosis demonstrate a relative deficiency and functional impairment of T-regulatory cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

BAFF is elevated in serum of patients with Wegener's granulomatosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Serum levels of BAFF and APRIL in myeloperoxidase anti-neutrophil cytoplasmic autoantibody-associated renal vasculitis: association with disease activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Myeloperoxidase binds to vascular endothelial cells, is recognized by ANCA and can enhance complement dependent cytotoxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Mediation of endothelial cell damage by serine proteases, but not superoxide, released from antineutrophil cytoplasmic antibody-stimulated neutrophils

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Bone marrow-derived cells are sufficient and necessary targets to mediate glomerulonephritis and vasculitis induced by anti-myeloperoxidase antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.103

Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils

31 March 2020

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12 December 2020

Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3.

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12 December 2020

Crosslinking of ANCA-antigens stimulates superoxide release by human neutrophils

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12 December 2020

Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic Rhinosinusitis with nasal polyps.

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12 December 2020

Antibodies to neutrophil cytoplasmic antigens induce monocyte chemoattractant protein-1 secretion from human monocytes

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12 December 2020

Cross-linking of Fc gamma receptor IIa and Fc gamma receptor IIIb induces different proadhesive phenotypes on human neutrophils

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12 December 2020

Allergic granulomatosis, allergic angiitis, and periarteritis nodosa

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12 December 2020

Prominence of cell-mediated immunity effectors in "pauci-immune" glomerulonephritis

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12 December 2020

Glomerular monocyte-macrophage features in ANCA-positive renal vasculitis and cryoglobulinemic nephritis

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12 December 2020

Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase

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12 December 2020

Antibodies against granule proteins activate neutrophils in vitro

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12 December 2020

Presence of neutrophil extracellular traps and antineutrophil cytoplasmic antibodies associated with vasculitides

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12 December 2020

Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies.

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12 December 2020

Antineutrophil cytoplasmic antibodies (ANCAs) in patients with inflammatory bowel disease show no correlation with proteinase 3, lactoferrin, myeloperoxidase, elastase, cathepsin G and lysozyme: a Singapore study

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12 December 2020

Current knowledge on cellular interactions in the WG-granuloma.

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12 December 2020

Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils via Fc gamma RIIa

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12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2014.103

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Dimensions Publication ID

31 August 2017

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