Insulin receptor kinase defects in insulin-resistant tissues and their role in the pathogenesis of NIDDM. (Q38283205)

1 September 2017

1 reference

title

Insulin receptor kinase defects in insulin-resistant tissues and their role in the pathogenesis of NIDDM. (English)

1 reference

1 September 2017

0 references

1 reference

1

Häring H

1 reference

1 September 2017

Obermaier-Kusser B

2

1 reference

1 September 2017

1 August 1989

1 reference

Diabetes/metabolism reviews

1 September 2017

1 reference

1 September 2017

5

1 reference

1 September 2017

5

1 reference

1 September 2017

431-441

1 reference

Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus.

1 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Impact of glucose ingestion on hepatic and peripheral glucose metabolism in man: an analysis based on simultaneous use of the forearm and double isotope techniques

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Cellular alterations responsible for insulin resistance in obesity and type II diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin secretion and action in noninsulin-dependent diabetes mellitus. Is insulin resistance secondary to hypoinsulinemia?

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin secretion in diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin receptor: structure and function

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin receptor phosphorylation in intact adipocytes and in a cell-free system

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phosphorylation of the hepatic insulin receptor: stimulating effect of insulin on intact cells and in a cell-free system

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phosphorylation and dephosphorylation of the insulin receptor: evidence against an intrinsic phosphatase activity

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Tyrosine-specific protein kinase activity is associated with the purified insulin receptor

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the M r 95,000 receptor subunit is its own kinase

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Two different protein kinase activities are associated with the insulin receptor

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phosphorylation of purified insulin receptor by cAMP kinase.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Two systems in vitro that show insulin-stimulated serine kinase activity towards the insulin receptor

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

An Mr 180,000 protein is an endogenous substrate for the insulin-receptor-associated tyrosine kinase in human placenta

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Identification of a cellular 110 000-Da protein substrate for the insulin-receptor kinase

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin and insulin-like growth factor 1 stimulate the phosphorylation on tyrosine of a 160 kDa cytosolic protein in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin activates phospholipase C in fat cells: similarity with the activation of pyruvate dehydrogenase

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Purification of a phosphatidylinositol-glycan-specific phospholipase C from liver plasma membranes: a possible target of insulin action

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Evidence that the insulin receptor-associated protein kinase acts as a phosphatidylinositol kinase

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Characterization of phosphatidylinositol kinase activity associated with the insulin receptor

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin stimulates the generation from hepatic plasma membranes of modulators derived from an inositol glycolipid

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Studies and perspectives of protein kinase C.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Further evidence implicating diacylglycerol generation and protein kinase C activation in agonist-induced increases in glucose uptake. Insulin-like effects of phenylephrine in BC3H-1 myocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phorbolesters enhance basal D-glucose transport but inhibit insulin stimulation of D-glucose transport and insulin binding in isolated rat adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phorbol esters imitate in rat fat-cells the full effect of insulin on glucose-carrier translocation, but not on 3-O-methylglucose-transport activity

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Structural and functional roles of glycosyl-phosphatidylinositol in membranes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin stimulates the phosphorylation level of v-Ha-ras protein in membrane fraction.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Multisite phosphorylation of the alpha subunit of transducin by the insulin receptor kinase and protein kinase C.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and Go.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Interaction of the insulin receptor kinase with serine/threonine kinases in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Inhibition of proliferation of cloudman S91 melanoma cells by insulin and characterization of some insulin-resistant variants

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Abnormality of insulin binding and receptor phosphorylation in an insulin-resistant melanoma cell line

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Protein kinase activity of the insulin receptor from muscle

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Alteration of insulin receptor kinase in obese, insulin-resistant mice.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Diabetes-induced functional and structural changes in insulin receptors from rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Defect in Phosphorylation of Insulin Receptors in Cells from an Insulin-Resistant Patient with Normal Insulin Binding

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Characterization of binding and phosphorylation defects of erythrocyte insulin receptors in the type A syndrome of insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Effect of cyclic AMP-dependent protein kinase on insulin receptor tyrosine kinase activity.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Phospholipid environment alters hormone-sensitivity of the purified insulin receptor kinase

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Autophosphorylation of the insulin receptor in rat adipocytes is modulated by thyroid hormone status

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Studies on the mechanism of insulin resistance in the liver from humans with noninsulin-dependent diabetes. Insulin action and binding in isolated hepatocytes, insulin receptor structure, and kinase activity

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Insulin receptor kinase in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Catecholamine-induced insulin resistance of glucose transport in isolated rat adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610050502

7 January 2021

Identifiers

DOI

10.1002/DMR.5610050502

0 references

PubMed ID

2547553

1 reference

PubMed ID

2547553