Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy (Q38287263)

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Language	Label	Description	Also known as
English	Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

1 September 2017

Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy (English)

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Europe PubMed Central

1 September 2017

phase II clinical trial

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inferred from title

Eleonora Aronica

4

object named as

Eleonora Aronica

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Europe PubMed Central

1 September 2017

author name string

Valerie Ferreira

1

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Europe PubMed Central

1 September 2017

Jaap Twisk

2

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Europe PubMed Central

1 September 2017

Karin Kwikkers

3

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Europe PubMed Central

1 September 2017

Diane Brisson

5

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Europe PubMed Central

1 September 2017

Julie Methot

6

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Europe PubMed Central

1 September 2017

Harald Petry

7

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Europe PubMed Central

1 September 2017

Daniel Gaudet

8

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Europe PubMed Central

1 September 2017

publication date

28 February 2014

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Europe PubMed Central

1 September 2017

Human Gene Therapy

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Europe PubMed Central

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25

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Europe PubMed Central

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3

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Europe PubMed Central

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180-188

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Europe PubMed Central

1 September 2017

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression

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Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial

1 reference

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The complex and evolving story of T cell activation to AAV vector-encoded transgene products

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1 reference

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AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

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Skeletal muscle fibers express major histocompatibility complex class II antigens independently of inflammatory infiltrates in inflammatory myopathies

1 reference

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Human lipoprotein lipase: relationship of activity, heparin affinity, and conformation as studied with monoclonal antibodies

1 reference

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Increased intracellular triglyceride in C(2)C(12) muscle cells transfected with human lipoprotein lipase

1 reference

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Preexisting immunity and low expression in primates highlight translational challenges for liver-directed AAV8-mediated gene therapy

1 reference

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Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults

1 reference

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1 reference

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Effect of alipogene tiparvovec (AAV1-LPL(S447X)) on postprandial chylomicron metabolism in lipoprotein lipase-deficient patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24299335

12 December 2020

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1 reference

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12 December 2020

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1 reference

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12 December 2020

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Identifiers

10.1089/HUM.2013.169

1 reference

Europe PubMed Central

1 September 2017

1 reference

Europe PubMed Central

1 September 2017

1 reference

Europe PubMed Central

1 September 2017

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