Onecut transcription factor OC2 is a direct target of T-bet in type-1 T-helper cells (Q38291705)

1 September 2017

Onecut transcription factor OC2 is a direct target of T-bet in type-1 T-helper cells (English)

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1 September 2017

K Furuno

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K Ikeda

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S Hamano

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K Fukuyama

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M Sonoda

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T Hara

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T Sasazuki

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K Yamamoto

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17 April 2008

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4

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302-308

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https://scigraph.springernature.com/pub.10.1038/gene.2008.18

1 September 2017

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The lineage decisions of helper T cells

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A novel transcription factor, T-bet, directs Th1 lineage commitment

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Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

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T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

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Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

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Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction

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Assessment of clusters of transcription factor binding sites in relationship to human promoter, CpG islands and gene expression

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Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

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Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression

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Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase

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OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6

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Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain

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Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteins

21 January 2018

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OC-3, a novel mammalian member of the ONECUT class of transcription factors

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DNA-binding specificity of the cut repeats from the human cut-like protein

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Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

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Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors

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Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation

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The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration

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The bromodomain mediates transcriptional intermediary factor 1alpha -nucleosome interactions.

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Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 2.

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Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

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7 January 2021

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

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https://api.crossref.org/works/10.1038%2FGENE.2008.18

7 January 2021

Identification of cooperative monomeric Brachyury sites conferring T-bet responsiveness to the proximal IFN-gamma promoter

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7 January 2021

A Distal Enhancer in the Interferon-γ (IFN-γ) Locus Revealed by Genome Sequence Comparison

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https://api.crossref.org/works/10.1038%2FGENE.2008.18

7 January 2021

The T protein encoded by Brachyury is a tissue-specific transcription factor

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https://api.crossref.org/works/10.1038%2FGENE.2008.18

7 January 2021

STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis

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https://api.crossref.org/works/10.1038%2FGENE.2008.18

7 January 2021

Methylation profiling of CpG islands in human breast cancer cells

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https://api.crossref.org/works/10.1038%2FGENE.2008.18

7 January 2021

Identifiers

DOI

10.1038/GENE.2008.18

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Dimensions Publication ID

1 September 2017

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