Role of Nrf2 in chronic liver disease. (Q38256342)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278702%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

review article

1 reference

title

Role of Nrf2 in chronic liver disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278702%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

main subject

chronic liver disease

0 references

author

Murugavel Ponnusamy

3

1 reference

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20 February 2020

author name string

Wei Tang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278702%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Yong-Fang Jiang

2

1 reference

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20 February 2020

Mamadou Diallo

4

1 reference

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20 February 2020

language of work or name

English

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publication date

1 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278702%20AND%20SRC:MED&resulttype=core&format=json

World Journal of Gastroenterology

20 February 2020

published in

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20 February 2020

volume

20

1 reference

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20 February 2020

issue

36

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20 February 2020

page(s)

13079-13087

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Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration

20 February 2020

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Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model

6 September 2017

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Nuclear factor (erythroid-derived 2)-like-2 factor (Nrf2), a key regulator of the antioxidant response to protect against atherosclerosis and nonalcoholic steatohepatitis

6 September 2017

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New player on an old field; the keap1/Nrf2 pathway as a target for treatment of type 2 diabetes and metabolic syndrome

6 September 2017

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The protective effect of glycyrrhetinic acid on carbon tetrachloride-induced chronic liver fibrosis in mice via upregulation of Nrf2.

6 September 2017

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Lucidone suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction

6 September 2017

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Glutathione synthesis

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Differential hepatoprotective mechanisms of rutin and quercetin in CCl(4)-intoxicated BALB/cN mice

6 September 2017

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Nrf2: a potential target for new therapeutics in liver disease

6 September 2017

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Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway

6 September 2017

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Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity

6 September 2017

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The effect of alcohol on postprandial and fasting triglycerides

6 September 2017

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Hepatitis C virus proteins activate NRF2/ARE pathway by distinct ROS-dependent and independent mechanisms in HUH7 cells.

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Nrf2:INrf2 (Keap1) signaling in oxidative stress

6 September 2017

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Histological patterns in drug-induced liver disease

6 September 2017

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6 September 2017

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Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

6 September 2017

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Molecular mechanisms of Nrf2-mediated antioxidant response

6 September 2017

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Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

6 September 2017

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Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

6 September 2017

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

6 September 2017

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

6 September 2017

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Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.

6 September 2017

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Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

6 September 2017

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

6 September 2017

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Functional antioxidant responsive elements.

6 September 2017

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Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

6 September 2017

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Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma

6 September 2017

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Sulforaphane attenuates hepatic fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling

6 September 2017

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Hypoxia-inducible factor-1 (HIF-1) promotes LDL and VLDL uptake through inducing VLDLR under hypoxia

6 September 2017

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Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress

6 September 2017

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Hepatitis C virus impairs the induction of cytoprotective Nrf2 target genes by delocalization of small Maf proteins

6 September 2017

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Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway

14 September 2017

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HBx or HCV core gene expression in HepG2 human liver cells results in a survival benefit against oxidative stress with possible implications for HCC development

14 September 2017

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Hepatitis B virus replication causes oxidative stress in HepAD38 liver cells

14 September 2017

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Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells

14 September 2017

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Hepatitis B virus induces expression of antioxidant response element-regulated genes by activation of Nrf2.

14 September 2017

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Effects of tocotrienol on tumor necrosis factor-α/d-galactosamine-induced steatohepatitis in rats

28 September 2017

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Anti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitis

28 September 2017

1 reference

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Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice.

28 September 2017

1 reference

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Administration of a murine diet supplemented with conjugated linoleic acid increases the expression and activity of hepatic uncoupling proteins.

23 June 2018

1 reference

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Carthamus red from Carthamus tinctorius L. exerts antioxidant and hepatoprotective effect against CCl(4)-induced liver damage in rats via the Nrf2 pathway

23 June 2018

1 reference

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Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor

31 August 2018

1 reference

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Nrf2 inhibits LXRα-dependent hepatic lipogenesis by competing with FXR for acetylase binding.

31 August 2018

1 reference

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Nimesulide-induced electrophile stress activates Nrf2 in human hepatocytes and mice but is not sufficient to induce hepatotoxicity in Nrf2-deficient mice

31 August 2018

1 reference

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Hepatitis C virus core protein compromises iron-induced activation of antioxidants in mice and HepG2 cells

31 August 2018

1 reference

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Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

31 August 2018

1 reference

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CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappaB pathway: role of a novel plant protein

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Acetaminophen toxicity: changing perceptions on a social/medical issue

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Glutathione metabolism and antioxidant enzymes in patients affected by nonalcoholic steatohepatitis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Low dose of oleanolic acid protects against lithocholic acid-induced cholestasis in mice: potential involvement of nuclear factor-E2-related factor 2-mediated upregulation of multidrug resistance-associated proteins

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177487

Chronic ethanol and triglyceride turnover in white adipose tissue in rats: inhibition of the anti-lipolytic action of insulin after chronic ethanol contributes to increased triglyceride degradation

1 October 2018

1 reference

12 December 2020

Dysregulated expression of fatty acid oxidation enzymes and iron-regulatory genes in livers of Nrf2-null mice

1 reference

12 December 2020

Nonalcoholic fatty liver disease

1 reference

12 December 2020

Aqueous extract of Artemisia capillaris exerts hepatoprotective action in alcohol-pyrazole-fed rat model

1 reference

12 December 2020

Oxidative stress and alcoholic liver disease

1 reference

12 December 2020

Nonalcoholic fatty liver disease

1 reference

12 December 2020

Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver

1 reference

12 December 2020

Induction of Nrf2 and metallothionein as a common mechanism of hepatoprotective medicinal herbs

1 reference

12 December 2020

Severe hypertriglyceridemia influenced by alcohol (SHIBA)

1 reference

12 December 2020

Non-alcoholic fatty liver disease

1 reference

12 December 2020

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

1 reference

12 December 2020

Repeated oral administration of oleanolic acid produces cholestatic liver injury in mice

1 reference

12 December 2020

The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant

1 reference

12 December 2020

10.3748/WJG.V20.I36.13079

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278702%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278702%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

25278702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25278702%20AND%20SRC:MED&resulttype=core&format=json