Identification of amino acid residues critical for biological activity in human interleukin-18. (Q38292971)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11790772%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

Identification of amino acid residues critical for biological activity in human interleukin-18 (English)

1 reference

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6 December 2019

6

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6 December 2019

Menachem Rubinstein

7

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6 December 2019

8

Charles A Dinarello

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6 December 2019

3

Daniela Novick

1 reference

6 December 2019

Soo-Hyun Kim

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11790772%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Tania Azam

2

1 reference

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6 December 2019

Do-Young Yoon

4

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6 December 2019

Leonid L Reznikov

5

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6 December 2019

language of work or name

English

0 references

publication date

14 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11790772%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 December 2019

number of pages

6

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based on heuristic

inferred from page(s)

published in

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6 December 2019

volume

277

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6 December 2019

issue

13

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6 December 2019

page(s)

10998-11003

1 reference

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Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells

6 December 2019

cites work

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Cloning of a new cytokine that induces IFN-gamma production by T cells

21 January 2018

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Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain

21 January 2018

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Purification and characterization of the human interleukin-18 receptor

21 January 2018

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Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling

21 January 2018

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A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

21 January 2018

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Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta

21 January 2018

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IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP

21 January 2018

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Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex

21 January 2018

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IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

21 January 2018

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Identification and initial characterization of four novel members of the interleukin-1 family

21 January 2018

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Four new members expand the interleukin-1 superfamily

21 January 2018

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IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp

21 January 2018

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Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response

21 January 2018

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Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18

21 January 2018

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A novel IL-18BP ELISA shows elevated serum IL-18BP in sepsis and extensive decrease of free IL-18.

21 January 2018

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Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells

21 January 2018

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Identification of human and mouse homologs of the MC51L-53L-54L family of secreted glycoproteins encoded by the Molluscum contagiosum poxvirus

21 January 2018

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Production of a biologically active human interleukin 18 requires its prior synthesis as PRO-IL-18.

21 January 2018

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Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells

21 January 2018

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Interleukin-18 regulates both Th1 and Th2 responses

21 January 2018

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Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta

21 January 2018

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Combining two mutations of human interleukin-6 that affect gp130 activation results in a potent interleukin-6 receptor antagonist on human myeloma cells

21 January 2018

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Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist

21 January 2018

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Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein

21 January 2018

1 reference

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Mapping receptor binding sites in interleukin (IL)-1 receptor antagonist and IL-1 beta by site-directed mutagenesis. Identification of a single site in IL-1ra and two sites in IL-1 beta.

21 January 2018

1 reference

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IL-18 activates STAT3 in the natural killer cell line 92, augments cytotoxic activity, and mediates IFN-gamma production by the stress kinase p38 and by the extracellular regulated kinases p44erk-1 and p42erk-21

21 January 2018

1 reference

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A newly defined interleukin-1?

21 January 2018

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Interleukin‐18 Enhances Lipopolysaccharide‐Induced Interferon‐γ Production in Human Whole Blood Cultures

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M108311200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11790772%20AND%20SRC:MED&resulttype=core&format=json

release_k56anskbaff7remhpibofuy7sa

6 December 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/k56anskbaff7remhpibofuy7sa

mapped directly with Wikidata item

24 November 2022

based on heuristic

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