1,4-naphthoquinones: from oxidative damage to cellular and inter-cellular signaling (Q38251996)

30 June 2019

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2 October 2019

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13 November 2019

1,4-naphthoquinones: from oxidative damage to cellular and inter-cellular signaling (English)

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30 June 2019

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2 October 2019

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7 November 2019

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12 November 2019

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13 November 2019

1

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author name string

Xiaoqing Hou

series ordinal

2

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30 June 2019

Claus Jacob

series ordinal

3

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30 June 2019

language of work or name

English

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publication date

17 September 2014

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2 October 2019

7 November 2019

12 November 2019

13 November 2019

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2 October 2019

7 November 2019

12 November 2019

13 November 2019

19

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issue

9

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page(s)

14902-14918

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Creative Commons Attribution

copyright license

4 references

2 October 2019

7 November 2019

12 November 2019

13 November 2019

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The discovery of vitamin K and its clinical applications

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https://api.crossref.org/works/10.3390%2FMOLECULES190914902

1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Cytotoxic action of juglone and plumbagin: a mechanistic study using HaCaT keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Toxic drug effects associated with oxygen metabolism: redox cycling and lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Enzyme-catalyzed activation of anticancer prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Cooperation of NAD(P)H:quinone oxidoreductase 1 and UDP-glucuronosyltransferases reduces menadione cytotoxicity in HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Mechanisms of toxicity of 2- and 5-hydroxy-1,4-naphthoquinone; absence of a role for redox cycling in the toxicity of 2-hydroxy-1,4-naphthoquinone to isolated hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

DT-diaphorase-catalysed reduction of 1,4-naphthoquinone derivatives and glutathionyl-quinone conjugates. Effect of substituents on autoxidation rates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

The chemical biology of naphthoquinones and its environmental implications

21 January 2018

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https://api.crossref.org/works/10.3390%2FMOLECULES190914902

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Chemical structures of inducers of nicotinamide quinone oxidoreductase 1 (NQO1).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Glucose availability is a decisive factor for Nrf2-mediated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Naphthazarin protects against glutamate-induced neuronal death via activation of the Nrf2/ARE pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Extension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Molecular mechanisms of quinone cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

5,8-Dimethoxy-2-Nonylamino-Naphthalene-1,4-Dione Inhibits Vascular Smooth Muscle Cell Proliferation by Blocking Autophosphorylation of PDGF-Receptor β.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Anti-proliferative actions of 2-decylamino-5,8-dimethoxy-1,4-naphthoquinone in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Epidermal growth factor- and stress-induced loss of gap junctional communication is mediated by ERK-1/ERK-2 but not ERK-5 in rat liver epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Quinone-induced Cdc25A inhibition causes ERK-dependent connexin phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Life cycle of connexins in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

The effects of connexin phosphorylation on gap junctional communication

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Regulation of gap junctions by tyrosine protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Role of oxidant stress in lawsone-induced hemolytic anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to quartz particles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to carbon or silica-based nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Posttranscriptional regulation of connexin-43 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Regulation of protein tyrosine phosphatases by reversible oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Chemical knockdown of protein-tyrosine phosphatase 1B by 1,2-naphthoquinone through covalent modification causes persistent transactivation of epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Perspectives on medicinal properties of plumbagin and its analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Enhancing the antitumor activity of adriamycin and ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Superoxide Enhances the Antitumor Combination of AdMnSOD Plus BCNU in Breast Cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Multifunctional redox catalysts as selective enhancers of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Regulating mammalian checkpoints through Cdc25 inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

ERBB receptors and cancer: the complexity of targeted inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

The ERBB network: at last, cancer therapy meets systems biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Targeting the ERBB family in cancer: couples therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Therapy with epidermal growth factor receptor inhibitors. Clinical spectrum of cutaneous adverse effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Interdisciplinary management of EGFR-inhibitor-induced skin reactions: a German expert opinion.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES190914902

2-Methyl-1,4-naphthoquinone, vitamin K(3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade.

21 January 2018

1 reference

12 December 2020

Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element

1 reference

12 December 2020

Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants

1 reference

12 December 2020

Effect of hydroxy substituent position on 1,4-naphthoquinone toxicity to rat hepatocytes

1 reference

12 December 2020

Inhibitory effect of a novel naphthoquinone derivative on proliferation of vascular smooth muscle cells through suppression of platelet-derived growth factor receptor β tyrosine kinase

1 reference

12 December 2020

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells

1 reference

12 December 2020

Menadione cytotoxicity to Hep G2 cells and protection by activation of nuclear factor-kappaB.

1 reference

12 December 2020

10.3390/MOLECULES190914902

Identifiers

DOI

1 reference

30 June 2019

release_l4cygucylnh37krk3arcfmfhyq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/l4cygucylnh37krk3arcfmfhyq

24 November 2022

mapped directly with Wikidata item

PMCID

6270801

1 reference

30 June 2019

PubMed ID

25232709

1 reference

30 June 2019