Immortal activated human hepatic stellate cells generated by ectopic telomerase expression (Q38291132)

1 September 2017

Immortal activated human hepatic stellate cells generated by ectopic telomerase expression (English)

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1 September 2017

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1

Bernd Schnabl

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1 September 2017

Youkyung Hwang Choi

2

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1 September 2017

John C Olsen

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3

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1 September 2017

Curt H Hagedorn

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4

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1 September 2017

David A Brenner

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5

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1 September 2017

1 March 2002

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1 September 2017

Laboratory Investigation

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1 September 2017

82

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3

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323-333

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describes a project that uses

1 September 2017

hTERT-HSC

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exact match

https://scigraph.springernature.com/pub.10.1038/labinvest.3780426

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cites work

Telomere length predicts replicative capacity of human fibroblasts

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Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis

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Extension of life-span by introduction of telomerase into normal human cells

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Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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Biological assays for cellular transformation

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Purified Rat Liver Fat-Storing Cells in Culture Divide and Contain Collagen

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Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

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Isolated hepatic lipocytes and kupffer cells from normal human liver: Morphological and functional characteristics in primary culture

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Telomerase expression restores dermal integrity to in vitro-aged fibroblasts in a reconstituted skin model.

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A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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Creation of human tumour cells with defined genetic elements

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Telomeres shorten during ageing of human fibroblasts

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Effect of host modification and age on airway epithelial gene transfer mediated by a murine leukemia virus-derived vector

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

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Specific association of human telomerase activity with immortal cells and cancer

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential

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7 January 2021

Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease

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7 January 2021

Nuclear factor kappaB in proliferation, activation, and apoptosis in rat hepatic stellate cells

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes

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7 January 2021

Collagen measured in primary cultures of normal rat hepatocytes derives from lipocytes within the monolayer

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7 January 2021

Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

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7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

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7 January 2021

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780426

7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780426

7 January 2021

Glial fibrillary acidic protein--a cell type specific marker for Ito cells in vivo and in vitro

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780426

7 January 2021

Severe growth defect in mouse cells lacking the telomerase RNA component.

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780426

7 January 2021

Appearance of alpha-smooth-muscle-actin-positive cells in hepatic fibrosis

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780426

7 January 2021

Expression of the gene of the alpha-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells

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7 January 2021

Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

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7 January 2021

The role of Smad3 in mediating mouse hepatic stellate cell activation

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7 January 2021

The 5' stem-loop regulates expression of collagen alpha1(I) mRNA in mouse fibroblasts cultured in a three-dimensional matrix

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780426

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780426

7 January 2021

Human endothelial cell life extension by telomerase expression

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7 January 2021

10.1038/LABINVEST.3780426

Identifiers

DOI

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Dimensions Publication ID

1 September 2017

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